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description Publicationkeyboard_double_arrow_right Article 2021 FrancePublisher:MDPI AG Funded by:SNSF | Epidemiology and determin..., SNSF | Risk factors for catheter...SNSF| Epidemiology and determinants of catheter-related and hospital-acquired bloodstream infections: from a large university hospital to a global picture ,SNSF| Risk factors for catheter-related infections in Intensive Care Units. Closing the knowledge gap with data from four randomized trials.Moreno Ursino; Claire Dupuis; Niccolò Buetti; Etienne de Montmollin; Lila Bouadma; Dany Golgran-Toledano; Stéphane Ruckly; Mathilde Neuville; Yves Cohen; Bruno Mourvillier; Bertrand Souweine; Marc Gainnier; Virginie Laurent; Nicolas Terzi; Shidasp Shiami; Jean Reignier; Corinne Alberti; Jean-François Timsit;International audience; The mortality of COVID-19 patients in the intensive care unit (ICU) is influenced by their state at admission. We aimed to model COVID-19 acute respiratory distress syndrome state transitions from ICU admission to day 60 outcome and to evaluate possible prognostic factors. We analyzed a prospective French database that includes critically ill COVID-19 patients. A six-state multistate model was built and 17 transitions were analyzed either using a non-parametric approach or a Cox proportional hazard model. Corticosteroids and IL-antagonists (tocilizumab and anakinra) effects were evaluated using G-computation. We included 382 patients in the analysis: 243 patients were admitted to the ICU with non-invasive ventilation, 116 with invasive mechanical ventilation, and 23 with extracorporeal membrane oxygenation. The predicted 60-day mortality was 25.9% (95% CI: 21.8%–30.0%), 44.7% (95% CI: 48.8%–50.6%), and 59.2% (95% CI: 49.4%–69.0%) for a patient admitted in these three states, respectively. Corticosteroids decreased the risk of being invasively ventilated (hazard ratio (HR) 0.59, 95% CI: 0.39–0.90) and IL-antagonists increased the probability of being successfully extubated (HR 1.8, 95% CI: 1.02–3.17). Antiviral drugs did not impact any transition. In conclusion, we observed that the day-60 outcome in COVID-19 patients is highly dependent on the first ventilation state upon ICU admission. Moreover, we illustrated that corticosteroid and IL-antagonists may influence the intubation duration.
Journal of Clinical ... arrow_drop_down Journal of Clinical MedicineOther literature type . Article . 2021 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/2077-0383/10/3/544/pdfEurope PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7867229Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/jcm10030544&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 10 citations 10 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Journal of Clinical ... arrow_drop_down Journal of Clinical MedicineOther literature type . Article . 2021 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/2077-0383/10/3/544/pdfEurope PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7867229Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/jcm10030544&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015 Switzerland, France, Germany Funded by:EC | I-FIVE, SNSF | Viral triggers and gray m..., EC | GUT TC PHENOTYPESEC| I-FIVE ,SNSF| Viral triggers and gray matter involvement in multiple sclerosis ,EC| GUT TC PHENOTYPESAuthors: Bhattacharya, Anannya; Hegazy, Ahmed N; Deigendesch, Nikolaus; Kosack, Lindsay; +21 AuthorsBhattacharya, Anannya; Hegazy, Ahmed N; Deigendesch, Nikolaus; Kosack, Lindsay; Cupovic, Jovana; Kandasamy, Richard K; Hildebrandt, Andrea; Merkler, Doron; Kühl, Anja A; Vilagos, Bojan; Schliehe, Christopher; Panse, Isabel; Khamina, Kseniya; Baazim, Hatoon; Arnold, Isabelle; Flatz, Lukas; Xu, Haifeng C; Lang, Philipp A; Aderem, Alan; Takaoka, Akinori; Superti-Furga, Giulio; Colinge, Jacques; Ludewig, Burkhard; Löhning, Max; Bergthaler, Andréas;Summary Tissue damage caused by viral hepatitis is a major cause of morbidity and mortality worldwide. Using a mouse model of viral hepatitis, we identified virus-induced early transcriptional changes in the redox pathways in the liver, including downregulation of superoxide dismutase 1 (Sod1). Sod1−/− mice exhibited increased inflammation and aggravated liver damage upon viral infection, which was independent of T and NK cells and could be ameliorated by antioxidant treatment. Type I interferon (IFN-I) led to a downregulation of Sod1 and caused oxidative liver damage in Sod1−/− and wild-type mice. Genetic and pharmacological ablation of the IFN-I signaling pathway protected against virus-induced liver damage. These results delineate IFN-I mediated oxidative stress as a key mediator of virus-induced liver damage and describe a mechanism of innate-immunity-driven pathology, linking IFN-I signaling with antioxidant host defense and infection-associated tissue damage. Video Abstract Highlights • Viral infection leads to redox dysregulation including the downregulation of SOD1 • Sod1−/− mice exhibit aggravated viral hepatitis, which is rescued by antioxidants • IFN-I signaling via STAT1 drives SOD1 downregulation and early liver damage • Ablation of IFN-I signaling ameliorates viral hepatitis in Sod1−/− and WT mice Bergthaler and colleagues show that superoxide dismutase 1 protects the liver from type I interferon-driven oxidative damage in viral hepatitis. Liver damage was mediated by hepatocyte-intrinsic IFNAR1-STAT1 signaling. Graphical Abstract
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4658338Data sources: PubMed CentralGöttingen Research Online PublicationsArticle . 2018Data sources: Göttingen Research Online PublicationsPublikationenserver der Georg-August-Universität GöttingenArticle . 2015 . Peer-reviewedImmunity; OpenAPC Global InitiativeOther literature type . Article . Conference object . 2015 . Peer-reviewedLicense: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.immuni.2015.10.013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 57 citations 57 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4658338Data sources: PubMed CentralGöttingen Research Online PublicationsArticle . 2018Data sources: Göttingen Research Online PublicationsPublikationenserver der Georg-August-Universität GöttingenArticle . 2015 . Peer-reviewedImmunity; OpenAPC Global InitiativeOther literature type . Article . Conference object . 2015 . Peer-reviewedLicense: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.immuni.2015.10.013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 France, SwitzerlandPublisher:Dewspublication Funded by:SNSF | Framing Environmental Deg...SNSF| Framing Environmental Degradation, Human Mobility and Human Development as a Matter of 'Common Concern'Authors: Elisa Fornalé; Odasso Laura;Elisa Fornalé; Odasso Laura;International audience; Gender, class, ethnicity and generation played a determining role in exposure to the COVID-19 virus and in access to care. This translated into differences in communicability, morbidity and mortality. Migrants and ethnic minorities have been over-represented among serious cases, just as they are often also disproportionately affected during natural disasters and crises. We focus on a segment of vulnerable population defined by the French term ‘inconfinables’. Related to the term ‘confinement’, used in France to mean lockdown, the ‘inconfinables’ are those individuals that, due to personal, socio-economic and administrative factors, may not respect the governmental measures proposed to contain the spread of the pandemic. The article presents an comparative analysis of different approaches implemented at the domestic level (in France and Italy) to gain original insights into the practice of lockdown regimes. These insights are used to explore the nexus between ethnic social inequalities, governmental capacity to ensure effective protection of the whole population and human rights.
Bern Open Repository... arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.33182/ml.v19i6.2225&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert Bern Open Repository... arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.33182/ml.v19i6.2225&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2009 France, SwitzerlandPublisher:EDP Sciences Funded by:SNSF | Animal models for retrovi..., SNSF | Animal models for retrovi...SNSF| Animal models for retroviral infections: how to overcome the infection ,SNSF| Animal models for retroviral infections: how to overcome the infectionMuseux, K; Boretti, Felicitas S; Willi, Barbara; Riond, Barbara; Hoelzle, K; Hoelzle, L E; Wittenbrink, M M; Tasker, S; Wengi, N; Reusch, Claudia E; Lutz, H; Hofmann-Lehmann, R;The natural transmission routes of the three feline haemotropic mycoplasmas - Mycoplasma haemofelis ,' Candidatus Mycoplasma haemominutum', and 'Candidatus Mycoplasma turicensis' (CMt) - are largely unknown. Since CMt has been detected in the saliva of infected cats using PCR, we hypothesised that direct transmission via social or aggressive contact may occur. The aim of this study was to evaluate this transmission route. CMt-positive saliva and blood samples were obtained from three prednisolone- treated specific pathogen-free (SPF) cats that were infected intraperitoneally with CMt. Five SPF cats were inoculated with CMt-positive saliva or blood subcutaneously to mimic cat bites, and five cats were inoculated orally with blood or oronasally with saliva to mimic social contact. Blood samples were monitored for CMt infection using quantitative real-time PCR and for seroconversion using a novel western blot assay. Neither oronasal nor subcutaneous inoculation with CMt-positive saliva led to CMt infection in the recipient cats, as determined by PCR, independent of prior prednisolone treatment. However, when blood containing the same CMt dose was given subcutaneously, 4 of the 5 cats became PCR-positive, while none of the 5 cats inoculated orally with up to 500 lL of CMt-positive blood became PCR-positive. Subsequently, the latter cats were successfully subcutaneously infected with blood. All 13 CMt-exposed cats seroconverted. In conclusion, CMt transmission by social contact seems less likely than transmission by aggressive interaction. The latter transmission may occur if the recipient cat is exposed to blood from an infected cat. haemotropic mycoplasma / transmission / 'Candidatus Mycoplasma turicensis' / real-time TaqMan PCR / seroconversion
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2009Full-Text: http://europepmc.org/articles/PMC2701178Data sources: PubMed CentralZurich Open Repository and ArchiveOther literature type . 2009Mémoires en Sciences de l'Information et de la CommunicationArticle . 2009Full-Text: https://hal.science/hal-00903107/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/vetres/2009028&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 84 citations 84 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2009Full-Text: http://europepmc.org/articles/PMC2701178Data sources: PubMed CentralZurich Open Repository and ArchiveOther literature type . 2009Mémoires en Sciences de l'Information et de la CommunicationArticle . 2009Full-Text: https://hal.science/hal-00903107/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/vetres/2009028&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2020Embargo end date: 01 Jan 2020 Spain, France, Finland, Spain, Portugal, Switzerland, Ireland, CyprusPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:SNSF | Promoting Mental Health a..., SNSF | Effects of Psychological ...SNSF| Promoting Mental Health and Prosocial Behaviors: Harnessing New Technologies for Therapy and Training in Real-Life Environments ,SNSF| Effects of Psychological Flexibility in Social Context: A Multi-Level ApproachGloster, A.T.; Lamnisos, D.; Lubenko, J.; Presti, G.; Squatrito, V.; Constantinou, M.; Nicolaou, C.; Papacostas, S.; Aydin, G.; Chong, Y.Y.; Chien, W.T.; Cheng, H.Y.; Ruiz, F.J.; Garcia-Martin, M.B.; Obando-Posada, D.P.; Segura-Vargas, M.A.; Vasiliou, V.S.; McHugh, L.; Höfer, S.; Baban, A.; Neto, D.D.; da Silva, A.N.; Monestès, J.L.; Alvarez-Galvez, J.; Paez-Blarrina, M.; Montesinos, F.; Valdivia-Salas, S.; Ori, D.; Kleszcz, B.; Lappalainen, R.; Ivanovic, I.; Gosar, D.; Dionne, F.; Merwin, R.M.; Kassianos, A.P.; Karekla, M.;Background The COVID-19 pandemic triggered vast governmental lockdowns. The impact of these lockdowns on mental health is inadequately understood. On the one hand such drastic changes in daily routines could be detrimental to mental health. On the other hand, it might not be experienced negatively, especially because the entire population was affected. Methods The aim of this study was to determine mental health outcomes during pandemic induced lockdowns and to examine known predictors of mental health outcomes. We therefore surveyed n = 9, 565 people from 78 countries and 18 languages. Outcomes assessed were stress, depression, affect, and wellbeing. Predictors included country, sociodemographic factors, lockdown characteristics, social factors, and psychological factors. Results Results indicated that on average about 10% of the sample was languishing from low levels of mental health and about 50% had only moderate mental health. Importantly, three consistent predictors of mental health emerged: social support, education level, and psychologically flexible (vs. rigid) responding. Poorer outcomes were most strongly predicted by a worsening of finances and not having access to basic supplies. Conclusions These results suggest that on whole, respondents were moderately mentally healthy at the time of a population-wide lockdown. The highest level of mental health difficulties were found in approximately 10% of the population. Findings suggest that public health initiatives should target people without social support and those whose finances worsen as a result of the lockdown. Interventions that promote psychological flexibility may mitigate the impact of the pandemic.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7774914Data sources: PubMed CentralRepositorio de Objetos de Docencia e Investigación de la Universidad de CádizArticle . 2020License: CC BYJyväskylä University Digital ArchiveArticle . 2020 . Peer-reviewedLicense: CC BYData sources: Jyväskylä University Digital ArchiveCork Open Research Archive (CORA)Article . 2020License: CC BYData sources: Cork Open Research Archive (CORA)Recolector de Ciencia Abierta, RECOLECTA; Digital Repository of University of ZaragozaArticle . 2020License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5451/unibas-ep81681&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 131 citations 131 popularity Top 1% influence Top 10% impulse Top 0.1% Powered by BIP!visibility 119visibility views 119 download downloads 112 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7774914Data sources: PubMed CentralRepositorio de Objetos de Docencia e Investigación de la Universidad de CádizArticle . 2020License: CC BYJyväskylä University Digital ArchiveArticle . 2020 . Peer-reviewedLicense: CC BYData sources: Jyväskylä University Digital ArchiveCork Open Research Archive (CORA)Article . 2020License: CC BYData sources: Cork Open Research Archive (CORA)Recolector de Ciencia Abierta, RECOLECTA; Digital Repository of University of ZaragozaArticle . 2020License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5451/unibas-ep81681&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2010 United Kingdom, FrancePublisher:Elsevier BV Funded by:SNSF | The role of innate recept..., WTSNSF| The role of innate receptors in dendritic cell and B lymphocyte activation ,WTAuthors: Beltramello, Martina; Williams, Katherine L.; Simmons, Cameron P.; Macagno, Annalisa; +13 AuthorsBeltramello, Martina; Williams, Katherine L.; Simmons, Cameron P.; Macagno, Annalisa; Simonelli, Luca; Quyen, Nguyen Than Ha; Sukupolvi-Petty, Soila; Navarro-Sanchez, Erika; Young, Paul R.; de Silva, Aravinda M.; Rey, Félix A.; Varani, Luca; Whitehead, Stephen S; Diamond, Michael S.; Harris, Eva; Lanzavecchia, Antonio; Sallusto, Federica;International audience; Antibodies protect against homologous Dengue virus (DENV) infection but can precipitate severe dengue by promoting heterotypic virus entry via Fcγ receptors (FcγR). We immortalized memory B cells from individuals after primary or secondary infection and analyzed anti-DENV monoclonal antibodies (mAbs) thus generated. MAbs to envelope (E) protein domain III (DIII) were either serotype specific or cross-reactive and potently neutralized DENV infection. DI/DII- or viral membrane protein prM-reactive mAbs neutralized poorly and showed broad cross-reactivity with the four DENV serotypes. All mAbs enhanced infection at subneutralizing concentrations. Three mAbs targeting distinct epitopes on the four DENV serotypes and engineered to prevent FcγR binding did not enhance infection and neutralized DENV in vitro and in vivo as postexposure therapy in a mouse model of lethal DENV infection. Our findings reveal an unexpected degree of cross-reactivity in human antibodies against DENV and illustrate the potential for an antibody-based therapy to control severe dengue.
Cell Host & Microbe arrow_drop_down Oxford University Research Archive; Cell Host & MicrobeOther literature type . Article . 2016 . 2010 . Peer-reviewedLicense: Elsevier Non-Commercialadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.chom.2010.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 509 citations 509 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!more_vert Cell Host & Microbe arrow_drop_down Oxford University Research Archive; Cell Host & MicrobeOther literature type . Article . 2016 . 2010 . Peer-reviewedLicense: Elsevier Non-Commercialadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.chom.2010.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 France, SwitzerlandPublisher:MDPI AG Funded by:EC | GASTRICGLYCOEXPLORER, NIH | UniProt: A centralized pr..., SNSF | A context based knowledge...EC| GASTRICGLYCOEXPLORER ,NIH| UniProt: A centralized protein sequence and function resource ,SNSF| A context based knowledge resource integrating HIV and Mtb molecular biology with host-pathogen and drug-resistance dataAuthors: Philippe Le Mercier; Julien Mariethoz; Josefina Lascano-Maillard; François Bonnardel; +3 AuthorsPhilippe Le Mercier; Julien Mariethoz; Josefina Lascano-Maillard; François Bonnardel; Anne Imberty; Sylvie Ricard-Blum; Frédérique Lisacek;International audience; Evidence of the mediation of glycan molecules in the interaction between viruses and their hosts is accumulating and is now partially reflected in several online databases. Bioinformatics provides convenient and efficient means of searching, visualizing, comparing, and sometimes predicting, interactions in numerous and diverse molecular biology applications related to the-omics fields. As viromics is gaining momentum, bioinformatics support is increasingly needed. We propose a survey of the current resources for searching, visualizing, comparing, and possibly predicting host-virus interactions that integrate the presence and role of glycans. To the best of our knowledge, we have mapped the specialized and general-purpose databases with the appropriate focus. With an illustration of their potential usage, we also discuss the strong and weak points of the current bioinformatics landscape in the context of understanding viral infection and the immune response to it.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6521074Data sources: PubMed CentralMémoires en Sciences de l'Information et de la CommunicationArticle . 2019License: CC BYFull-Text: https://hal.science/hal-02109612/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/v11040374&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 5 citations 5 popularity Average influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6521074Data sources: PubMed CentralMémoires en Sciences de l'Information et de la CommunicationArticle . 2019License: CC BYFull-Text: https://hal.science/hal-02109612/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/v11040374&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article 2014 FrancePublisher:Cold Spring Harbor Laboratory Funded by:SNSF | Regulation of early to la..., EC | MODELISTSNSF| Regulation of early to late endosomal traffic ,EC| MODELISTAuthors: Cossart, Pascale; Helenius, Ari;Cossart, Pascale; Helenius, Ari;International audience; Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant intracellular compartments, they take advantage of the endocytosis machinery and exploit the network of endocytic organelles for penetration into the cytosol or as sites of replication. In this review, we discuss the endocytic entry processes used by viruses and bacteria and compare the strategies used by these dissimilar classes of pathogens.
Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/cshperspect.a016972&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 302 citations 302 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/cshperspect.a016972&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Netherlands, Switzerland, Norway, SwitzerlandPublisher:Springer Science and Business Media LLC Funded by:SNSF | What is Sustainable Inten...SNSF| What is Sustainable Intensification? Operationalizing Sustainable Agricultural Intensification Pathways in Europe (SIPATH)Helfenstein, Julian; Bürgi, Matthias; Debonne, Niels; Dimopoulos, Thymios; Diogo, Vasco; Dramstad, Wenche; Edlinger, Anna; Garcia-Martin, Maria; Hernik, Józef; Kizos, Thanasis; Lausch, Angela; Levers, Christian; Mohr, Franziska; Moreno, Gerardo; Pazur, Robert; Siegrist, Michael; Swart, Rebecca; Thenail, Claudine; Verburg, Peter H.; Williams, Tim G.; Zarina, Anita; Herzog, Felix;pmid: 36017120
pmc: PMC9397162
It has been shown that the COVID-19 pandemic affected some agricultural systems more than others, and even within geographic regions, not all farms were affected to the same extent. To build resilience of agricultural systems to future shocks, it is key to understand which farms were affected and why. In this study, we examined farmers' perceived robustness to COVID-19, a key resilience capacity. We conducted standardized farmer interviews (n = 257) in 15 case study areas across Europe, covering a large range of socio-ecological contexts and farm types. Interviews targeted perceived livelihood impacts of the COVID-19 pandemic on productivity, sales, price, labor availability, and supply chains in 2020, as well as farm(er) characteristics and farm management. Our study corroborates earlier evidence that most farms were not or only slightly affected by the first wave(s) of the pandemic in 2020, and that impacts varied widely by study region. However, a significant minority of farmers across Europe reported that the pandemic was "the worst crisis in a lifetime" (3%) or "the worst crisis in a decade" (7%). Statistical analysis showed that more specialized and intensive farms were more likely to have perceived negative impacts. From a societal perspective, this suggests that highly specialized, intensive farms face higher vulnerability to shocks that affect regional to global supply chains. Supporting farmers in the diversification of their production systems while decreasing dependence on service suppliers and supply chain actors may increase their robustness to future disruptions. Agronomy for Sustainable Development, 42 (5) ISSN:1773-0155 ISSN:1774-0746
NARCIS; Research@WUR arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022Full-Text: https://hal.science/hal-04189033/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s13593-022-00820-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022Full-Text: https://hal.science/hal-04189033/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s13593-022-00820-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2015 Switzerland, FrancePublisher:American Society for Microbiology Funded by:SNSF | Rhinovirus et entérovirus...SNSF| Rhinovirus et entérovirus: déterminants génomiques et phénotypes associésJulien, Lupo; Isabelle, Schuffenecker; Christine, Morel-Baccard; Julie, Bardet; Valérie, Payen; Laurent, Kaiser; Samuel, Constant; Johannes Alexander, Lobrinus; Nathalie, Lin-Marq; Bruno, Lina; Patrice, Morand; Caroline, Tapparel;ABSTRACT We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.
Europe PubMed Centra... arrow_drop_down Journal of Clinical MicrobiologyArticle . 2015 . Peer-reviewedLicense: ASM Journals Non-Commercial TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1128/jcm.03484-14&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 13 citations 13 popularity Average influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Journal of Clinical MicrobiologyArticle . 2015 . Peer-reviewedLicense: ASM Journals Non-Commercial TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article 2021 FrancePublisher:MDPI AG Funded by:SNSF | Epidemiology and determin..., SNSF | Risk factors for catheter...SNSF| Epidemiology and determinants of catheter-related and hospital-acquired bloodstream infections: from a large university hospital to a global picture ,SNSF| Risk factors for catheter-related infections in Intensive Care Units. Closing the knowledge gap with data from four randomized trials.Moreno Ursino; Claire Dupuis; Niccolò Buetti; Etienne de Montmollin; Lila Bouadma; Dany Golgran-Toledano; Stéphane Ruckly; Mathilde Neuville; Yves Cohen; Bruno Mourvillier; Bertrand Souweine; Marc Gainnier; Virginie Laurent; Nicolas Terzi; Shidasp Shiami; Jean Reignier; Corinne Alberti; Jean-François Timsit;International audience; The mortality of COVID-19 patients in the intensive care unit (ICU) is influenced by their state at admission. We aimed to model COVID-19 acute respiratory distress syndrome state transitions from ICU admission to day 60 outcome and to evaluate possible prognostic factors. We analyzed a prospective French database that includes critically ill COVID-19 patients. A six-state multistate model was built and 17 transitions were analyzed either using a non-parametric approach or a Cox proportional hazard model. Corticosteroids and IL-antagonists (tocilizumab and anakinra) effects were evaluated using G-computation. We included 382 patients in the analysis: 243 patients were admitted to the ICU with non-invasive ventilation, 116 with invasive mechanical ventilation, and 23 with extracorporeal membrane oxygenation. The predicted 60-day mortality was 25.9% (95% CI: 21.8%–30.0%), 44.7% (95% CI: 48.8%–50.6%), and 59.2% (95% CI: 49.4%–69.0%) for a patient admitted in these three states, respectively. Corticosteroids decreased the risk of being invasively ventilated (hazard ratio (HR) 0.59, 95% CI: 0.39–0.90) and IL-antagonists increased the probability of being successfully extubated (HR 1.8, 95% CI: 1.02–3.17). Antiviral drugs did not impact any transition. In conclusion, we observed that the day-60 outcome in COVID-19 patients is highly dependent on the first ventilation state upon ICU admission. Moreover, we illustrated that corticosteroid and IL-antagonists may influence the intubation duration.
Journal of Clinical ... arrow_drop_down Journal of Clinical MedicineOther literature type . Article . 2021 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/2077-0383/10/3/544/pdfEurope PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7867229Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/jcm10030544&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 10 citations 10 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Journal of Clinical ... arrow_drop_down Journal of Clinical MedicineOther literature type . Article . 2021 . Peer-reviewedLicense: CC BYFull-Text: http://www.mdpi.com/2077-0383/10/3/544/pdfEurope PubMed CentralArticle . 2021Full-Text: http://europepmc.org/articles/PMC7867229Data sources: PubMed Centraladd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/jcm10030544&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2015 Switzerland, France, Germany Funded by:EC | I-FIVE, SNSF | Viral triggers and gray m..., EC | GUT TC PHENOTYPESEC| I-FIVE ,SNSF| Viral triggers and gray matter involvement in multiple sclerosis ,EC| GUT TC PHENOTYPESAuthors: Bhattacharya, Anannya; Hegazy, Ahmed N; Deigendesch, Nikolaus; Kosack, Lindsay; +21 AuthorsBhattacharya, Anannya; Hegazy, Ahmed N; Deigendesch, Nikolaus; Kosack, Lindsay; Cupovic, Jovana; Kandasamy, Richard K; Hildebrandt, Andrea; Merkler, Doron; Kühl, Anja A; Vilagos, Bojan; Schliehe, Christopher; Panse, Isabel; Khamina, Kseniya; Baazim, Hatoon; Arnold, Isabelle; Flatz, Lukas; Xu, Haifeng C; Lang, Philipp A; Aderem, Alan; Takaoka, Akinori; Superti-Furga, Giulio; Colinge, Jacques; Ludewig, Burkhard; Löhning, Max; Bergthaler, Andréas;Summary Tissue damage caused by viral hepatitis is a major cause of morbidity and mortality worldwide. Using a mouse model of viral hepatitis, we identified virus-induced early transcriptional changes in the redox pathways in the liver, including downregulation of superoxide dismutase 1 (Sod1). Sod1−/− mice exhibited increased inflammation and aggravated liver damage upon viral infection, which was independent of T and NK cells and could be ameliorated by antioxidant treatment. Type I interferon (IFN-I) led to a downregulation of Sod1 and caused oxidative liver damage in Sod1−/− and wild-type mice. Genetic and pharmacological ablation of the IFN-I signaling pathway protected against virus-induced liver damage. These results delineate IFN-I mediated oxidative stress as a key mediator of virus-induced liver damage and describe a mechanism of innate-immunity-driven pathology, linking IFN-I signaling with antioxidant host defense and infection-associated tissue damage. Video Abstract Highlights • Viral infection leads to redox dysregulation including the downregulation of SOD1 • Sod1−/− mice exhibit aggravated viral hepatitis, which is rescued by antioxidants • IFN-I signaling via STAT1 drives SOD1 downregulation and early liver damage • Ablation of IFN-I signaling ameliorates viral hepatitis in Sod1−/− and WT mice Bergthaler and colleagues show that superoxide dismutase 1 protects the liver from type I interferon-driven oxidative damage in viral hepatitis. Liver damage was mediated by hepatocyte-intrinsic IFNAR1-STAT1 signaling. Graphical Abstract
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4658338Data sources: PubMed CentralGöttingen Research Online PublicationsArticle . 2018Data sources: Göttingen Research Online PublicationsPublikationenserver der Georg-August-Universität GöttingenArticle . 2015 . Peer-reviewedImmunity; OpenAPC Global InitiativeOther literature type . Article . Conference object . 2015 . Peer-reviewedLicense: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.immuni.2015.10.013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 57 citations 57 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2015Full-Text: http://europepmc.org/articles/PMC4658338Data sources: PubMed CentralGöttingen Research Online PublicationsArticle . 2018Data sources: Göttingen Research Online PublicationsPublikationenserver der Georg-August-Universität GöttingenArticle . 2015 . Peer-reviewedImmunity; OpenAPC Global InitiativeOther literature type . Article . Conference object . 2015 . Peer-reviewedLicense: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.immuni.2015.10.013&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 France, SwitzerlandPublisher:Dewspublication Funded by:SNSF | Framing Environmental Deg...SNSF| Framing Environmental Degradation, Human Mobility and Human Development as a Matter of 'Common Concern'Authors: Elisa Fornalé; Odasso Laura;Elisa Fornalé; Odasso Laura;International audience; Gender, class, ethnicity and generation played a determining role in exposure to the COVID-19 virus and in access to care. This translated into differences in communicability, morbidity and mortality. Migrants and ethnic minorities have been over-represented among serious cases, just as they are often also disproportionately affected during natural disasters and crises. We focus on a segment of vulnerable population defined by the French term ‘inconfinables’. Related to the term ‘confinement’, used in France to mean lockdown, the ‘inconfinables’ are those individuals that, due to personal, socio-economic and administrative factors, may not respect the governmental measures proposed to contain the spread of the pandemic. The article presents an comparative analysis of different approaches implemented at the domestic level (in France and Italy) to gain original insights into the practice of lockdown regimes. These insights are used to explore the nexus between ethnic social inequalities, governmental capacity to ensure effective protection of the whole population and human rights.
Bern Open Repository... arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.33182/ml.v19i6.2225&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert Bern Open Repository... arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.33182/ml.v19i6.2225&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2009 France, SwitzerlandPublisher:EDP Sciences Funded by:SNSF | Animal models for retrovi..., SNSF | Animal models for retrovi...SNSF| Animal models for retroviral infections: how to overcome the infection ,SNSF| Animal models for retroviral infections: how to overcome the infectionMuseux, K; Boretti, Felicitas S; Willi, Barbara; Riond, Barbara; Hoelzle, K; Hoelzle, L E; Wittenbrink, M M; Tasker, S; Wengi, N; Reusch, Claudia E; Lutz, H; Hofmann-Lehmann, R;The natural transmission routes of the three feline haemotropic mycoplasmas - Mycoplasma haemofelis ,' Candidatus Mycoplasma haemominutum', and 'Candidatus Mycoplasma turicensis' (CMt) - are largely unknown. Since CMt has been detected in the saliva of infected cats using PCR, we hypothesised that direct transmission via social or aggressive contact may occur. The aim of this study was to evaluate this transmission route. CMt-positive saliva and blood samples were obtained from three prednisolone- treated specific pathogen-free (SPF) cats that were infected intraperitoneally with CMt. Five SPF cats were inoculated with CMt-positive saliva or blood subcutaneously to mimic cat bites, and five cats were inoculated orally with blood or oronasally with saliva to mimic social contact. Blood samples were monitored for CMt infection using quantitative real-time PCR and for seroconversion using a novel western blot assay. Neither oronasal nor subcutaneous inoculation with CMt-positive saliva led to CMt infection in the recipient cats, as determined by PCR, independent of prior prednisolone treatment. However, when blood containing the same CMt dose was given subcutaneously, 4 of the 5 cats became PCR-positive, while none of the 5 cats inoculated orally with up to 500 lL of CMt-positive blood became PCR-positive. Subsequently, the latter cats were successfully subcutaneously infected with blood. All 13 CMt-exposed cats seroconverted. In conclusion, CMt transmission by social contact seems less likely than transmission by aggressive interaction. The latter transmission may occur if the recipient cat is exposed to blood from an infected cat. haemotropic mycoplasma / transmission / 'Candidatus Mycoplasma turicensis' / real-time TaqMan PCR / seroconversion
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2009Full-Text: http://europepmc.org/articles/PMC2701178Data sources: PubMed CentralZurich Open Repository and ArchiveOther literature type . 2009Mémoires en Sciences de l'Information et de la CommunicationArticle . 2009Full-Text: https://hal.science/hal-00903107/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/vetres/2009028&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 84 citations 84 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2009Full-Text: http://europepmc.org/articles/PMC2701178Data sources: PubMed CentralZurich Open Repository and ArchiveOther literature type . 2009Mémoires en Sciences de l'Information et de la CommunicationArticle . 2009Full-Text: https://hal.science/hal-00903107/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1051/vetres/2009028&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2020Embargo end date: 01 Jan 2020 Spain, France, Finland, Spain, Portugal, Switzerland, Ireland, CyprusPublisher:Public Library of Science (PLoS) Publicly fundedFunded by:SNSF | Promoting Mental Health a..., SNSF | Effects of Psychological ...SNSF| Promoting Mental Health and Prosocial Behaviors: Harnessing New Technologies for Therapy and Training in Real-Life Environments ,SNSF| Effects of Psychological Flexibility in Social Context: A Multi-Level ApproachGloster, A.T.; Lamnisos, D.; Lubenko, J.; Presti, G.; Squatrito, V.; Constantinou, M.; Nicolaou, C.; Papacostas, S.; Aydin, G.; Chong, Y.Y.; Chien, W.T.; Cheng, H.Y.; Ruiz, F.J.; Garcia-Martin, M.B.; Obando-Posada, D.P.; Segura-Vargas, M.A.; Vasiliou, V.S.; McHugh, L.; Höfer, S.; Baban, A.; Neto, D.D.; da Silva, A.N.; Monestès, J.L.; Alvarez-Galvez, J.; Paez-Blarrina, M.; Montesinos, F.; Valdivia-Salas, S.; Ori, D.; Kleszcz, B.; Lappalainen, R.; Ivanovic, I.; Gosar, D.; Dionne, F.; Merwin, R.M.; Kassianos, A.P.; Karekla, M.;Background The COVID-19 pandemic triggered vast governmental lockdowns. The impact of these lockdowns on mental health is inadequately understood. On the one hand such drastic changes in daily routines could be detrimental to mental health. On the other hand, it might not be experienced negatively, especially because the entire population was affected. Methods The aim of this study was to determine mental health outcomes during pandemic induced lockdowns and to examine known predictors of mental health outcomes. We therefore surveyed n = 9, 565 people from 78 countries and 18 languages. Outcomes assessed were stress, depression, affect, and wellbeing. Predictors included country, sociodemographic factors, lockdown characteristics, social factors, and psychological factors. Results Results indicated that on average about 10% of the sample was languishing from low levels of mental health and about 50% had only moderate mental health. Importantly, three consistent predictors of mental health emerged: social support, education level, and psychologically flexible (vs. rigid) responding. Poorer outcomes were most strongly predicted by a worsening of finances and not having access to basic supplies. Conclusions These results suggest that on whole, respondents were moderately mentally healthy at the time of a population-wide lockdown. The highest level of mental health difficulties were found in approximately 10% of the population. Findings suggest that public health initiatives should target people without social support and those whose finances worsen as a result of the lockdown. Interventions that promote psychological flexibility may mitigate the impact of the pandemic.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7774914Data sources: PubMed CentralRepositorio de Objetos de Docencia e Investigación de la Universidad de CádizArticle . 2020License: CC BYJyväskylä University Digital ArchiveArticle . 2020 . Peer-reviewedLicense: CC BYData sources: Jyväskylä University Digital ArchiveCork Open Research Archive (CORA)Article . 2020License: CC BYData sources: Cork Open Research Archive (CORA)Recolector de Ciencia Abierta, RECOLECTA; Digital Repository of University of ZaragozaArticle . 2020License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 131 citations 131 popularity Top 1% influence Top 10% impulse Top 0.1% Powered by BIP!visibility 119visibility views 119 download downloads 112 Powered bymore_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2020Full-Text: http://europepmc.org/articles/PMC7774914Data sources: PubMed CentralRepositorio de Objetos de Docencia e Investigación de la Universidad de CádizArticle . 2020License: CC BYJyväskylä University Digital ArchiveArticle . 2020 . Peer-reviewedLicense: CC BYData sources: Jyväskylä University Digital ArchiveCork Open Research Archive (CORA)Article . 2020License: CC BYData sources: Cork Open Research Archive (CORA)Recolector de Ciencia Abierta, RECOLECTA; Digital Repository of University of ZaragozaArticle . 2020License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5451/unibas-ep81681&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2010 United Kingdom, FrancePublisher:Elsevier BV Funded by:SNSF | The role of innate recept..., WTSNSF| The role of innate receptors in dendritic cell and B lymphocyte activation ,WTAuthors: Beltramello, Martina; Williams, Katherine L.; Simmons, Cameron P.; Macagno, Annalisa; +13 AuthorsBeltramello, Martina; Williams, Katherine L.; Simmons, Cameron P.; Macagno, Annalisa; Simonelli, Luca; Quyen, Nguyen Than Ha; Sukupolvi-Petty, Soila; Navarro-Sanchez, Erika; Young, Paul R.; de Silva, Aravinda M.; Rey, Félix A.; Varani, Luca; Whitehead, Stephen S; Diamond, Michael S.; Harris, Eva; Lanzavecchia, Antonio; Sallusto, Federica;International audience; Antibodies protect against homologous Dengue virus (DENV) infection but can precipitate severe dengue by promoting heterotypic virus entry via Fcγ receptors (FcγR). We immortalized memory B cells from individuals after primary or secondary infection and analyzed anti-DENV monoclonal antibodies (mAbs) thus generated. MAbs to envelope (E) protein domain III (DIII) were either serotype specific or cross-reactive and potently neutralized DENV infection. DI/DII- or viral membrane protein prM-reactive mAbs neutralized poorly and showed broad cross-reactivity with the four DENV serotypes. All mAbs enhanced infection at subneutralizing concentrations. Three mAbs targeting distinct epitopes on the four DENV serotypes and engineered to prevent FcγR binding did not enhance infection and neutralized DENV in vitro and in vivo as postexposure therapy in a mouse model of lethal DENV infection. Our findings reveal an unexpected degree of cross-reactivity in human antibodies against DENV and illustrate the potential for an antibody-based therapy to control severe dengue.
Cell Host & Microbe arrow_drop_down Oxford University Research Archive; Cell Host & MicrobeOther literature type . Article . 2016 . 2010 . Peer-reviewedLicense: Elsevier Non-Commercialadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.chom.2010.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 509 citations 509 popularity Top 1% influence Top 1% impulse Top 1% Powered by BIP!more_vert Cell Host & Microbe arrow_drop_down Oxford University Research Archive; Cell Host & MicrobeOther literature type . Article . 2016 . 2010 . Peer-reviewedLicense: Elsevier Non-Commercialadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.chom.2010.08.007&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2019 France, SwitzerlandPublisher:MDPI AG Funded by:EC | GASTRICGLYCOEXPLORER, NIH | UniProt: A centralized pr..., SNSF | A context based knowledge...EC| GASTRICGLYCOEXPLORER ,NIH| UniProt: A centralized protein sequence and function resource ,SNSF| A context based knowledge resource integrating HIV and Mtb molecular biology with host-pathogen and drug-resistance dataAuthors: Philippe Le Mercier; Julien Mariethoz; Josefina Lascano-Maillard; François Bonnardel; +3 AuthorsPhilippe Le Mercier; Julien Mariethoz; Josefina Lascano-Maillard; François Bonnardel; Anne Imberty; Sylvie Ricard-Blum; Frédérique Lisacek;International audience; Evidence of the mediation of glycan molecules in the interaction between viruses and their hosts is accumulating and is now partially reflected in several online databases. Bioinformatics provides convenient and efficient means of searching, visualizing, comparing, and sometimes predicting, interactions in numerous and diverse molecular biology applications related to the-omics fields. As viromics is gaining momentum, bioinformatics support is increasingly needed. We propose a survey of the current resources for searching, visualizing, comparing, and possibly predicting host-virus interactions that integrate the presence and role of glycans. To the best of our knowledge, we have mapped the specialized and general-purpose databases with the appropriate focus. With an illustration of their potential usage, we also discuss the strong and weak points of the current bioinformatics landscape in the context of understanding viral infection and the immune response to it.
Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6521074Data sources: PubMed CentralMémoires en Sciences de l'Information et de la CommunicationArticle . 2019License: CC BYFull-Text: https://hal.science/hal-02109612/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/v11040374&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 5 citations 5 popularity Average influence Average impulse Average Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Europe PubMed CentralArticle . 2019Full-Text: http://europepmc.org/articles/PMC6521074Data sources: PubMed CentralMémoires en Sciences de l'Information et de la CommunicationArticle . 2019License: CC BYFull-Text: https://hal.science/hal-02109612/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.3390/v11040374&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article 2014 FrancePublisher:Cold Spring Harbor Laboratory Funded by:SNSF | Regulation of early to la..., EC | MODELISTSNSF| Regulation of early to late endosomal traffic ,EC| MODELISTAuthors: Cossart, Pascale; Helenius, Ari;Cossart, Pascale; Helenius, Ari;International audience; Of the many pathogens that infect humans and animals, a large number use cells of the host organism as protected sites for replication. To reach the relevant intracellular compartments, they take advantage of the endocytosis machinery and exploit the network of endocytic organelles for penetration into the cytosol or as sites of replication. In this review, we discuss the endocytic entry processes used by viruses and bacteria and compare the strategies used by these dissimilar classes of pathogens.
Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/cshperspect.a016972&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 302 citations 302 popularity Top 1% influence Top 10% impulse Top 1% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1101/cshperspect.a016972&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Netherlands, Switzerland, Norway, SwitzerlandPublisher:Springer Science and Business Media LLC Funded by:SNSF | What is Sustainable Inten...SNSF| What is Sustainable Intensification? Operationalizing Sustainable Agricultural Intensification Pathways in Europe (SIPATH)Helfenstein, Julian; Bürgi, Matthias; Debonne, Niels; Dimopoulos, Thymios; Diogo, Vasco; Dramstad, Wenche; Edlinger, Anna; Garcia-Martin, Maria; Hernik, Józef; Kizos, Thanasis; Lausch, Angela; Levers, Christian; Mohr, Franziska; Moreno, Gerardo; Pazur, Robert; Siegrist, Michael; Swart, Rebecca; Thenail, Claudine; Verburg, Peter H.; Williams, Tim G.; Zarina, Anita; Herzog, Felix;pmid: 36017120
pmc: PMC9397162
It has been shown that the COVID-19 pandemic affected some agricultural systems more than others, and even within geographic regions, not all farms were affected to the same extent. To build resilience of agricultural systems to future shocks, it is key to understand which farms were affected and why. In this study, we examined farmers' perceived robustness to COVID-19, a key resilience capacity. We conducted standardized farmer interviews (n = 257) in 15 case study areas across Europe, covering a large range of socio-ecological contexts and farm types. Interviews targeted perceived livelihood impacts of the COVID-19 pandemic on productivity, sales, price, labor availability, and supply chains in 2020, as well as farm(er) characteristics and farm management. Our study corroborates earlier evidence that most farms were not or only slightly affected by the first wave(s) of the pandemic in 2020, and that impacts varied widely by study region. However, a significant minority of farmers across Europe reported that the pandemic was "the worst crisis in a lifetime" (3%) or "the worst crisis in a decade" (7%). Statistical analysis showed that more specialized and intensive farms were more likely to have perceived negative impacts. From a societal perspective, this suggests that highly specialized, intensive farms face higher vulnerability to shocks that affect regional to global supply chains. Supporting farmers in the diversification of their production systems while decreasing dependence on service suppliers and supply chain actors may increase their robustness to future disruptions. Agronomy for Sustainable Development, 42 (5) ISSN:1773-0155 ISSN:1774-0746
NARCIS; Research@WUR arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022Full-Text: https://hal.science/hal-04189033/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s13593-022-00820-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen hybrid 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert NARCIS; Research@WUR arrow_drop_down Bern Open Repository and Information System (BORIS)Article . 2022 . Peer-reviewedData sources: Bern Open Repository and Information System (BORIS)Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022Full-Text: https://hal.science/hal-04189033/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1007/s13593-022-00820-5&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2015 Switzerland, FrancePublisher:American Society for Microbiology Funded by:SNSF | Rhinovirus et entérovirus...SNSF| Rhinovirus et entérovirus: déterminants génomiques et phénotypes associésJulien, Lupo; Isabelle, Schuffenecker; Christine, Morel-Baccard; Julie, Bardet; Valérie, Payen; Laurent, Kaiser; Samuel, Constant; Johannes Alexander, Lobrinus; Nathalie, Lin-Marq; Bruno, Lina; Patrice, Morand; Caroline, Tapparel;ABSTRACT We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.
Europe PubMed Centra... arrow_drop_down Journal of Clinical MicrobiologyArticle . 2015 . Peer-reviewedLicense: ASM Journals Non-Commercial TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1128/jcm.03484-14&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen bronze 13 citations 13 popularity Average influence Average impulse Top 10% Powered by BIP!more_vert Europe PubMed Centra... arrow_drop_down Journal of Clinical MicrobiologyArticle . 2015 . Peer-reviewedLicense: ASM Journals Non-Commercial TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1128/jcm.03484-14&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eu