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CNRS

French National Centre for Scientific Research
Country: France
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3,723 Projects, page 1 of 745
  • Funder: EC Project Code: 307149
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  • Funder: EC Project Code: 630210
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  • Funder: EC Project Code: 702084
    Overall Budget: 173,076 EURFunder Contribution: 173,076 EUR

    The development of quantum networks relies on true single-photon sources and deterministic quantum logic gates. Photons are the most promising flying qubits, capable to propagate long distances without decoherence. However, until now, quantum communications protocols and optical quantum computation have been implemented using defective single-photon sources and probabilistic quantum gates. For a long time, the best single-photon sources have been heralded non-linear crystals where photon-pairs are generated. Such sources can present high coherence properties although they are intrinsically limited to a very low photon flux. This project builds up on major steps obtained in the host team, Laboratoire de Photonique et de Nanostructures, in terms of true single-photon generation and control. By deterministically inserting a quantum dot (QD) in a semiconductor microcavity pillar, the host team fabricated photon sources with quantum properties as good as the currently used sources, but with an unprecedented brightness of 2 orders of magnitude larger. The cavity not only enhances the interaction of the incident photons with the QD state but also the subsequent photon extraction of the device. The Purcell effect diminishes the decoherence processes, constituting an ultrabright source of highly indistinguishable, single-photons. Based on the unique technological, experimental and conceptual knowledge developed by the host team, and on the background of the applicant, our successive objectives is to realize scalable quantum entanglement: to entangle two-photon states with our ultrabright QD-cavity systems at high rates, to use them to perform high fidelity teleportation with long coherence times between 2 different sources, and finally to controllably swap the entanglement between 2 entangled photon-pairs.

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  • Funder: EC Project Code: 751236
    Overall Budget: 185,076 EURFunder Contribution: 141,203 EUR

    During ageing muscle fibers are constantly subjected to high forces resulting in mechanical stress on cells and proteins. As a consequence they can degenerate, leading to suboptimal force generation, lack of coordinated movements and ultimately to muscle failure in the elderly population. This ageing process that leads to a progressive loss of muscle function has a major health impact on the ageing Western society. Physical activity is known to delay this decline. The REBUILD project aims to determine the temporal dynamics of protein replacement during life of a muscle fiber by SILAC-based mass spectrometry and genetics. It will integrate biomechanics with muscle homeostasis and accurately quantify the impact of physical activity on protein turnover and investigate the physiological consequences for the ageing animal. By combining the power of genetics and SILAC-based proteomics with behaviour of free flight under defined exercise conditions, we create a unique position for a discovery orientated large-scale in vivo genetic screen. The interdisciplinary nature of the project will allow establishing novel hypothesis, combining muscle biomechanics as a driving force behind dynamic maintenance of the muscle tissue during ageing. The experienced researcher will expand on previous training acquired in San Francisco, USA, and establish a new line of research in the crossroads of two developing fields (quantitative proteomics and biomechanical regulation of tissue homeostasis). This will be a stepping stone for his scientific independence. The host will expand on its expertise on developmental regulation of muscle formation and benefit from the expertise of the candidate in the biology of ageing and homeostasis. A precise understanding of mechanisms that control homeostatic replacement of damaged proteins in muscle fibers should foster interventions aimed at maintenance of muscle capacity in older individuals and thus, an important step towards healthy ageing.

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  • Funder: EC Project Code: 101044892
    Overall Budget: 1,999,230 EURFunder Contribution: 1,999,230 EUR

    If the f-elements; rare earths and actinides, have many applications in various fields (catalysis, materials for optics, for magnetism, for energy and quantum technologies), major fundamental questions yet remain to be discovered. The nature of the interactions between the f orbitals, which have a low radial extension, and their surroundings is still in question. Indeed, if the buried-character of f-electrons confers their compounds with some of their properties, this particularly harms the description of covalent bonds of φ-symmetry. More specifically, the interaction of two φ-symmetry metallic orbitals, which would lead to the description of φ-bonds, is sorely lacking in the landscape of molecular chemistry. In order to exacerbate the interactions with f- orbitals, we propose to use the argument of symmetry, locking the f orbitals in an ideal configuration, which will make the description of φ-interactions easier to study. We propose to use original large aromatic ligands in order to synthesize compounds of high symmetry. This approach notably differs from the current one, which aims to sterically hinder conventional ligands with large substituents. Once the symmetry is locked, we will vary the electron count and the redox state, as well as the ligand field by modulating the 4f- or 5f-ion used, including transuranic elements. The organometallic synthesis of the these original 4f- and 5f-compounds will be followed by experimental electronic density studies as well as adapted spectroscopy, which will shed light on the interactions of φ−symmetry. Unusual radioelements, uranium and more classical rare earth metal ions will thus lead to an overall assessment of the necessary requirements to enhance the interactions and move towards molecules containing several f-metal ions and a small intermetallic distance. The redox and physical properties of the latter compounds will be engineered with the aim of forming molecules containing metal-metal interactions of φ-symmetry.

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