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description Publicationkeyboard_double_arrow_right Article 2015 Netherlands English Publicly fundedFunded by:EC | FOOD4MEEC| FOOD4MEIn e-health intervention studies, there are concerns about the reliability of internet-based, self-reported (SR) data and about the potential for identity fraud. This study introduced and tested a novel procedure for assessing the validity of internet-based, SR identity and validated anthropometric and demographic data via measurements performed face-to-face in a validation study (VS). Participants (n = 140) from seven European countries, participating in the Food4Me intervention study which aimed to test the efficacy of personalised nutrition approaches delivered via the internet, were invited to take part in the VS. Participants visited a research centre in each country within 2 weeks of providing SR data via the internet. Participants received detailed instructions on how to perform each measurement. Individual’s identity was checked visually and by repeated collection and analysis of buccal cell DNA for 33 genetic variants. Validation of identity using genomic information showed perfect concordance between SR and VS. Similar results were found for demographic data (age and sex verification). We observed strong intra-class correlation coefficients between SR and VS for anthropometric data (height 0.990, weight 0.994 and BMI 0.983). However, internet-based SR weight was under-reported (Δ −0.70 kg [−3.6 to 2.1], p < 0.0001) and, therefore, BMI was lower for SR data (Δ −0.29 kg m−2 [−1.5 to 1.0], p < 0.0001). BMI classification was correct in 93 % of cases. We demonstrate the utility of genotype information for detection of possible identity fraud in e-health studies and confirm the reliability of internet-based, SR anthropometric and demographic data collected in the Food4Me study. Trial registration: NCT01530139 (http://clinicaltrials.gov/show/NCT01530139© 2015, European Union.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dris___00893::a187988ddb1a0e74eccd8da1c73feef4&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Doctoral thesis , Thesis 2021 NetherlandsPublisher:University of Maastricht Funded by:EC | FOOD4MEEC| FOOD4MEAuthors: Marsaux, C.F.M.;Marsaux, C.F.M.;OD-Maastricht Univer... arrow_drop_down OD-Maastricht University | MUMC+ Research Information; NARCIS; Maastricht University | MUMC+ Research InformationDoctoral thesis . Thesis . 2021 . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.26481/dis.20160420cm&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert OD-Maastricht Univer... arrow_drop_down OD-Maastricht University | MUMC+ Research Information; NARCIS; Maastricht University | MUMC+ Research InformationDoctoral thesis . Thesis . 2021 . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.26481/dis.20160420cm&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2014 France, Netherlands, FrancePublisher:Oxford University Press (OUP) Funded by:EC | MEDSEAEC| MEDSEALaure Maugendre; Jean-Pierre Gattuso; Justine Louis; A. de Kluijver; Sophie Marro; Karline Soetaert; Frédéric Gazeau;AbstractThe effect of ocean warming and acidification was investigated on a natural plankton assemblage from an oligotrophic area, the bay of Villefranche (NW Mediterranean Sea). The assemblage was sampled in March 2012 and exposed to the following four treatments for 12 days: control (∼360 μatm, 14°C), elevated pCO2 (∼610 μatm, 14°C), elevated temperature (∼410 μatm, 17°C), and elevated pCO2 and temperature (∼690 μatm, 17°C). Nutrients were already depleted at the beginning of the experiment and the concentrations of chlorophyll a (chl a), heterotrophic prokaryotes and viruses decreased, under all treatments, throughout the experiment. There were no statistically significant effects of ocean warming and acidification, whether in isolation or combined, on the concentrations of nutrients, particulate organic matter, chl a and most of the photosynthetic pigments. Furthermore, 13C labelling showed that the carbon transfer rates from 13C-sodium bicarbonate into particulate organic carbon were not affected by seawater warming nor acidification. Rates of gross primary production followed the general decreasing trend of chl a concentrations and were significantly higher under elevated temperature, an effect exacerbated when combined to elevated pCO2 level. In contrast to the other algal groups, the picophytoplankton population (cyanobacteria, mostly Synechococcus) increased throughout the experiment and was more abundant in the warmer treatment though to a lesser extent when combined to high pCO2 level. These results suggest that under nutrient-depleted conditions in the Mediterranean Sea, ocean acidification has a very limited impact on the plankton community and that small species will benefit from warming with a potential decrease of the export and energy transfer to higher trophic levels.
ICES Journal of Mari... arrow_drop_down ICES Journal of Marine Science; NARCISOther literature type . Article . 2015 . 2014 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/icesjms/fsu161&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 26 citations 26 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert ICES Journal of Mari... arrow_drop_down ICES Journal of Marine Science; NARCISOther literature type . Article . 2015 . 2014 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/icesjms/fsu161&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2014 NetherlandsPublisher:American Meteorological Society Funded by:FCT | H21, EC | EUCLIPSEFCT| H21 ,EC| EUCLIPSEAuthors: J. J. van der Dussen; S. R. de Roode; A. P. Siebesma;J. J. van der Dussen; S. R. de Roode; A. P. Siebesma;Abstract The relationship between the inversion stability and the liquid water path (LWP) tendency of a vertically well-mixed, adiabatic stratocumulus cloud layer is investigated in this study through the analysis of the budget equation for the LWP. The LWP budget is mainly determined by the turbulent fluxes of heat and moisture at the top and the base of the cloud layer, as well as by the source terms due to radiation and precipitation. Through substitution of the inversion stability parameter κ into the budget equation, it immediately follows that the LWP tendency will become negative for increasing values of κ due to the entrainment of increasingly dry air. Large κ values are therefore associated with strong cloud thinning. Using the steady-state solution for the LWP, an equilibrium value κeq is formulated, beyond which the stratocumulus cloud will thin. The Second Dynamics and Chemistry of Marine Stratocumulus field study (DYCOMS-II) is used to illustrate that, depending mainly on the magnitude of the moisture flux at cloud base, stratocumulus clouds can persist well within the buoyancy reversal regime.
NARCIS; TU Delft Rep... arrow_drop_down NARCIS; TU Delft RepositoryArticle . 2014Journal of the Atmospheric Sciences; NARCISArticle . 2014 . Peer-reviewedJournal of the Atmospheric SciencesOther literature type . Article . 2014add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1175/jas-d-13-0114.1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 36 citations 36 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 14visibility views 14 download downloads 94 Powered bymore_vert NARCIS; TU Delft Rep... arrow_drop_down NARCIS; TU Delft RepositoryArticle . 2014Journal of the Atmospheric Sciences; NARCISArticle . 2014 . Peer-reviewedJournal of the Atmospheric SciencesOther literature type . Article . 2014add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1175/jas-d-13-0114.1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 Germany, Germany, NetherlandsPublisher:American Geophysical Union (AGU) Funded by:EC | EPOCA, EC | NEWLOG, EC | MEDSEAEC| EPOCA ,EC| NEWLOG ,EC| MEDSEAKeul; N.; Langer; G.; de Nooijer; L. J.; Nehrke; G.; Reichart; G. J. and Bijma; J;doi: 10.1029/2012gc004330
handle: 1874/288847
The chemical and isotopic composition of foraminiferal shells (so‐called proxies) reflects the physicochemical properties of the seawater. In current day paleoclimate research, the reconstruction of past seawater carbonate system to infer atmospheric CO2 concentrations is one of the most pressing challenges, and a variety of proxies have been investigated, such as foraminiferal U/Ca. Since in natural seawater and traditional CO2 perturbation experiments the carbonate system parameters covary, it is not possible to determine the parameter of the carbonate system causing, e.g., changes in U/Ca, complicating the use of the latter as a carbonate system proxy. We overcome this problem by culturing the benthic foraminifer Ammonia sp. at a range of carbonate chemistry manipulation treatments. Shell U/Ca values were determined to test sensitivity of U incorporation to various parameters of the carbonate system. We argue that is the parameter affecting the U/Ca ratio and consequently, the partitioning coefficient for U in Ammonia sp., DU. We can confirm the strong potential of foraminiferal U/Ca as a proxy.
NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2013Geochemistry Geophysics Geosystems; NARCISArticle . 2013 . Peer-reviewedLicense: Wiley Online Library User AgreementElectronic Publication Information CenterArticle . 2013Data sources: Electronic Publication Information CenterGeochemistry Geophysics GeosystemsArticle . 2013 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1029/2012gc004330&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 45 citations 45 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2013Geochemistry Geophysics Geosystems; NARCISArticle . 2013 . Peer-reviewedLicense: Wiley Online Library User AgreementElectronic Publication Information CenterArticle . 2013Data sources: Electronic Publication Information CenterGeochemistry Geophysics GeosystemsArticle . 2013 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1029/2012gc004330&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 BelgiumPublisher:Elsevier BV Funded by:EC | BENEFITEC| BENEFITAuthors: Moschouli, Eleni; Murwantara, Raden; Vanelslander, Thierry;Moschouli, Eleni; Murwantara, Raden; Vanelslander, Thierry;handle: 10067/1580080151162165141
Abstract The aim of this research is to identify whether the conditions affecting the performance of European transport infrastructure projects, which are completed before and after the global financial crisis (GFC) (2008), are different. The projects that are tested are 22 European projects that are completed before the financial crisis and 25 European projects that are completed after. The method used is the fuzzy set Qualitative Comparative Analysis (fsQCA). One outcome is tested, being whether or not projects are delivered within the budgeted cost (on/over cost) till their completion. Findings show that after the GFC, the quality of the external environment, in terms of the institutional and the financial-economic context, matters more in order to deliver transport infrastructure projects on cost to completion. This means that transport infrastructure projects’ performance is depending on conditions exogenous to the projects more than before the GFC. The level of the cost of capital of the financing scheme is also an important condition, although for projects completed after the GFC, a low cost of capital can still lead to projects being over cost, when the external environment is unfavourable and the remuneration scheme brings high income risks and low cost coverage. Having a robust business model with respect to reducing costs during the construction phase of the project, which is a key factor based on literature, was found to matter both for the occurrence and non-occurrence of the cost outcome for the projects completed before the crisis, when combined with other conditions, but only for the non-occurrence of the cost outcome for the projects completed after the crisis.
Institutional Reposi... arrow_drop_down Institutional Repository Universiteit AntwerpenOther literature type . Article . 2019Data sources: Institutional Repository Universiteit AntwerpenResearch in Transportation EconomicsArticle . 2019 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.retrec.2019.02.004&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 17 citations 17 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Institutional Reposi... arrow_drop_down Institutional Repository Universiteit AntwerpenOther literature type . Article . 2019Data sources: Institutional Repository Universiteit AntwerpenResearch in Transportation EconomicsArticle . 2019 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.retrec.2019.02.004&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018 Netherlands, United KingdomPublisher:Elsevier BV Funded by:EC | SOLUTIONS, EC | EU-ToxRisk, EC | HBM4EU +2 projectsEC| SOLUTIONS ,EC| EU-ToxRisk ,EC| HBM4EU ,EC| EDC-MixRisk ,EC| EuroMixBopp, Stephanie K; Barouki, Robert; Brack, Werner; Dalla Costa, Silvia; Dorne, Jean-Lou C M; Drakvik, Paula E; Faust, Michael; Karjalainen, Tuomo K; Kephalopoulos, Stylianos; van Klaveren, Jacob; Kolossa-Gehring, Marike; Kortenkamp, Andreas; Lebret, Erik; Lettieri, Teresa; Nørager, Sofie; Rüegg, Joëlle; Tarazona, Jose V; Trier, Xenia; van de Water, Bob; van Gils, Jos; Bergman, Åke; Sub RIVM; dIRAS RA-2;Humans and wildlife are exposed to an intractably large number of different combinations of chemicals via food, water, air, consumer products, and other media and sources. This raises concerns about their impact on public and environmental health. The risk assessment of chemicals for regulatory purposes mainly relies on the assessment of individual chemicals. If exposure to multiple chemicals is considered in a legislative framework, it is usually limited to chemicals falling within this framework and co-exposure to chemicals that are covered by a different regulatory framework is often neglected. Methodologies and guidance for assessing risks from combined exposure to multiple chemicals have been developed for different regulatory sectors, however, a harmonised, consistent approach for performing mixture risk assessments and management across different regulatory sectors is lacking. At the time of this publication, several EU research projects are running, funded by the current European Research and Innovation Programme Horizon 2020 or the Seventh Framework Programme. They aim at addressing knowledge gaps and developing methodologies to better assess chemical mixtures, by generating and making available internal and external exposure data, developing models for exposure assessment, developing tools for in silico and in vitro effect assessment to be applied in a tiered framework and for grouping of chemicals, as well as developing joint epidemiological-toxicological approaches for mixture risk assessment and for prioritising mixtures of concern. The projects EDC-MixRisk, EuroMix, EUToxRisk, HBM4EU and SOLUTIONS have started an exchange between the consortia, European Commission Services and EU Agencies, in order to identify where new methodologies have become available and where remaining gaps need to be further addressed. This paper maps how the different projects contribute to the data needs and assessment methodologies and identifies remaining challenges to be further addressed for the assessment of chemical mixtures. Highlights • Mapping EU funded research projects to different aspects of mixture risk assessment. • Overview of current status and methodological developments • Need to further address data and knowledge gaps overarching different chemical sectors
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6192826Data sources: PubMed CentralEnvironment InternationalOther literature type . Article . 2018 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2018.07.037&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 172 citations 172 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6192826Data sources: PubMed CentralEnvironment InternationalOther literature type . Article . 2018 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envint.2018.07.037&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2012 Belgium, Australia, NetherlandsPublisher:Environmental Health Perspectives Funded by:EC | OBELIX, EC | ENRIECO, EC | CLEAR +1 projectsEC| OBELIX ,EC| ENRIECO ,EC| CLEAR ,EC| ARCRISKEva Govarts; Mark J. Nieuwenhuijsen; Greet Schoeters; Ferran Ballester; K. Bloemen; Michielde de Boer; Cécile Chevrier; Merete Eggesbø; Mònica Guxens; Ursula Krämer; Juliette Legler; David Martinez; Lubica Palkovicova; Evridiki Patelarou; Ulrich Ranft; Arja Rautio; Maria Skaalum Petersen; Rémy Slama; Hein Stigum; Gunnar Toft; Tomas Trnovec; Stéphanie Vandentorren; Pal Weihe; Nynke Weisglas Kuperus; Michael Wilhelm; Jürgen Wittsiepe; Jens Peter Bonde;doi: 10.1289/ehp.1103767
pmid: 21997443
pmc: PMC3279442
handle: 10067/969680151162165141 , 1871/48870
doi: 10.1289/ehp.1103767
pmid: 21997443
pmc: PMC3279442
handle: 10067/969680151162165141 , 1871/48870
Abstract: Objectives: Exposure to high concentrations of persistent organochlorines may cause fetal toxicity, but the evidence at low exposure levels is limited. Large studies with substantial exposure contrasts and appropriate exposure assessment are warranted. Within the framework of the EU (European Union) ENRIECO (ENvironmental Health RIsks in European Birth Cohorts) and EU OBELIX (OBesogenic Endocrine disrupting chemicals: LInking prenatal eXposure to the development of obesity later in life) projects, we examined the hypothesis that the combination of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) adversely affects birth weight. Methods: We used maternal and cord blood and breast milk samples of 7,990 women enrolled in 15 study populations from 12 European birth cohorts from 1990 through 2008. Using identical variable definitions, we performed for each cohort linear regression of birth weight on estimates of cord serum concentration of PCB-153 and p,p´-DDE adjusted for gestational age and a priori selected covariates. We obtained summary estimates by meta-analysis and performed analyses of interactions. Results: The median concentration of cord serum PCB-153 was 140 ng/L (range of cohort medians 20484 ng/L) and that of p,p´-DDE was 528 ng/L (range of cohort medians 501,208 ng/L). Birth weight decreased with increasing cord serum concentration of PCB-153 after adjustment for potential confounders in 12 of 15 study populations. The meta-analysis including all cohorts indicated a birth weight decline of 150 g [95% confidence interval (CI): 250, 50 g] per 1-µg/L increase in PCB-153, an exposure contrast that is close to the range of exposures across the cohorts. A 1-µg/L increase in p,p´-DDE was associated with a 7-g decrease in birth weight (95% CI: 18, 4 g). Conclusions: The findings suggest that low-level exposure to PCB (or correlated exposures) impairs fetal growth, but that exposure to p,p´-DDE does not. The study adds to mounting evidence that low-level exposure to PCBs is inversely associated with fetal growth.
NARCIS arrow_drop_down Europe PubMed CentralArticle . 2011Full-Text: http://europepmc.org/articles/PMC3279442Data sources: PubMed CentralEnvironmental Health PerspectivesOther literature type . Article . 2011 . 2012 . Peer-reviewedInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit AntwerpenInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1103767&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 274 citations 274 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert NARCIS arrow_drop_down Europe PubMed CentralArticle . 2011Full-Text: http://europepmc.org/articles/PMC3279442Data sources: PubMed CentralEnvironmental Health PerspectivesOther literature type . Article . 2011 . 2012 . Peer-reviewedInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit AntwerpenInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1103767&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Doctoral thesis , Thesis 2016 NetherlandsPublisher:Wageningen University and Research Funded by:EC | ParaFishControlEC| ParaFishControlAuthors: Y. Liu;Y. Liu;doi: 10.18174/377064
Y. Liu Prof. dr. F. Govers (promotor); Prof. dr. J.M. Raaijmakers (promotor); Dr. I. de Bruijn (co-promotor); Wageningen University, 13 June 2016, 170 pp. The fish egg microbiome: diversity and activity against the oomycete pathogen Saprolegnia Emerging oomycete pathogens increasingly threaten biodiversity and food security. This thesis describes the study of the microbiome of Atlantic salmon (Salmo salar L.) eggs and analyses of the effects of infections by the oomycete pathogen Saprolegnia on the microbial architecture. A low incidence of Saprolegniosis was correlated with a relatively high abundance and richness of specific commensal Actinobacteria. Among the bacterial community, the isolates Frondihabitans sp. 762G35 (Microbacteriaceae) and Pseudomonas sp. H6 significantly inhibited hyphal attachment of Saprolegnia diclina to live salmon eggs. Chemical profiling showed that these two isolates produce furancarboxylic acid-derived metabolites and a lipopeptide viscosin-like biosurfactant, respectively, which inhibited hyphal growth of S. diclina in vitro. Among the fungal community, the fungal isolates obtained from salmon eggs were closely related to Microdochium lycopodinum/Microdochium phragmitis and Trichoderma viride. Both a quantitative and qualitative difference in the Trichoderma population between Saprolegnia-infected and healthy salmon eggs was observed, which suggested that mycoparasitic Trichoderma species could play a role in Saprolegnia suppression in aquaculture. This research provides a scientific framework for studying the diversity and dynamics of microbial communities to mitigate emerging diseases. The Frondihabitans, Pseudomonas and Trichoderma isolates, and/or their bioactive metabolites, are proposed as effective candidates to control Saprolegniosis.
NARCIS; Research@WUR arrow_drop_down Research@WUR; NARCISOther literature type . Doctoral thesis . Thesis . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down Research@WUR; NARCISOther literature type . Doctoral thesis . Thesis . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Report 2019 NetherlandsPublisher:Stichting Wageningen Research, Wageningen Plant Research, Business unit Open Teelten Funded by:EC | iSQAPEREC| iSQAPERHoek, J.; van den Berg, W.; Wesselink, M.; Sukkel, W.; Mäder, P.; Bünemann, E.; Bongiorno, G.; de Goede, R.; Brussaard, L.; Bai, Z.; Haagsma, W.; Verstegen, H.; Glavan, M.; Ferreira, C.S.; Garcia Orenes, F.; Toth, Z.; Zhang, W.; Fan, H.; Fu, H.; Gao, H.; Xu, M.;doi: 10.18174/472638
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.18174/472638&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article 2015 Netherlands English Publicly fundedFunded by:EC | FOOD4MEEC| FOOD4MEIn e-health intervention studies, there are concerns about the reliability of internet-based, self-reported (SR) data and about the potential for identity fraud. This study introduced and tested a novel procedure for assessing the validity of internet-based, SR identity and validated anthropometric and demographic data via measurements performed face-to-face in a validation study (VS). Participants (n = 140) from seven European countries, participating in the Food4Me intervention study which aimed to test the efficacy of personalised nutrition approaches delivered via the internet, were invited to take part in the VS. Participants visited a research centre in each country within 2 weeks of providing SR data via the internet. Participants received detailed instructions on how to perform each measurement. Individual’s identity was checked visually and by repeated collection and analysis of buccal cell DNA for 33 genetic variants. Validation of identity using genomic information showed perfect concordance between SR and VS. Similar results were found for demographic data (age and sex verification). We observed strong intra-class correlation coefficients between SR and VS for anthropometric data (height 0.990, weight 0.994 and BMI 0.983). However, internet-based SR weight was under-reported (Δ −0.70 kg [−3.6 to 2.1], p < 0.0001) and, therefore, BMI was lower for SR data (Δ −0.29 kg m−2 [−1.5 to 1.0], p < 0.0001). BMI classification was correct in 93 % of cases. We demonstrate the utility of genotype information for detection of possible identity fraud in e-health studies and confirm the reliability of internet-based, SR anthropometric and demographic data collected in the Food4Me study. Trial registration: NCT01530139 (http://clinicaltrials.gov/show/NCT01530139© 2015, European Union.
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For further information contact us at helpdesk@openaire.eu0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=dris___00893::a187988ddb1a0e74eccd8da1c73feef4&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Doctoral thesis , Thesis 2021 NetherlandsPublisher:University of Maastricht Funded by:EC | FOOD4MEEC| FOOD4MEAuthors: Marsaux, C.F.M.;Marsaux, C.F.M.;OD-Maastricht Univer... arrow_drop_down OD-Maastricht University | MUMC+ Research Information; NARCIS; Maastricht University | MUMC+ Research InformationDoctoral thesis . Thesis . 2021 . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.26481/dis.20160420cm&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert OD-Maastricht Univer... arrow_drop_down OD-Maastricht University | MUMC+ Research Information; NARCIS; Maastricht University | MUMC+ Research InformationDoctoral thesis . Thesis . 2021 . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.26481/dis.20160420cm&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2014 France, Netherlands, FrancePublisher:Oxford University Press (OUP) Funded by:EC | MEDSEAEC| MEDSEALaure Maugendre; Jean-Pierre Gattuso; Justine Louis; A. de Kluijver; Sophie Marro; Karline Soetaert; Frédéric Gazeau;AbstractThe effect of ocean warming and acidification was investigated on a natural plankton assemblage from an oligotrophic area, the bay of Villefranche (NW Mediterranean Sea). The assemblage was sampled in March 2012 and exposed to the following four treatments for 12 days: control (∼360 μatm, 14°C), elevated pCO2 (∼610 μatm, 14°C), elevated temperature (∼410 μatm, 17°C), and elevated pCO2 and temperature (∼690 μatm, 17°C). Nutrients were already depleted at the beginning of the experiment and the concentrations of chlorophyll a (chl a), heterotrophic prokaryotes and viruses decreased, under all treatments, throughout the experiment. There were no statistically significant effects of ocean warming and acidification, whether in isolation or combined, on the concentrations of nutrients, particulate organic matter, chl a and most of the photosynthetic pigments. Furthermore, 13C labelling showed that the carbon transfer rates from 13C-sodium bicarbonate into particulate organic carbon were not affected by seawater warming nor acidification. Rates of gross primary production followed the general decreasing trend of chl a concentrations and were significantly higher under elevated temperature, an effect exacerbated when combined to elevated pCO2 level. In contrast to the other algal groups, the picophytoplankton population (cyanobacteria, mostly Synechococcus) increased throughout the experiment and was more abundant in the warmer treatment though to a lesser extent when combined to high pCO2 level. These results suggest that under nutrient-depleted conditions in the Mediterranean Sea, ocean acidification has a very limited impact on the plankton community and that small species will benefit from warming with a potential decrease of the export and energy transfer to higher trophic levels.
ICES Journal of Mari... arrow_drop_down ICES Journal of Marine Science; NARCISOther literature type . Article . 2015 . 2014 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/icesjms/fsu161&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 26 citations 26 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert ICES Journal of Mari... arrow_drop_down ICES Journal of Marine Science; NARCISOther literature type . Article . 2015 . 2014 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/icesjms/fsu161&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2014 NetherlandsPublisher:American Meteorological Society Funded by:FCT | H21, EC | EUCLIPSEFCT| H21 ,EC| EUCLIPSEAuthors: J. J. van der Dussen; S. R. de Roode; A. P. Siebesma;J. J. van der Dussen; S. R. de Roode; A. P. Siebesma;Abstract The relationship between the inversion stability and the liquid water path (LWP) tendency of a vertically well-mixed, adiabatic stratocumulus cloud layer is investigated in this study through the analysis of the budget equation for the LWP. The LWP budget is mainly determined by the turbulent fluxes of heat and moisture at the top and the base of the cloud layer, as well as by the source terms due to radiation and precipitation. Through substitution of the inversion stability parameter κ into the budget equation, it immediately follows that the LWP tendency will become negative for increasing values of κ due to the entrainment of increasingly dry air. Large κ values are therefore associated with strong cloud thinning. Using the steady-state solution for the LWP, an equilibrium value κeq is formulated, beyond which the stratocumulus cloud will thin. The Second Dynamics and Chemistry of Marine Stratocumulus field study (DYCOMS-II) is used to illustrate that, depending mainly on the magnitude of the moisture flux at cloud base, stratocumulus clouds can persist well within the buoyancy reversal regime.
NARCIS; TU Delft Rep... arrow_drop_down NARCIS; TU Delft RepositoryArticle . 2014Journal of the Atmospheric Sciences; NARCISArticle . 2014 . Peer-reviewedJournal of the Atmospheric SciencesOther literature type . Article . 2014add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1175/jas-d-13-0114.1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 36 citations 36 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!visibility 14visibility views 14 download downloads 94 Powered bymore_vert NARCIS; TU Delft Rep... arrow_drop_down NARCIS; TU Delft RepositoryArticle . 2014Journal of the Atmospheric Sciences; NARCISArticle . 2014 . Peer-reviewedJournal of the Atmospheric SciencesOther literature type . Article . 2014add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1175/jas-d-13-0114.1&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2013 Germany, Germany, NetherlandsPublisher:American Geophysical Union (AGU) Funded by:EC | EPOCA, EC | NEWLOG, EC | MEDSEAEC| EPOCA ,EC| NEWLOG ,EC| MEDSEAKeul; N.; Langer; G.; de Nooijer; L. J.; Nehrke; G.; Reichart; G. J. and Bijma; J;doi: 10.1029/2012gc004330
handle: 1874/288847
The chemical and isotopic composition of foraminiferal shells (so‐called proxies) reflects the physicochemical properties of the seawater. In current day paleoclimate research, the reconstruction of past seawater carbonate system to infer atmospheric CO2 concentrations is one of the most pressing challenges, and a variety of proxies have been investigated, such as foraminiferal U/Ca. Since in natural seawater and traditional CO2 perturbation experiments the carbonate system parameters covary, it is not possible to determine the parameter of the carbonate system causing, e.g., changes in U/Ca, complicating the use of the latter as a carbonate system proxy. We overcome this problem by culturing the benthic foraminifer Ammonia sp. at a range of carbonate chemistry manipulation treatments. Shell U/Ca values were determined to test sensitivity of U incorporation to various parameters of the carbonate system. We argue that is the parameter affecting the U/Ca ratio and consequently, the partitioning coefficient for U in Ammonia sp., DU. We can confirm the strong potential of foraminiferal U/Ca as a proxy.
NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2013Geochemistry Geophysics Geosystems; NARCISArticle . 2013 . Peer-reviewedLicense: Wiley Online Library User AgreementElectronic Publication Information CenterArticle . 2013Data sources: Electronic Publication Information CenterGeochemistry Geophysics GeosystemsArticle . 2013 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 45 citations 45 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert NARCIS; Utrecht Univ... arrow_drop_down NARCIS; Utrecht University RepositoryArticle . 2013Geochemistry Geophysics Geosystems; NARCISArticle . 2013 . Peer-reviewedLicense: Wiley Online Library User AgreementElectronic Publication Information CenterArticle . 2013Data sources: Electronic Publication Information CenterGeochemistry Geophysics GeosystemsArticle . 2013 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1029/2012gc004330&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 BelgiumPublisher:Elsevier BV Funded by:EC | BENEFITEC| BENEFITAuthors: Moschouli, Eleni; Murwantara, Raden; Vanelslander, Thierry;Moschouli, Eleni; Murwantara, Raden; Vanelslander, Thierry;handle: 10067/1580080151162165141
Abstract The aim of this research is to identify whether the conditions affecting the performance of European transport infrastructure projects, which are completed before and after the global financial crisis (GFC) (2008), are different. The projects that are tested are 22 European projects that are completed before the financial crisis and 25 European projects that are completed after. The method used is the fuzzy set Qualitative Comparative Analysis (fsQCA). One outcome is tested, being whether or not projects are delivered within the budgeted cost (on/over cost) till their completion. Findings show that after the GFC, the quality of the external environment, in terms of the institutional and the financial-economic context, matters more in order to deliver transport infrastructure projects on cost to completion. This means that transport infrastructure projects’ performance is depending on conditions exogenous to the projects more than before the GFC. The level of the cost of capital of the financing scheme is also an important condition, although for projects completed after the GFC, a low cost of capital can still lead to projects being over cost, when the external environment is unfavourable and the remuneration scheme brings high income risks and low cost coverage. Having a robust business model with respect to reducing costs during the construction phase of the project, which is a key factor based on literature, was found to matter both for the occurrence and non-occurrence of the cost outcome for the projects completed before the crisis, when combined with other conditions, but only for the non-occurrence of the cost outcome for the projects completed after the crisis.
Institutional Reposi... arrow_drop_down Institutional Repository Universiteit AntwerpenOther literature type . Article . 2019Data sources: Institutional Repository Universiteit AntwerpenResearch in Transportation EconomicsArticle . 2019 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 17 citations 17 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Institutional Reposi... arrow_drop_down Institutional Repository Universiteit AntwerpenOther literature type . Article . 2019Data sources: Institutional Repository Universiteit AntwerpenResearch in Transportation EconomicsArticle . 2019 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2018 Netherlands, United KingdomPublisher:Elsevier BV Funded by:EC | SOLUTIONS, EC | EU-ToxRisk, EC | HBM4EU +2 projectsEC| SOLUTIONS ,EC| EU-ToxRisk ,EC| HBM4EU ,EC| EDC-MixRisk ,EC| EuroMixBopp, Stephanie K; Barouki, Robert; Brack, Werner; Dalla Costa, Silvia; Dorne, Jean-Lou C M; Drakvik, Paula E; Faust, Michael; Karjalainen, Tuomo K; Kephalopoulos, Stylianos; van Klaveren, Jacob; Kolossa-Gehring, Marike; Kortenkamp, Andreas; Lebret, Erik; Lettieri, Teresa; Nørager, Sofie; Rüegg, Joëlle; Tarazona, Jose V; Trier, Xenia; van de Water, Bob; van Gils, Jos; Bergman, Åke; Sub RIVM; dIRAS RA-2;Humans and wildlife are exposed to an intractably large number of different combinations of chemicals via food, water, air, consumer products, and other media and sources. This raises concerns about their impact on public and environmental health. The risk assessment of chemicals for regulatory purposes mainly relies on the assessment of individual chemicals. If exposure to multiple chemicals is considered in a legislative framework, it is usually limited to chemicals falling within this framework and co-exposure to chemicals that are covered by a different regulatory framework is often neglected. Methodologies and guidance for assessing risks from combined exposure to multiple chemicals have been developed for different regulatory sectors, however, a harmonised, consistent approach for performing mixture risk assessments and management across different regulatory sectors is lacking. At the time of this publication, several EU research projects are running, funded by the current European Research and Innovation Programme Horizon 2020 or the Seventh Framework Programme. They aim at addressing knowledge gaps and developing methodologies to better assess chemical mixtures, by generating and making available internal and external exposure data, developing models for exposure assessment, developing tools for in silico and in vitro effect assessment to be applied in a tiered framework and for grouping of chemicals, as well as developing joint epidemiological-toxicological approaches for mixture risk assessment and for prioritising mixtures of concern. The projects EDC-MixRisk, EuroMix, EUToxRisk, HBM4EU and SOLUTIONS have started an exchange between the consortia, European Commission Services and EU Agencies, in order to identify where new methodologies have become available and where remaining gaps need to be further addressed. This paper maps how the different projects contribute to the data needs and assessment methodologies and identifies remaining challenges to be further addressed for the assessment of chemical mixtures. Highlights • Mapping EU funded research projects to different aspects of mixture risk assessment. • Overview of current status and methodological developments • Need to further address data and knowledge gaps overarching different chemical sectors
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6192826Data sources: PubMed CentralEnvironment InternationalOther literature type . Article . 2018 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 172 citations 172 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2018Full-Text: http://europepmc.org/articles/PMC6192826Data sources: PubMed CentralEnvironment InternationalOther literature type . Article . 2018 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2012 Belgium, Australia, NetherlandsPublisher:Environmental Health Perspectives Funded by:EC | OBELIX, EC | ENRIECO, EC | CLEAR +1 projectsEC| OBELIX ,EC| ENRIECO ,EC| CLEAR ,EC| ARCRISKEva Govarts; Mark J. Nieuwenhuijsen; Greet Schoeters; Ferran Ballester; K. Bloemen; Michielde de Boer; Cécile Chevrier; Merete Eggesbø; Mònica Guxens; Ursula Krämer; Juliette Legler; David Martinez; Lubica Palkovicova; Evridiki Patelarou; Ulrich Ranft; Arja Rautio; Maria Skaalum Petersen; Rémy Slama; Hein Stigum; Gunnar Toft; Tomas Trnovec; Stéphanie Vandentorren; Pal Weihe; Nynke Weisglas Kuperus; Michael Wilhelm; Jürgen Wittsiepe; Jens Peter Bonde;doi: 10.1289/ehp.1103767
pmid: 21997443
pmc: PMC3279442
handle: 10067/969680151162165141 , 1871/48870
doi: 10.1289/ehp.1103767
pmid: 21997443
pmc: PMC3279442
handle: 10067/969680151162165141 , 1871/48870
Abstract: Objectives: Exposure to high concentrations of persistent organochlorines may cause fetal toxicity, but the evidence at low exposure levels is limited. Large studies with substantial exposure contrasts and appropriate exposure assessment are warranted. Within the framework of the EU (European Union) ENRIECO (ENvironmental Health RIsks in European Birth Cohorts) and EU OBELIX (OBesogenic Endocrine disrupting chemicals: LInking prenatal eXposure to the development of obesity later in life) projects, we examined the hypothesis that the combination of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE) adversely affects birth weight. Methods: We used maternal and cord blood and breast milk samples of 7,990 women enrolled in 15 study populations from 12 European birth cohorts from 1990 through 2008. Using identical variable definitions, we performed for each cohort linear regression of birth weight on estimates of cord serum concentration of PCB-153 and p,p´-DDE adjusted for gestational age and a priori selected covariates. We obtained summary estimates by meta-analysis and performed analyses of interactions. Results: The median concentration of cord serum PCB-153 was 140 ng/L (range of cohort medians 20484 ng/L) and that of p,p´-DDE was 528 ng/L (range of cohort medians 501,208 ng/L). Birth weight decreased with increasing cord serum concentration of PCB-153 after adjustment for potential confounders in 12 of 15 study populations. The meta-analysis including all cohorts indicated a birth weight decline of 150 g [95% confidence interval (CI): 250, 50 g] per 1-µg/L increase in PCB-153, an exposure contrast that is close to the range of exposures across the cohorts. A 1-µg/L increase in p,p´-DDE was associated with a 7-g decrease in birth weight (95% CI: 18, 4 g). Conclusions: The findings suggest that low-level exposure to PCB (or correlated exposures) impairs fetal growth, but that exposure to p,p´-DDE does not. The study adds to mounting evidence that low-level exposure to PCBs is inversely associated with fetal growth.
NARCIS arrow_drop_down Europe PubMed CentralArticle . 2011Full-Text: http://europepmc.org/articles/PMC3279442Data sources: PubMed CentralEnvironmental Health PerspectivesOther literature type . Article . 2011 . 2012 . Peer-reviewedInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit AntwerpenInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 274 citations 274 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert NARCIS arrow_drop_down Europe PubMed CentralArticle . 2011Full-Text: http://europepmc.org/articles/PMC3279442Data sources: PubMed CentralEnvironmental Health PerspectivesOther literature type . Article . 2011 . 2012 . Peer-reviewedInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit AntwerpenInstitutional Repository Universiteit AntwerpenArticle . 2012Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1289/ehp.1103767&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Doctoral thesis , Thesis 2016 NetherlandsPublisher:Wageningen University and Research Funded by:EC | ParaFishControlEC| ParaFishControlAuthors: Y. Liu;Y. Liu;doi: 10.18174/377064
Y. Liu Prof. dr. F. Govers (promotor); Prof. dr. J.M. Raaijmakers (promotor); Dr. I. de Bruijn (co-promotor); Wageningen University, 13 June 2016, 170 pp. The fish egg microbiome: diversity and activity against the oomycete pathogen Saprolegnia Emerging oomycete pathogens increasingly threaten biodiversity and food security. This thesis describes the study of the microbiome of Atlantic salmon (Salmo salar L.) eggs and analyses of the effects of infections by the oomycete pathogen Saprolegnia on the microbial architecture. A low incidence of Saprolegniosis was correlated with a relatively high abundance and richness of specific commensal Actinobacteria. Among the bacterial community, the isolates Frondihabitans sp. 762G35 (Microbacteriaceae) and Pseudomonas sp. H6 significantly inhibited hyphal attachment of Saprolegnia diclina to live salmon eggs. Chemical profiling showed that these two isolates produce furancarboxylic acid-derived metabolites and a lipopeptide viscosin-like biosurfactant, respectively, which inhibited hyphal growth of S. diclina in vitro. Among the fungal community, the fungal isolates obtained from salmon eggs were closely related to Microdochium lycopodinum/Microdochium phragmitis and Trichoderma viride. Both a quantitative and qualitative difference in the Trichoderma population between Saprolegnia-infected and healthy salmon eggs was observed, which suggested that mycoparasitic Trichoderma species could play a role in Saprolegnia suppression in aquaculture. This research provides a scientific framework for studying the diversity and dynamics of microbial communities to mitigate emerging diseases. The Frondihabitans, Pseudomonas and Trichoderma isolates, and/or their bioactive metabolites, are proposed as effective candidates to control Saprolegniosis.
NARCIS; Research@WUR arrow_drop_down Research@WUR; NARCISOther literature type . Doctoral thesis . Thesis . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.18174/377064&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down Research@WUR; NARCISOther literature type . Doctoral thesis . Thesis . 2016 . Peer-reviewedadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.18174/377064&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Report 2019 NetherlandsPublisher:Stichting Wageningen Research, Wageningen Plant Research, Business unit Open Teelten Funded by:EC | iSQAPEREC| iSQAPERHoek, J.; van den Berg, W.; Wesselink, M.; Sukkel, W.; Mäder, P.; Bünemann, E.; Bongiorno, G.; de Goede, R.; Brussaard, L.; Bai, Z.; Haagsma, W.; Verstegen, H.; Glavan, M.; Ferreira, C.S.; Garcia Orenes, F.; Toth, Z.; Zhang, W.; Fan, H.; Fu, H.; Gao, H.; Xu, M.;doi: 10.18174/472638
NARCIS; Research@WUR arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.18174/472638&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.18174/472638&type=result"></script>'); --> </script>
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