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description Publicationkeyboard_double_arrow_right Article 2023 France, Belgium, Italy, Spain, Sweden, United Kingdom, Sweden, PolandPublisher:Elsevier BV Funded by:EC | ALECEC| ALECTianyu Zhao; Iana Markevych; Elaine Fuertes; Kees de Hoogh; Simone Accordini; Anne Boudier; Lidia Casas; Bertil Forsberg; Judith Garcia Aymerich; Marco Gnesi; Mathias Holm; Christer Janson; Deborah Jarvis; Ane Johannessen; Rudolf A. Jörres; Stefan Karrasch; Benedicte Leynaert; José Antonio Maldonado Perez; Andrei Malinovschi; Jesús Martínez-Moratalla; Lars Modig; Dennis Nowak; James Potts; Nicole Probst-Hensch; José Luis Sánchez-Ramos; Valerie Siroux; Isabel Urrutia Landa; Danielle Vienneau; Simona Villani; Bénédicte Jacquemin; Joachim Heinrich;Background: While the adverse effects of short-term ambient ozone exposure on lung function are well-documented, the impact of long-term exposure remains poorly understood, especially in adults. Methods: We aimed to investigate the association between long-term ozone exposure and lung function decline. The 3014 participants were drawn from 17 centers across eight countries, all of which were from the European Community Respiratory Health Survey (ECRHS). Spirometry was conducted to measure pre-bronchodilation forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) at approximately 35, 44, and 55 years of age. We assigned annual mean values of daily maximum running 8-h average ozone concentrations to individual residential addresses. Adjustments were made for PM2.5, NO2, and greenness. To capture the ozone-related change in spirometric parameters, our linear mixed effects regression models included an interaction term between long-term ozone exposure and age. Findings: Mean ambient ozone concentrations were approximately 65 μg/m³. A one interquartile range increase of 7 μg/m³ in ozone was associated with a faster decline in FEV1 of -2.08 mL/year (95% confidence interval: -2.79, -1.36) and in FVC of -2.86 mL/year (-3.73, -1.99) mL/year over the study period. Associations were robust after adjusting for PM2.5, NO2, and greenness. The associations were more pronounced in residents of northern Europe and individuals who were older at baseline. No consistent associations were detected with the FEV1/FVC ratio. Interpretation: Long-term exposure to elevated ambient ozone concentrations was associated with a faster decline of spirometric lung function among middle-aged European adults over a 20-year period. Funding: German Research Foundation. The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study (www.alecstudy.org), which has also received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health are reported in the Supplementary Material.
IRIS - Università de... arrow_drop_down IRIS - Università degli Studi di Verona; The Lancet Regional Health. EuropeArticle . 2023 . Peer-reviewedLicense: CC BYIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaSpiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryThe Lancet Regional Health. EuropeArticle . 2023Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.lanepe.2023.100729&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert IRIS - Università de... arrow_drop_down IRIS - Università degli Studi di Verona; The Lancet Regional Health. EuropeArticle . 2023 . Peer-reviewedLicense: CC BYIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaSpiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryThe Lancet Regional Health. EuropeArticle . 2023Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.lanepe.2023.100729&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 France, Sweden, Poland, Italy, Sweden, Italy, Belgium, Spain, Norway, United Kingdom, SwitzerlandPublisher:Elsevier BV Funded by:EC | ALECEC| ALECIana Markevych; Tianyu Zhao; Elaine Fuertes; Alessandro Marcon; Payam Dadvand; Danielle Vienneau; Judith Garcia Aymerich; Dennis Nowak; Kees de Hoogh; Deborah Jarvis; Michael J. Abramson; Simone Accordini; Andre FS Amaral; Hayat Bentouhami; Randi Jacobsen Bertelsen; Anne Boudier; Roberto Bono; Gayan Bowatte; Lidia Casas; Shyamali C Dharmage; Bertil Forsberg; Thorarinn Gislason; Marco Gnesi; Mathias Holm; Benedicte Jacquemin; Christer Janson; Rain Jogi; Ane Johannessen; Dirk Keidel; Benedicte Leynaert; José Antonio Maldonado Perez; Pierpaolo Marchetti; Enrica Migliore; Jesús Martínez-Moratalla; Hans Orru; Isabelle Pin; James Potts; Nicole Probst-Hensch; Andrea Ranzi; José Luis Sánchez-Ramos; Valerie Siroux; David Soussan; Jordi Sunyer; Isabel Urrutia Landa; Simona Villani; Joachim Heinrich;handle: 2318/1913411 , 10067/1971420151162165141 , 11562/1097567 , 11250/3115606
pmid: 37336027
Background: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is affected. Objective: We explored the association between residential greenspace and change in lung function over 20 years in 5559 adults from 22 centers in 11 countries participating in the population-based, international European Community Respiratory Health Survey. Methods: Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were measured by spirometry when participants were approximately 35 (1990-1994), 44 (1999-2003), and 55 (2010-2014) years old. Greenness was assessed as the mean Normalized Difference Vegetation Index (NDVI) in 500 m, 300 m, and 100 m circular buffers around the residential addresses at the time of lung function measurement. Green spaces were defined as the presence of agricultural, natural, or urban green spaces in a circular 300 m buffer. Associations of these greenspace parameters with the rate of lung function change were assessed using adjusted linear mixed effects regression models with random intercepts for subjects nested within centers. Sensitivity analyses considered air pollution exposures. Results: A 0.2-increase (average interquartile range) in NDVI in the 500 m buffer was consistently associated with a faster decline in FVC (-1.25 mL/year [95% confidence interval: -2.18 to -0.33]). These associations were especially pronounced in females and those living in areas with low PM10 levels. We found no consistent associations with FEV1 and the FEV1/FVC ratio. Residing near forests or urban green spaces was associated with a faster decline in FEV1, while agricultural land and forests were related to a greater decline in FVC. Conclusions: More residential greenspace was not associated with better lung function in middle-aged European adults. Instead, we observed slight but consistent declines in lung function parameters. The potentially detrimental association requires verification in future studies. The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study (https://www.alecstudy.org), which has also received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health are reported in the Supplementary Material. ISGlobal is a member of CERCA Programme/Generalitat de Catalunya. These sources of funding had no role in the study design, the collection, analysis and interpretation of data, the writing of the report, and in the decision to submit the article for publication.
Archivio Istituziona... arrow_drop_down Spiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryEnvironment InternationalArticle . 2023Data sources: Institutional Repository Universiteit AntwerpenIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaBergen Open Research Archive - UiB; Norwegian Open Research ArchivesArticle . 2023 . Peer-reviewedLicense: CC BYHAL-Rennes 1; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2023License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!visibility 1visibility views 1 download downloads 3 Powered bymore_vert Archivio Istituziona... arrow_drop_down Spiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryEnvironment InternationalArticle . 2023Data sources: Institutional Repository Universiteit AntwerpenIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaBergen Open Research Archive - UiB; Norwegian Open Research ArchivesArticle . 2023 . Peer-reviewedLicense: CC BYHAL-Rennes 1; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2023License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 France, Italy, PolandPublisher:Elsevier BV Funded by:EC | ALEC, NIH | COMMUNITY BASED STUDY ON ...EC| ALEC ,NIH| COMMUNITY BASED STUDY ON OCCUPATIONAL ASTHMA, ECRHS-OAAnne, Boudier; Iana, Markevych; Bénédicte, Jacquemin; Michael J, Abramson; Simone, Accordini; Bertil, Forsberg; Elaine, Fuertes; Judith, Garcia-Aymerich; Joachim, Heinrich; Ane, Johannessen; Bénédicte, Leynaert; Isabelle, Pin; Valérie, Siroux;International audience; BACKGROUND: Associations of long-term exposure to air pollution and greenspace with health-related quality of life (HRQOL) are poorly studied and few studies have accounted for asthma-rhinitis status. OBJECTIVE: To assess the associations of air pollution and greenspace with HRQOL and whether asthma and/or rhinitis modify these associations. METHODS: The study was based on the participants in the second (2000-2002, n = 6542) and third (2011-2013, n = 3686) waves of the European Community Respiratory Health Survey (ECRHS) including 19 centres. The mean follow-up time was 11.3 years. HRQOL was assessed by the SF-36 Physical and Mental Component Summary scores (PCS and MCS). NO(2), PM(2.5) and PM(10) annual concentrations were estimated at the residential address from existing land-use regression models. Greenspace around the residential address was estimated by the (i) mean of the Normalized Difference Vegetation Index (NDVI) and by the (ii) presence of green spaces within a 300 m buffer. Associations of each exposure variable with PCS and MCS were assessed by mixed linear regression models, accounting for the multicentre design and repeated data, and adjusting for potential confounders. Analyses were stratified by asthma-rhinitis status. RESULTS: The mean (SD) age of the ECRHS-II and III participants was 43 (7.1) and 54 (7.2) years, respectively, and 48 % were men. Higher NO(2), PM(2.5) and PM(10) concentrations were associated with lower MCS (regression coefficients [95%CI] for one unit increase in the inter-quartile range of exposures were -0.69 [-1.23; -0.15], -1.79 [-2.88; -0.70], -1.80 [-2.98; -0.62] respectively). Higher NDVI and presence of forests were associated with higher MCS. No consistent associations were observed for PCS. Similar association patterns were observed regardless of asthma-rhinitis status. CONCLUSION: European adults who resided at places with higher air pollution and lower greenspace were more likely to have lower mental component of HRQOL. Asthma or rhinitis status did not modify these associations.
Jagiellonian Univers... arrow_drop_down IRIS - Università degli Studi di VeronaArticle . 2022Data sources: IRIS - Università degli Studi di VeronaThe Science of The Total Environment; IRIS - Università degli Studi di VeronaArticle . 2022 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu6 citations 6 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Jagiellonian Univers... arrow_drop_down IRIS - Università degli Studi di VeronaArticle . 2022Data sources: IRIS - Università degli Studi di VeronaThe Science of The Total Environment; IRIS - Università degli Studi di VeronaArticle . 2022 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.scitotenv.2022.157693&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Australia, France, Spain, NorwayPublisher:Elsevier BV Funded by:WT | The Born in Bradford (BiB..., EC | ENRIECO, EC | ATHLETE +5 projectsWT| The Born in Bradford (BiB) Study an international biomedical resource for exploring genetic and early life determinants of health and development in a deprived multi-ethnic population. ,EC| ENRIECO ,EC| ATHLETE ,EC| ESCAPE ,EC| HELIX ,EC| CHICOS ,EC| ENVIROGENOMARKERS ,EC| LIFECYCLEde Prado-Bert, Paula; Warembourg, Charline; Dedele, Audrius; Heude, Barbara; Borràs, Eva; Sabidó, Eduard; Aasvang, Gunn Marit; Lepeule, Johanna; Wright, John; Urquiza, Jose; Gützkow, Kristine B.; Maitre, Léa; Chatzi, Leda; Casas, Maribel; Vafeiadi, Marina; Nieuwenhuijsen, Mark J.; de Castro, Montserrat; Grazuleviciene, Regina; McEachan, Rosemary R.C.; Basagaña, Xavier; Vrijheid, Martine; Sunyer, Jordi; Bustamante, Mariona;pmid: 35292243
Exposure to air pollution influences children's health, however, the biological mechanisms underlying these effects are not completely elucidated. We investigated the association between short- and medium-term outdoor air pollution exposure with protein profiles and their link with blood pressure in 1170 HELIX children aged 6-11 years. Different air pollutants (NO2, PM10, PM2.5, and PM2.5abs) were estimated based on residential and school addresses at three different windows of exposure (1-day, 1-week, and 1-year before clinical and molecular assessment). Thirty-six proteins, including adipokines, cytokines, or apolipoproteins, were measured in children's plasma using Luminex. Systolic and diastolic blood pressure (SBP and DBP) were measured following a standardized protocol. We performed an association study for each air pollutant at each location and time window and each outcome, adjusting for potential confounders. After correcting for multiple-testing, hepatocyte growth factor (HGF) and interleukin 8 (IL8) levels were positively associated with 1-week home exposure to some of the pollutants (NO2, PM10, or PM2.5). NO2 1-week home exposure was also related to higher SBP. The mediation study suggested that HGF could explain 19% of the short-term effect of NO2 on blood pressure, but other study designs are needed to prove the causal directionality between HGF and blood pressure. The study received funding from the European Community’s Seventh Framework Programme (FP7/2007–206) (grant agreement no 308333) (HELIX project), the H2020-EU.3.1.2. - Preventing Disease Programme (grant agreement no 874583) (ATHLETE project) and from the European Union’s Horizon 2020 research and innovation programme (grant Agreement number: 733206) (Early Life stressors and Lifecycle Health (LIFECYCLE)). BiB received funding from the Welcome Trust (WT101597MA), from the UK Medical Research Council (MRC) and Economic and Social Science Research Council (ESRC) (MR/N024397/ 1). The study was supported by the European Union FP7 programmes (FP7/ 2007–2013, HELIX, ESCAPE, ENRIECO, Medall projects). INMA was supported by grants from the Instituto de Salud Carlos III, CIBERESP, and the Generalitat de Catalunya-CIRIT. KANC was funded by the grant of the Lithuanian Agency for Science Innovation and Technology (6-04-2014_31V-66). The Rhea project was financially supported by European projects (EU FP6-2003-Food-3-NewGeneris, EU FP6. STREP Hiwate, EU FP7 ENV. 2007.1.2.2.2. Project No 211250 Escape, EU FP7- 2008-ENV-1.2.1.4 Envirogenomarkers, EU FP7-HEALTH-2009- single stage CHICOS, EU FP7 ENV. 2008.1.2.1.6. Proposal No 226285 ENRIECO, EU- FP7- HEALTH-2012 Proposal No 308333 HELIX). MC received funding from Instituto Carlos III (Ministry of Economy and Competitiveness) (CD12/00563 and MS16/00128). JU is supported by Spanish regional program PERIS (Ref.: SLT017/20/ 000119) Granted by Departament de Salut de la Generalitat de Catalunya. The CRG/UPF Proteomics Unit is part of the Spanish Infrastructure for Omics Technologies (ICTS OmicsTech) and it is member of the ProteoRed PRB3 consortium which is supported by grant PT17/0019 of the PE I + D + i 2013–2016 from the Instituto de Salud Carlos III (ISCIII)
ACU Research Bank arrow_drop_down Norwegian Institute of Public Health Open RepositoryArticle . 2022Data sources: Norwegian Institute of Public Health Open Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routeshybrid 5 citations 5 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert ACU Research Bank arrow_drop_down Norwegian Institute of Public Health Open RepositoryArticle . 2022Data sources: Norwegian Institute of Public Health Open Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1016/j.envres.2022.113109&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2022 France, France, France, France, GermanyPublisher:Copernicus GmbH Funded by:EC | IMMERSE, NSF | EarthCube Data Capabiliti..., NSF | NSFGEO-NERC: Collaborativ... +3 projectsEC| IMMERSE ,NSF| EarthCube Data Capabilities: A Cloud-Native Data Repository for the Geoscience Community ,NSF| NSFGEO-NERC: Collaborative Research: Assessing the influence of sub-annual variability in the AMOC on the Gulf Stream and the atmosphere ,ANR| CONTACTS ,ANR| DEEPER ,EC| ESiWACE2T. Uchida; J. Le Sommer; C. Stern; R. P. Abernathey; C. Holdgraf; A. Albert; L. Brodeau; L. Brodeau; E. P. Chassignet; X. Xu; J. Gula; J. Gula; G. Roullet; N. Koldunov; S. Danilov; Q. Wang; D. Menemenlis; C. Bricaud; B. K. Arbic; J. F. Shriver; F. Qiao; B. Xiao; A. Biastoch; A. Biastoch; R. Schubert; R. Schubert; B. Fox-Kemper; W. K. Dewar; W. K. Dewar; A. Wallcraft;Abstract. With the increase in computational power, ocean models with kilometer-scale resolution have emerged over the last decade. These models have been used for quantifying the energetic exchanges between spatial scales, informing the design of eddy parametrizations, and preparing observing networks. The increase in resolution, however, has drastically increased the size of model outputs, making it difficult to transfer and analyze the data. It remains, nonetheless, of primary importance to assess more systematically the realism of these models. Here, we showcase a cloud-based analysis framework proposed by the Pangeo project that aims to tackle such distribution and analysis challenges. We analyze the output of eight submesoscale-permitting simulations, all on the cloud, for a crossover region of the upcoming Surface Water and Ocean Topography (SWOT) altimeter mission near the Gulf Stream separation. The cloud-based analysis framework (i) minimizes the cost of duplicating and storing ghost copies of data and (ii) allows for seamless sharing of analysis results amongst collaborators. We describe the framework and provide example analyses (e.g., sea-surface height variability, submesoscale vertical buoyancy fluxes, and comparison to predictions from the mixed-layer instability parametrization). Basin- to global-scale, submesoscale-permitting models are still at their early stage of development; their cost and carbon footprints are also rather large. It would, therefore, benefit the community to document the different model configurations for future best practices. We also argue that an emphasis on data analysis strategies would be crucial for improving the models themselves.
OceanRep; Geoscienti... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus PublicationsElectronic Publication Information CenterArticle . 2022Data sources: Electronic Publication Information CenterArchiMer - Institutional Archive of IfremerOther literature type . 2022Data sources: ArchiMer - Institutional Archive of IfremerINRIA a CCSD electronic archive server; Mémoires en Sciences de l'Information et de la Communication; HAL-IRDArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/gmd-15-5829-2022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert OceanRep; Geoscienti... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus PublicationsElectronic Publication Information CenterArticle . 2022Data sources: Electronic Publication Information CenterArchiMer - Institutional Archive of IfremerOther literature type . 2022Data sources: ArchiMer - Institutional Archive of IfremerINRIA a CCSD electronic archive server; Mémoires en Sciences de l'Information et de la Communication; HAL-IRDArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/gmd-15-5829-2022&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Italy, FrancePublisher:American Institute of Aeronautics and Astronautics (AIAA) Funded by:EC | ICE GENESIS, EC | UTOPIAEEC| ICE GENESIS ,EC| UTOPIAEGiulio Gori; Pietro Marco Congedo; Olivier Le Maitre; Tommaso Bellosta; Alberto Guardone;doi: 10.2514/1.c036545
handle: 11311/1191613
International audience; In-flight ice accretion under parametric uncertainty is investigated. Three test cases are presented which reproduce experiments carried out at the NASA's Glenn Icing Research Tunnel (IRT) facility. A preliminary accuracy assessment, achieved comparing numerical predictions against experimental observations, confirm the robustness and the predictiveness of the computerized icing model. Besides, sensitivity analyses highlight the variance of the targeted outputs with respect to the different uncertain inputs. In rime icing conditions, a predominant role is played by the uncertainty affecting the airfoil angle of attack, the cloud liquid water content and the droplets’ mean volume diameter. In glaze icing condition, the sensitivity analysis shows instead that the output variability is due mainly to the ambient temperature uncertainty. Results expose a major criticality of standard uncertainty quantification techniques. The issue is inherent the approximation of the full icing model behavior in domain regions scarcely affected by ice build up. To mitigate the issue, a non-linear regression method is proposed and applied.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.2514/1.c036545&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routesbronze 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Spain, Spain, Spain, Netherlands, France, France, Australia, FrancePublisher:Elsevier BV Funded by:WT | The Born in Bradford (BiB..., NIH | Effects of DDE exposure o..., NIH | Pilot Project Program +6 projectsWT| The Born in Bradford (BiB) Study an international biomedical resource for exploring genetic and early life determinants of health and development in a deprived multi-ethnic population. ,NIH| Effects of DDE exposure on adipose tissue function, weight loss and metabolic improvement after bariatric surgery: A new paradigm for study of lipophilic chemicals ,NIH| Pilot Project Program ,NIH| Hepatotoxic effects of perfluoroalkyl substances: a new epidemiological approach for studying environmental fatty liver disease ,EC| EUCAN-Connect ,NIH| Environmental Chemical Exposures and Longitudinal Changes of Glucose Metabolism, Insulin Sensitivity and B Cell Function in Youth ,NHMRC| An evaluation of bone density screening in premenopausal women ,EC| DENAMIC ,EC| HELIXAuthors: Binter, Anne-Claire; Bernard, Jonathan Y.; Mon-Williams, Mark; Andiarena, Ainara; +15 AuthorsBinter, Anne-Claire; Bernard, Jonathan Y.; Mon-Williams, Mark; Andiarena, Ainara; González-Safont, Llúcia; Vafeiadi, Marina; Lepeule, Johanna; Soler-Blasco, Raquel; Alonso, Lucia; Kampouri, Mariza; Mceachan, Rosie; Santa-Marina, Loreto; Wright, John; Chatzi, Leda; Sunyer, Jordi; Philippat, Claire; Nieuwenhuijsen, Mark; Vrijheid, Martine; Guxens, Mònica;Acknowledgements We are grateful to all the participating children, parents, practi-tioners and researchers in the four countries who took part in this study. This work was supported by funding from the European Community's Seventh Framework Programme [FP7/2007-206 n 308333; the HELIX project] . This INMA cohort was funded by grants from Instituto de Salud Carlos III (Red INMA G03/176; CB06/02/0041; PI041436; PI081151 incl. FEDER funds, FIS PI06/0867, FIS-PI09/00090, FIS and FIS-PI18/01142 incl. FEDER funds, FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, PI16/00118 and PI17/00663; FIS-FSE: 17/00260; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, and CPII18/00018) , from UE (FP7-ENV-2011 cod 282957, HEALTH.2010.2.4.5-1, and H2020 n 824989) , Generalitat de Catalunya-CIRIT 1999SGR 00241, Fundacio La marato de TV3 (090430) , Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249) , Alicia Koplowitz Foundation 2017, CIBERESP, Department of Health of the Basque Government (2013111089, 2009111069, 2013111089, 2015111065 and 2018111086) , Provincial Government of Gipuzkoa (DFG06/002, DFG08/001, DFG15/221 and DFG 89/17) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain) . We acknowledge support from the Spanish Ministry of Science and Inno-vation and the State Research Agency through the "Centro de Excelencia Severo Ochoa 2019-2023" Program (CEX2018-000806-S) , and support from the Generalitat de Catalunya through the CERCA Program. The work was also supported by MICINN [MTM2015-68140-R] and Centro Nacional de Genotipado-CEGEN-PRB2-ISCIII (Spain) . The Rhea project was financially supported by European projects, and the Greek Ministry of Health (Program of Prevention of obesity and neurodevelopmental disorders in preschool children, in Heraklion district, Crete, Greece: 2011-2014; "Rhea Plus": Primary Prevention Program of Environmental Risk Factors for Reproductive Health, and Child Health: 2012-15) . This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Collaboration for Applied Health Research and Care (CLAHRC) for Yorkshire and Humber (UK) . The EDEN study was supported by Foundation for medical research (FRM) , National Agency for Research (ANR) , National Institute for Research inPublic health (IRESP: TGIR cohorte sante 2008 program) , French Min-istry of Health (DGS) , French Ministry of Research, INSERM Bone and Joint Diseases National Research (PRO-A) , and Human Nutrition Na-tional Research Programs, Paris-Sud University, Nestle, French National Institute for Population Health Surveillance (InVS) , French National Institute for Health Education (INPES) , the European Union FP7 pro-grams (ESCAPE, ENRIECO, Medall projects) , Diabetes National Research Program (through a collaboration with the French Association of Diabetic Patients (AFD) ) , French Agency for Environmental Health Safety and French National Agency for Food Security (now ANSES) , Mutuelle Generale de l'Education Nationale a complementary health insurance (MGEN) , French-speaking association for the study of diabetes and metabolism (ALFEDIAM) . Core support for Born in Bradford is also provided by the Wellcome Trust (WT101597MA, UK) . Born in Bradford (BiB) is only possible because of the enthusiasm and commitment of the children and parents in BiB. We are grateful to all the participants, health professionals, schools and researchers who have made BiB happen. BiB receives funding from the ESRC/MRC, the Wellcome Trust (WT101597MA) and the National Institute for Health Research York-shire and Humber ARC (reference: NIHR20016) . M. Mon-Williams was supported by a Fellowship from the Alan Turing Institute. Additional funding from the National Institute of Environmental Health Science supported Dr Chatzi (R01ES030691, R01ES029944, R01ES030364, R21ES029681, and P30ES007048) . The views expressed are those of the authors, and not necessarily those of the NHS or the NIHR. None of the funders were involved in designing the study, collecting the data, analyzing or interpreting the data, deciding to submit the article for publication, or the writing of the report. Data sharing statement The HELIX data warehouse has been established as an accessible resource for collaborative research involving researchers external to the project. Access to HELIX data is based on approval by the HELIX Project Executive Committee and by the individual cohorts. Further details on the content of the data warehouse (data catalogue) and procedures for external access are described on the project website (http:// www.proj-ecthelix.eu/index.php/es/data-inventory) . [EN]Background: The urban environment may influence neurodevelopment from conception onwards, but there is no evaluation of the impact of multiple groups of exposures simultaneously. We investigated the association between early-life urban environment and cognitive and motor function in children. Methods: We used data from 5403 mother-child pairs from four population-based birth-cohorts (UK, France, Spain, and Greece). We estimated thirteen urban home exposures during pregnancy and childhood, including: built environment, natural spaces, and air pollution. Verbal, non-verbal, gross motor, and fine motor functions were assessed using validated tests at five years old. We ran adjusted multi-exposure models using the Deletion-Substitution-Addition algorithm. Results: Higher greenness exposure within 300 m during pregnancy was associated with higher verbal abilities (1.5 points (95% confidence interval 0.4, 2.7) per 0.20 unit increase in greenness). Higher connectivity density within 100 m and land use diversity during pregnancy were related to lower verbal abilities. Childhood exposure to PM2.5 mediated 74% of the association between greenness during childhood and verbal abilities. Higher exposure to PM2.5 during pregnancy was related to lower fine motor function (-1.2 points (-2.1, -0.4) per 3.2 mu g/m3 increase in PM2.5). No associations were found with non-verbal abilities and gross motor function. Discussion: This study suggests that built environment, greenness, and air pollution may impact child cognitive and motor function at five years old. This study adds evidence that well-designed urban planning may benefit children's cognitive and motor development.
ACU Research Bank arrow_drop_down HAL-Rennes 1; HAL-Inserm; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022License: CC BY NC NDFull-Text: https://hal.science/hal-03480282/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 24 citations 24 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert ACU Research Bank arrow_drop_down HAL-Rennes 1; HAL-Inserm; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022License: CC BY NC NDFull-Text: https://hal.science/hal-03480282/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2021 FrancePublisher:Oxford University Press (OUP) Funded by:EC | ENERXICOEC| ENERXICOJian Cao; Romain Brossier; Andrzej Górszczyk; Ludovic Métivier; Jean Virieux;doi: 10.1093/gji/ggab484
SUMMARYOcean-bottom seismic acquisition systems deployed on the seabed give access to three-component geophone data and hydrophone data. Compared with conventional streamer acquisitions, the separation of sources and receivers makes it possible to increase the maximum offset and azimuth coverage for improving the illumination at depth. Furthermore, the three-component geophones naturally capture elastic wave propagation effects. While this information is mostly overlooked up to now, reconstructing jointly P- and S-wave velocities would significantly improve the subsurface characterization. To achieve a 3-D high-resolution multiparameter reconstruction, we design an efficient 3-D fluid–solid coupled full waveform modelling and inversion engine. In this engine, fluid and solid domains are divided explicitly and handled with the acoustic and elastic wave equations, respectively. The numerical implementation is based on a time-domain spectral-element method (SEM) with a flexible 3-D Cartesian-based hexahedral mesh, which contributes to an accurate coupling of the acoustic and elastic wave equations and high computational efficiency through domain-decomposition based parallelization. We select the best acoustic–elastic coupled formulations among 4 possibilities with criteria based on numerical accuracy and implementation efficiency. Moreover, we propose a specific hybrid approach for the misfit gradient building so as to use a similar modelling solver for both forward and adjoint simulations. Synthetic case studies on a 3-D extended Marmousi-II model and a 3-D deep-water crustal-scale model illustrate how our modelling and inversion engine can efficiently extract information from ocean-bottom seismic data to simultaneously reconstruct both P- and S-wave velocities within a full waveform inversion framework.
Geophysical Journal ... arrow_drop_down Geophysical Journal InternationalArticle . 2021 . Peer-reviewedLicense: OUP Standard Publication ReuseData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/gji/ggab484&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess Routeshybrid 9 citations 9 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Geophysical Journal ... arrow_drop_down Geophysical Journal InternationalArticle . 2021 . Peer-reviewedLicense: OUP Standard Publication ReuseData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.1093/gji/ggab484&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article , Preprint 2021 France, Germany, France, FrancePublisher:Copernicus GmbH Funded by:NSF | Collaborative Research: C..., EC | CRESCENDO, NSERC +1 projectsNSF| Collaborative Research: Carbon, Water, and Energy Balance of the Arctic Landscape at Flagship Observatories in Alaska and Siberia ,EC| CRESCENDO ,NSERC ,NSF| Collaborative Research on Carbon, Water, and Energy Balance of the Arctic Landscape at Flagship Observatories in Alaska and SiberiaElodie Salmon; Fabrice Jégou; Bertrand Guenet; Line Jourdain; Chunjing Qiu; Vladislav Bastrikov; Christophe Guimbaud; Dan Zhu; Philippe Ciais; Philippe Peylin; Sébastien Gogo; Fatima Laggoun-Défarge; Mika Aurela; M. Syndonia Bret-Harte; Jiquan Chen; Bogdan H. Chojnicki; Housen Chu; C. Edgar; Eugénie S. Euskirchen; Lawrence B. Flanagan; Krzysztof Fortuniak; David Holl; Janina Klatt; Olaf Kolle; Natalia Kowalska; Lars Kutzbach; Annalea Lohila; Lutz Merbold; Włodzimierz Pawlak; Torsten Sachs; Klaudia Ziemblińska;In the global methane budget, the largest natural source is attributed to wetlands, which encompass all ecosystems composed of waterlogged or inundated ground, capable of methane production. Among them, northern peatlands that store large amounts of soil organic carbon have been functioning, since the end of the last glaciation period, as long-term sources of methane (CH4) and are one of the most significant methane sources among wetlands. To reduce uncertainty of quantifying methane flux in the global methane budget, it is of significance to understand the underlying processes for methane production and fluxes in northern peatlands. A methane model that features methane production and transport by plants, ebullition process and diffusion in soil, oxidation to CO2, and CH4 fluxes to the atmosphere has been embedded in the ORCHIDEE-PEAT land surface model that includes an explicit representation of northern peatlands. ORCHIDEE-PCH4 was calibrated and evaluated on 14 peatland sites distributed on both the Eurasian and American continents in the northern boreal and temperate regions. Data assimilation approaches were employed to optimized parameters at each site and at all sites simultaneously. Results show that methanogenesis is sensitive to temperature and substrate availability over the top 75 cm of soil depth. Methane emissions estimated using single site optimization (SSO) of model parameters are underestimated by 9 g CH4 m−2 yr−1 on average (i.e., 50 % higher than the site average of yearly methane emissions). While using the multi-site optimization (MSO), methane emissions are overestimated by 5 g CH4 m−2 yr−1 on average across all investigated sites (i.e., 37 % lower than the site average of yearly methane emissions).
Geoscientific Model ... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2021Data sources: Copernicus PublicationsGFZ German Research Centre for GeosciencesArticle . 2022License: CC BYData sources: GFZ German Research Centre for GeosciencesGeoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus Publicationshttps://doi.org/10.5194/gmd-20...Preprint . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefHAL Descartes; Mémoires en Sciences de l'Information et de la Communication; HAL-CEAArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/gmd-2021-280&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 7 citations 7 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Geoscientific Model ... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2021Data sources: Copernicus PublicationsGFZ German Research Centre for GeosciencesArticle . 2022License: CC BYData sources: GFZ German Research Centre for GeosciencesGeoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus Publicationshttps://doi.org/10.5194/gmd-20...Preprint . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefHAL Descartes; Mémoires en Sciences de l'Information et de la Communication; HAL-CEAArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.All Research productsarrow_drop_down <script type="text/javascript"> <!-- document.write('<div id="oa_widget"></div>'); document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=10.5194/gmd-2021-280&type=result"></script>'); --> </script>
For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2021 Italy, France, Belgium, ItalyPublisher:American Astronomical Society Funded by:ANR | e-PYTHEAS, EC | ExoAI, EC | ExoMAC +5 projectsANR| e-PYTHEAS ,EC| ExoAI ,EC| ExoMAC ,EC| ATMO ,UKRI| ARIEL SCIENCE ADVISORY TEAM UK ACTIVITIES ,UKRI| UCL Centre for Doctoral Training in Data Intensive Science and Technologies ,EC| WHIPLASH ,EC| ExoplANETS ALorenzo V. Mugnai; Darius Modirrousta-Galian; Billy Edwards; Quentin Changeat; Jeroen Bouwman; Giuseppe Morello; Ahmed Al-Refaie; Robin Baeyens; Michelle Fabienne Bieger; Doriann Blain; Amélie Gressier; Gloria Guilluy; Yassin Jaziri; Flavien Kiefer; Mario Morvan; William Pluriel; Mathilde Poveda; Nour Skaf; Niall Whiteford; Sam Wright; Kai Hou Yip; Tiziano Zingales; Benjamin Charnay; Pierre Drossart; Jérémy Leconte; Olivia Venot; Ingo Waldmann; Jean-Philippe Beaulieu;handle: 11577/3415977 , 11573/1549763
We present a study on the spatially scanned spectroscopic observations of the transit of GJ 1132 b, a warm ($\sim$500 K) Super-Earth (1.13 R$_\oplus$) that was obtained with the G141 grism (1.125 - 1.650 $\mu$m) of the Wide Field Camera 3 (WFC3) onboard the Hubble Space Telescope. We used the publicly available Iraclis pipeline to extract the planetary transmission spectra from the five visits and produce a precise transmission spectrum. We analysed the spectrum using the TauREx3 atmospheric retrieval code with which we show that the measurements do not contain molecular signatures in the investigated wavelength range and are best-fit with a flat-line model. Our results suggest that the planet does not have a clear primordial, hydrogen-dominated atmosphere. Instead, GJ 1132 b could have a cloudy hydrogen-dominated envelope, a very enriched secondary atmosphere, be airless, or have a tenuous atmosphere that has not been detected. Due to the narrow wavelength coverage of WFC3, these scenarios cannot be distinguished yet but the James Webb Space Telescope may be capable of detecting atmospheric features, although several observations may be required to provide useful constraints. Comment: 17 pages, 11 figures. Accepted for publication in AJ
Archivio della ricer... arrow_drop_down Archivio istituzionale della ricerca - Università di Padova; The Astronomical JournalOther literature type . Article . 2021 . Peer-reviewedLicense: IOP Copyright PoliciesArchivio della ricerca- Università di Roma La SapienzaArticle . 2021Data sources: Archivio della ricerca- Università di Roma La SapienzaHAL - UPEC / UPEM; Hal-DiderotArticle . 2021add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 38 citations 38 popularity Top 1% influence Average impulse Top 1% Powered by BIP!visibility 25visibility views 25 Powered bymore_vert Archivio della ricer... arrow_drop_down Archivio istituzionale della ricerca - Università di Padova; The Astronomical JournalOther literature type . Article . 2021 . Peer-reviewedLicense: IOP Copyright PoliciesArchivio della ricerca- Università di Roma La SapienzaArticle . 2021Data sources: Archivio della ricerca- Università di Roma La SapienzaHAL - UPEC / UPEM; Hal-DiderotArticle . 2021add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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description Publicationkeyboard_double_arrow_right Article 2023 France, Belgium, Italy, Spain, Sweden, United Kingdom, Sweden, PolandPublisher:Elsevier BV Funded by:EC | ALECEC| ALECTianyu Zhao; Iana Markevych; Elaine Fuertes; Kees de Hoogh; Simone Accordini; Anne Boudier; Lidia Casas; Bertil Forsberg; Judith Garcia Aymerich; Marco Gnesi; Mathias Holm; Christer Janson; Deborah Jarvis; Ane Johannessen; Rudolf A. Jörres; Stefan Karrasch; Benedicte Leynaert; José Antonio Maldonado Perez; Andrei Malinovschi; Jesús Martínez-Moratalla; Lars Modig; Dennis Nowak; James Potts; Nicole Probst-Hensch; José Luis Sánchez-Ramos; Valerie Siroux; Isabel Urrutia Landa; Danielle Vienneau; Simona Villani; Bénédicte Jacquemin; Joachim Heinrich;Background: While the adverse effects of short-term ambient ozone exposure on lung function are well-documented, the impact of long-term exposure remains poorly understood, especially in adults. Methods: We aimed to investigate the association between long-term ozone exposure and lung function decline. The 3014 participants were drawn from 17 centers across eight countries, all of which were from the European Community Respiratory Health Survey (ECRHS). Spirometry was conducted to measure pre-bronchodilation forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) at approximately 35, 44, and 55 years of age. We assigned annual mean values of daily maximum running 8-h average ozone concentrations to individual residential addresses. Adjustments were made for PM2.5, NO2, and greenness. To capture the ozone-related change in spirometric parameters, our linear mixed effects regression models included an interaction term between long-term ozone exposure and age. Findings: Mean ambient ozone concentrations were approximately 65 μg/m³. A one interquartile range increase of 7 μg/m³ in ozone was associated with a faster decline in FEV1 of -2.08 mL/year (95% confidence interval: -2.79, -1.36) and in FVC of -2.86 mL/year (-3.73, -1.99) mL/year over the study period. Associations were robust after adjusting for PM2.5, NO2, and greenness. The associations were more pronounced in residents of northern Europe and individuals who were older at baseline. No consistent associations were detected with the FEV1/FVC ratio. Interpretation: Long-term exposure to elevated ambient ozone concentrations was associated with a faster decline of spirometric lung function among middle-aged European adults over a 20-year period. Funding: German Research Foundation. The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study (www.alecstudy.org), which has also received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health are reported in the Supplementary Material.
IRIS - Università de... arrow_drop_down IRIS - Università degli Studi di Verona; The Lancet Regional Health. EuropeArticle . 2023 . Peer-reviewedLicense: CC BYIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaSpiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryThe Lancet Regional Health. EuropeArticle . 2023Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 0 citations 0 popularity Average influence Average impulse Average Powered by BIP!more_vert IRIS - Università de... arrow_drop_down IRIS - Università degli Studi di Verona; The Lancet Regional Health. EuropeArticle . 2023 . Peer-reviewedLicense: CC BYIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaSpiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryThe Lancet Regional Health. EuropeArticle . 2023Data sources: Institutional Repository Universiteit Antwerpenadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2023 France, Sweden, Poland, Italy, Sweden, Italy, Belgium, Spain, Norway, United Kingdom, SwitzerlandPublisher:Elsevier BV Funded by:EC | ALECEC| ALECIana Markevych; Tianyu Zhao; Elaine Fuertes; Alessandro Marcon; Payam Dadvand; Danielle Vienneau; Judith Garcia Aymerich; Dennis Nowak; Kees de Hoogh; Deborah Jarvis; Michael J. Abramson; Simone Accordini; Andre FS Amaral; Hayat Bentouhami; Randi Jacobsen Bertelsen; Anne Boudier; Roberto Bono; Gayan Bowatte; Lidia Casas; Shyamali C Dharmage; Bertil Forsberg; Thorarinn Gislason; Marco Gnesi; Mathias Holm; Benedicte Jacquemin; Christer Janson; Rain Jogi; Ane Johannessen; Dirk Keidel; Benedicte Leynaert; José Antonio Maldonado Perez; Pierpaolo Marchetti; Enrica Migliore; Jesús Martínez-Moratalla; Hans Orru; Isabelle Pin; James Potts; Nicole Probst-Hensch; Andrea Ranzi; José Luis Sánchez-Ramos; Valerie Siroux; David Soussan; Jordi Sunyer; Isabel Urrutia Landa; Simona Villani; Joachim Heinrich;handle: 2318/1913411 , 10067/1971420151162165141 , 11562/1097567 , 11250/3115606
pmid: 37336027
Background: The few studies that have examined associations between greenspace and lung function in adulthood have yielded conflicting results and none have examined whether the rate of lung function decline is affected. Objective: We explored the association between residential greenspace and change in lung function over 20 years in 5559 adults from 22 centers in 11 countries participating in the population-based, international European Community Respiratory Health Survey. Methods: Forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) were measured by spirometry when participants were approximately 35 (1990-1994), 44 (1999-2003), and 55 (2010-2014) years old. Greenness was assessed as the mean Normalized Difference Vegetation Index (NDVI) in 500 m, 300 m, and 100 m circular buffers around the residential addresses at the time of lung function measurement. Green spaces were defined as the presence of agricultural, natural, or urban green spaces in a circular 300 m buffer. Associations of these greenspace parameters with the rate of lung function change were assessed using adjusted linear mixed effects regression models with random intercepts for subjects nested within centers. Sensitivity analyses considered air pollution exposures. Results: A 0.2-increase (average interquartile range) in NDVI in the 500 m buffer was consistently associated with a faster decline in FVC (-1.25 mL/year [95% confidence interval: -2.18 to -0.33]). These associations were especially pronounced in females and those living in areas with low PM10 levels. We found no consistent associations with FEV1 and the FEV1/FVC ratio. Residing near forests or urban green spaces was associated with a faster decline in FEV1, while agricultural land and forests were related to a greater decline in FVC. Conclusions: More residential greenspace was not associated with better lung function in middle-aged European adults. Instead, we observed slight but consistent declines in lung function parameters. The potentially detrimental association requires verification in future studies. The present analyses are part of the Ageing Lungs in European Cohorts (ALEC) Study (https://www.alecstudy.org), which has also received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 633212. The local investigators and funding agencies for the European Community Respiratory Health are reported in the Supplementary Material. ISGlobal is a member of CERCA Programme/Generalitat de Catalunya. These sources of funding had no role in the study design, the collection, analysis and interpretation of data, the writing of the report, and in the decision to submit the article for publication.
Archivio Istituziona... arrow_drop_down Spiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryEnvironment InternationalArticle . 2023Data sources: Institutional Repository Universiteit AntwerpenIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaBergen Open Research Archive - UiB; Norwegian Open Research ArchivesArticle . 2023 . Peer-reviewedLicense: CC BYHAL-Rennes 1; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2023License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 1 citations 1 popularity Average influence Average impulse Average Powered by BIP!visibility 1visibility views 1 download downloads 3 Powered bymore_vert Archivio Istituziona... arrow_drop_down Spiral - Imperial College Digital RepositoryArticle . 2023License: CC BYData sources: Spiral - Imperial College Digital RepositoryEnvironment InternationalArticle . 2023Data sources: Institutional Repository Universiteit AntwerpenIRIS - Università degli Studi di VeronaArticle . 2023Data sources: IRIS - Università degli Studi di VeronaBergen Open Research Archive - UiB; Norwegian Open Research ArchivesArticle . 2023 . Peer-reviewedLicense: CC BYHAL-Rennes 1; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2023License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 France, Italy, PolandPublisher:Elsevier BV Funded by:EC | ALEC, NIH | COMMUNITY BASED STUDY ON ...EC| ALEC ,NIH| COMMUNITY BASED STUDY ON OCCUPATIONAL ASTHMA, ECRHS-OAAnne, Boudier; Iana, Markevych; Bénédicte, Jacquemin; Michael J, Abramson; Simone, Accordini; Bertil, Forsberg; Elaine, Fuertes; Judith, Garcia-Aymerich; Joachim, Heinrich; Ane, Johannessen; Bénédicte, Leynaert; Isabelle, Pin; Valérie, Siroux;International audience; BACKGROUND: Associations of long-term exposure to air pollution and greenspace with health-related quality of life (HRQOL) are poorly studied and few studies have accounted for asthma-rhinitis status. OBJECTIVE: To assess the associations of air pollution and greenspace with HRQOL and whether asthma and/or rhinitis modify these associations. METHODS: The study was based on the participants in the second (2000-2002, n = 6542) and third (2011-2013, n = 3686) waves of the European Community Respiratory Health Survey (ECRHS) including 19 centres. The mean follow-up time was 11.3 years. HRQOL was assessed by the SF-36 Physical and Mental Component Summary scores (PCS and MCS). NO(2), PM(2.5) and PM(10) annual concentrations were estimated at the residential address from existing land-use regression models. Greenspace around the residential address was estimated by the (i) mean of the Normalized Difference Vegetation Index (NDVI) and by the (ii) presence of green spaces within a 300 m buffer. Associations of each exposure variable with PCS and MCS were assessed by mixed linear regression models, accounting for the multicentre design and repeated data, and adjusting for potential confounders. Analyses were stratified by asthma-rhinitis status. RESULTS: The mean (SD) age of the ECRHS-II and III participants was 43 (7.1) and 54 (7.2) years, respectively, and 48 % were men. Higher NO(2), PM(2.5) and PM(10) concentrations were associated with lower MCS (regression coefficients [95%CI] for one unit increase in the inter-quartile range of exposures were -0.69 [-1.23; -0.15], -1.79 [-2.88; -0.70], -1.80 [-2.98; -0.62] respectively). Higher NDVI and presence of forests were associated with higher MCS. No consistent associations were observed for PCS. Similar association patterns were observed regardless of asthma-rhinitis status. CONCLUSION: European adults who resided at places with higher air pollution and lower greenspace were more likely to have lower mental component of HRQOL. Asthma or rhinitis status did not modify these associations.
Jagiellonian Univers... arrow_drop_down IRIS - Università degli Studi di VeronaArticle . 2022Data sources: IRIS - Università degli Studi di VeronaThe Science of The Total Environment; IRIS - Università degli Studi di VeronaArticle . 2022 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu6 citations 6 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Jagiellonian Univers... arrow_drop_down IRIS - Università degli Studi di VeronaArticle . 2022Data sources: IRIS - Università degli Studi di VeronaThe Science of The Total Environment; IRIS - Università degli Studi di VeronaArticle . 2022 . Peer-reviewedLicense: Elsevier TDMadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Australia, France, Spain, NorwayPublisher:Elsevier BV Funded by:WT | The Born in Bradford (BiB..., EC | ENRIECO, EC | ATHLETE +5 projectsWT| The Born in Bradford (BiB) Study an international biomedical resource for exploring genetic and early life determinants of health and development in a deprived multi-ethnic population. ,EC| ENRIECO ,EC| ATHLETE ,EC| ESCAPE ,EC| HELIX ,EC| CHICOS ,EC| ENVIROGENOMARKERS ,EC| LIFECYCLEde Prado-Bert, Paula; Warembourg, Charline; Dedele, Audrius; Heude, Barbara; Borràs, Eva; Sabidó, Eduard; Aasvang, Gunn Marit; Lepeule, Johanna; Wright, John; Urquiza, Jose; Gützkow, Kristine B.; Maitre, Léa; Chatzi, Leda; Casas, Maribel; Vafeiadi, Marina; Nieuwenhuijsen, Mark J.; de Castro, Montserrat; Grazuleviciene, Regina; McEachan, Rosemary R.C.; Basagaña, Xavier; Vrijheid, Martine; Sunyer, Jordi; Bustamante, Mariona;pmid: 35292243
Exposure to air pollution influences children's health, however, the biological mechanisms underlying these effects are not completely elucidated. We investigated the association between short- and medium-term outdoor air pollution exposure with protein profiles and their link with blood pressure in 1170 HELIX children aged 6-11 years. Different air pollutants (NO2, PM10, PM2.5, and PM2.5abs) were estimated based on residential and school addresses at three different windows of exposure (1-day, 1-week, and 1-year before clinical and molecular assessment). Thirty-six proteins, including adipokines, cytokines, or apolipoproteins, were measured in children's plasma using Luminex. Systolic and diastolic blood pressure (SBP and DBP) were measured following a standardized protocol. We performed an association study for each air pollutant at each location and time window and each outcome, adjusting for potential confounders. After correcting for multiple-testing, hepatocyte growth factor (HGF) and interleukin 8 (IL8) levels were positively associated with 1-week home exposure to some of the pollutants (NO2, PM10, or PM2.5). NO2 1-week home exposure was also related to higher SBP. The mediation study suggested that HGF could explain 19% of the short-term effect of NO2 on blood pressure, but other study designs are needed to prove the causal directionality between HGF and blood pressure. The study received funding from the European Community’s Seventh Framework Programme (FP7/2007–206) (grant agreement no 308333) (HELIX project), the H2020-EU.3.1.2. - Preventing Disease Programme (grant agreement no 874583) (ATHLETE project) and from the European Union’s Horizon 2020 research and innovation programme (grant Agreement number: 733206) (Early Life stressors and Lifecycle Health (LIFECYCLE)). BiB received funding from the Welcome Trust (WT101597MA), from the UK Medical Research Council (MRC) and Economic and Social Science Research Council (ESRC) (MR/N024397/ 1). The study was supported by the European Union FP7 programmes (FP7/ 2007–2013, HELIX, ESCAPE, ENRIECO, Medall projects). INMA was supported by grants from the Instituto de Salud Carlos III, CIBERESP, and the Generalitat de Catalunya-CIRIT. KANC was funded by the grant of the Lithuanian Agency for Science Innovation and Technology (6-04-2014_31V-66). The Rhea project was financially supported by European projects (EU FP6-2003-Food-3-NewGeneris, EU FP6. STREP Hiwate, EU FP7 ENV. 2007.1.2.2.2. Project No 211250 Escape, EU FP7- 2008-ENV-1.2.1.4 Envirogenomarkers, EU FP7-HEALTH-2009- single stage CHICOS, EU FP7 ENV. 2008.1.2.1.6. Proposal No 226285 ENRIECO, EU- FP7- HEALTH-2012 Proposal No 308333 HELIX). MC received funding from Instituto Carlos III (Ministry of Economy and Competitiveness) (CD12/00563 and MS16/00128). JU is supported by Spanish regional program PERIS (Ref.: SLT017/20/ 000119) Granted by Departament de Salut de la Generalitat de Catalunya. The CRG/UPF Proteomics Unit is part of the Spanish Infrastructure for Omics Technologies (ICTS OmicsTech) and it is member of the ProteoRed PRB3 consortium which is supported by grant PT17/0019 of the PE I + D + i 2013–2016 from the Instituto de Salud Carlos III (ISCIII)
ACU Research Bank arrow_drop_down Norwegian Institute of Public Health Open RepositoryArticle . 2022Data sources: Norwegian Institute of Public Health Open Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routeshybrid 5 citations 5 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert ACU Research Bank arrow_drop_down Norwegian Institute of Public Health Open RepositoryArticle . 2022Data sources: Norwegian Institute of Public Health Open Repositoryadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Other literature type 2022 France, France, France, France, GermanyPublisher:Copernicus GmbH Funded by:EC | IMMERSE, NSF | EarthCube Data Capabiliti..., NSF | NSFGEO-NERC: Collaborativ... +3 projectsEC| IMMERSE ,NSF| EarthCube Data Capabilities: A Cloud-Native Data Repository for the Geoscience Community ,NSF| NSFGEO-NERC: Collaborative Research: Assessing the influence of sub-annual variability in the AMOC on the Gulf Stream and the atmosphere ,ANR| CONTACTS ,ANR| DEEPER ,EC| ESiWACE2T. Uchida; J. Le Sommer; C. Stern; R. P. Abernathey; C. Holdgraf; A. Albert; L. Brodeau; L. Brodeau; E. P. Chassignet; X. Xu; J. Gula; J. Gula; G. Roullet; N. Koldunov; S. Danilov; Q. Wang; D. Menemenlis; C. Bricaud; B. K. Arbic; J. F. Shriver; F. Qiao; B. Xiao; A. Biastoch; A. Biastoch; R. Schubert; R. Schubert; B. Fox-Kemper; W. K. Dewar; W. K. Dewar; A. Wallcraft;Abstract. With the increase in computational power, ocean models with kilometer-scale resolution have emerged over the last decade. These models have been used for quantifying the energetic exchanges between spatial scales, informing the design of eddy parametrizations, and preparing observing networks. The increase in resolution, however, has drastically increased the size of model outputs, making it difficult to transfer and analyze the data. It remains, nonetheless, of primary importance to assess more systematically the realism of these models. Here, we showcase a cloud-based analysis framework proposed by the Pangeo project that aims to tackle such distribution and analysis challenges. We analyze the output of eight submesoscale-permitting simulations, all on the cloud, for a crossover region of the upcoming Surface Water and Ocean Topography (SWOT) altimeter mission near the Gulf Stream separation. The cloud-based analysis framework (i) minimizes the cost of duplicating and storing ghost copies of data and (ii) allows for seamless sharing of analysis results amongst collaborators. We describe the framework and provide example analyses (e.g., sea-surface height variability, submesoscale vertical buoyancy fluxes, and comparison to predictions from the mixed-layer instability parametrization). Basin- to global-scale, submesoscale-permitting models are still at their early stage of development; their cost and carbon footprints are also rather large. It would, therefore, benefit the community to document the different model configurations for future best practices. We also argue that an emphasis on data analysis strategies would be crucial for improving the models themselves.
OceanRep; Geoscienti... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus PublicationsElectronic Publication Information CenterArticle . 2022Data sources: Electronic Publication Information CenterArchiMer - Institutional Archive of IfremerOther literature type . 2022Data sources: ArchiMer - Institutional Archive of IfremerINRIA a CCSD electronic archive server; Mémoires en Sciences de l'Information et de la Communication; HAL-IRDArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesgold 8 citations 8 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert OceanRep; Geoscienti... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus PublicationsElectronic Publication Information CenterArticle . 2022Data sources: Electronic Publication Information CenterArchiMer - Institutional Archive of IfremerOther literature type . 2022Data sources: ArchiMer - Institutional Archive of IfremerINRIA a CCSD electronic archive server; Mémoires en Sciences de l'Information et de la Communication; HAL-IRDArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Italy, FrancePublisher:American Institute of Aeronautics and Astronautics (AIAA) Funded by:EC | ICE GENESIS, EC | UTOPIAEEC| ICE GENESIS ,EC| UTOPIAEGiulio Gori; Pietro Marco Congedo; Olivier Le Maitre; Tommaso Bellosta; Alberto Guardone;doi: 10.2514/1.c036545
handle: 11311/1191613
International audience; In-flight ice accretion under parametric uncertainty is investigated. Three test cases are presented which reproduce experiments carried out at the NASA's Glenn Icing Research Tunnel (IRT) facility. A preliminary accuracy assessment, achieved comparing numerical predictions against experimental observations, confirm the robustness and the predictiveness of the computerized icing model. Besides, sensitivity analyses highlight the variance of the targeted outputs with respect to the different uncertain inputs. In rime icing conditions, a predominant role is played by the uncertainty affecting the airfoil angle of attack, the cloud liquid water content and the droplets’ mean volume diameter. In glaze icing condition, the sensitivity analysis shows instead that the output variability is due mainly to the ambient temperature uncertainty. Results expose a major criticality of standard uncertainty quantification techniques. The issue is inherent the approximation of the full icing model behavior in domain regions scarcely affected by ice build up. To mitigate the issue, a non-linear regression method is proposed and applied.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routesbronze 2 citations 2 popularity Top 10% influence Average impulse Average Powered by BIP!more_vert add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2022 Spain, Spain, Spain, Netherlands, France, France, Australia, FrancePublisher:Elsevier BV Funded by:WT | The Born in Bradford (BiB..., NIH | Effects of DDE exposure o..., NIH | Pilot Project Program +6 projectsWT| The Born in Bradford (BiB) Study an international biomedical resource for exploring genetic and early life determinants of health and development in a deprived multi-ethnic population. ,NIH| Effects of DDE exposure on adipose tissue function, weight loss and metabolic improvement after bariatric surgery: A new paradigm for study of lipophilic chemicals ,NIH| Pilot Project Program ,NIH| Hepatotoxic effects of perfluoroalkyl substances: a new epidemiological approach for studying environmental fatty liver disease ,EC| EUCAN-Connect ,NIH| Environmental Chemical Exposures and Longitudinal Changes of Glucose Metabolism, Insulin Sensitivity and B Cell Function in Youth ,NHMRC| An evaluation of bone density screening in premenopausal women ,EC| DENAMIC ,EC| HELIXAuthors: Binter, Anne-Claire; Bernard, Jonathan Y.; Mon-Williams, Mark; Andiarena, Ainara; +15 AuthorsBinter, Anne-Claire; Bernard, Jonathan Y.; Mon-Williams, Mark; Andiarena, Ainara; González-Safont, Llúcia; Vafeiadi, Marina; Lepeule, Johanna; Soler-Blasco, Raquel; Alonso, Lucia; Kampouri, Mariza; Mceachan, Rosie; Santa-Marina, Loreto; Wright, John; Chatzi, Leda; Sunyer, Jordi; Philippat, Claire; Nieuwenhuijsen, Mark; Vrijheid, Martine; Guxens, Mònica;Acknowledgements We are grateful to all the participating children, parents, practi-tioners and researchers in the four countries who took part in this study. This work was supported by funding from the European Community's Seventh Framework Programme [FP7/2007-206 n 308333; the HELIX project] . This INMA cohort was funded by grants from Instituto de Salud Carlos III (Red INMA G03/176; CB06/02/0041; PI041436; PI081151 incl. FEDER funds, FIS PI06/0867, FIS-PI09/00090, FIS and FIS-PI18/01142 incl. FEDER funds, FIS-FEDER: PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI09/02647, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/2032, PI14/00891, PI14/01687, PI16/1288, PI16/00118 and PI17/00663; FIS-FSE: 17/00260; Miguel Servet-FEDER CP11/00178, CP15/00025, CPII16/00051, and CPII18/00018) , from UE (FP7-ENV-2011 cod 282957, HEALTH.2010.2.4.5-1, and H2020 n 824989) , Generalitat de Catalunya-CIRIT 1999SGR 00241, Fundacio La marato de TV3 (090430) , Generalitat Valenciana: FISABIO (UGP 15-230, UGP-15-244, and UGP-15-249) , Alicia Koplowitz Foundation 2017, CIBERESP, Department of Health of the Basque Government (2013111089, 2009111069, 2013111089, 2015111065 and 2018111086) , Provincial Government of Gipuzkoa (DFG06/002, DFG08/001, DFG15/221 and DFG 89/17) and annual agreements with the municipalities of the study area (Zumarraga, Urretxu , Legazpi, Azkoitia y Azpeitia y Beasain) . We acknowledge support from the Spanish Ministry of Science and Inno-vation and the State Research Agency through the "Centro de Excelencia Severo Ochoa 2019-2023" Program (CEX2018-000806-S) , and support from the Generalitat de Catalunya through the CERCA Program. The work was also supported by MICINN [MTM2015-68140-R] and Centro Nacional de Genotipado-CEGEN-PRB2-ISCIII (Spain) . The Rhea project was financially supported by European projects, and the Greek Ministry of Health (Program of Prevention of obesity and neurodevelopmental disorders in preschool children, in Heraklion district, Crete, Greece: 2011-2014; "Rhea Plus": Primary Prevention Program of Environmental Risk Factors for Reproductive Health, and Child Health: 2012-15) . This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Collaboration for Applied Health Research and Care (CLAHRC) for Yorkshire and Humber (UK) . The EDEN study was supported by Foundation for medical research (FRM) , National Agency for Research (ANR) , National Institute for Research inPublic health (IRESP: TGIR cohorte sante 2008 program) , French Min-istry of Health (DGS) , French Ministry of Research, INSERM Bone and Joint Diseases National Research (PRO-A) , and Human Nutrition Na-tional Research Programs, Paris-Sud University, Nestle, French National Institute for Population Health Surveillance (InVS) , French National Institute for Health Education (INPES) , the European Union FP7 pro-grams (ESCAPE, ENRIECO, Medall projects) , Diabetes National Research Program (through a collaboration with the French Association of Diabetic Patients (AFD) ) , French Agency for Environmental Health Safety and French National Agency for Food Security (now ANSES) , Mutuelle Generale de l'Education Nationale a complementary health insurance (MGEN) , French-speaking association for the study of diabetes and metabolism (ALFEDIAM) . Core support for Born in Bradford is also provided by the Wellcome Trust (WT101597MA, UK) . Born in Bradford (BiB) is only possible because of the enthusiasm and commitment of the children and parents in BiB. We are grateful to all the participants, health professionals, schools and researchers who have made BiB happen. BiB receives funding from the ESRC/MRC, the Wellcome Trust (WT101597MA) and the National Institute for Health Research York-shire and Humber ARC (reference: NIHR20016) . M. Mon-Williams was supported by a Fellowship from the Alan Turing Institute. Additional funding from the National Institute of Environmental Health Science supported Dr Chatzi (R01ES030691, R01ES029944, R01ES030364, R21ES029681, and P30ES007048) . The views expressed are those of the authors, and not necessarily those of the NHS or the NIHR. None of the funders were involved in designing the study, collecting the data, analyzing or interpreting the data, deciding to submit the article for publication, or the writing of the report. Data sharing statement The HELIX data warehouse has been established as an accessible resource for collaborative research involving researchers external to the project. Access to HELIX data is based on approval by the HELIX Project Executive Committee and by the individual cohorts. Further details on the content of the data warehouse (data catalogue) and procedures for external access are described on the project website (http:// www.proj-ecthelix.eu/index.php/es/data-inventory) . [EN]Background: The urban environment may influence neurodevelopment from conception onwards, but there is no evaluation of the impact of multiple groups of exposures simultaneously. We investigated the association between early-life urban environment and cognitive and motor function in children. Methods: We used data from 5403 mother-child pairs from four population-based birth-cohorts (UK, France, Spain, and Greece). We estimated thirteen urban home exposures during pregnancy and childhood, including: built environment, natural spaces, and air pollution. Verbal, non-verbal, gross motor, and fine motor functions were assessed using validated tests at five years old. We ran adjusted multi-exposure models using the Deletion-Substitution-Addition algorithm. Results: Higher greenness exposure within 300 m during pregnancy was associated with higher verbal abilities (1.5 points (95% confidence interval 0.4, 2.7) per 0.20 unit increase in greenness). Higher connectivity density within 100 m and land use diversity during pregnancy were related to lower verbal abilities. Childhood exposure to PM2.5 mediated 74% of the association between greenness during childhood and verbal abilities. Higher exposure to PM2.5 during pregnancy was related to lower fine motor function (-1.2 points (-2.1, -0.4) per 3.2 mu g/m3 increase in PM2.5). No associations were found with non-verbal abilities and gross motor function. Discussion: This study suggests that built environment, greenness, and air pollution may impact child cognitive and motor function at five years old. This study adds evidence that well-designed urban planning may benefit children's cognitive and motor development.
ACU Research Bank arrow_drop_down HAL-Rennes 1; HAL-Inserm; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022License: CC BY NC NDFull-Text: https://hal.science/hal-03480282/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 24 citations 24 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert ACU Research Bank arrow_drop_down HAL-Rennes 1; HAL-Inserm; Mémoires en Sciences de l'Information et de la CommunicationArticle . 2022License: CC BY NC NDFull-Text: https://hal.science/hal-03480282/documentadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article 2021 FrancePublisher:Oxford University Press (OUP) Funded by:EC | ENERXICOEC| ENERXICOJian Cao; Romain Brossier; Andrzej Górszczyk; Ludovic Métivier; Jean Virieux;doi: 10.1093/gji/ggab484
SUMMARYOcean-bottom seismic acquisition systems deployed on the seabed give access to three-component geophone data and hydrophone data. Compared with conventional streamer acquisitions, the separation of sources and receivers makes it possible to increase the maximum offset and azimuth coverage for improving the illumination at depth. Furthermore, the three-component geophones naturally capture elastic wave propagation effects. While this information is mostly overlooked up to now, reconstructing jointly P- and S-wave velocities would significantly improve the subsurface characterization. To achieve a 3-D high-resolution multiparameter reconstruction, we design an efficient 3-D fluid–solid coupled full waveform modelling and inversion engine. In this engine, fluid and solid domains are divided explicitly and handled with the acoustic and elastic wave equations, respectively. The numerical implementation is based on a time-domain spectral-element method (SEM) with a flexible 3-D Cartesian-based hexahedral mesh, which contributes to an accurate coupling of the acoustic and elastic wave equations and high computational efficiency through domain-decomposition based parallelization. We select the best acoustic–elastic coupled formulations among 4 possibilities with criteria based on numerical accuracy and implementation efficiency. Moreover, we propose a specific hybrid approach for the misfit gradient building so as to use a similar modelling solver for both forward and adjoint simulations. Synthetic case studies on a 3-D extended Marmousi-II model and a 3-D deep-water crustal-scale model illustrate how our modelling and inversion engine can efficiently extract information from ocean-bottom seismic data to simultaneously reconstruct both P- and S-wave velocities within a full waveform inversion framework.
Geophysical Journal ... arrow_drop_down Geophysical Journal InternationalArticle . 2021 . Peer-reviewedLicense: OUP Standard Publication ReuseData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess Routeshybrid 9 citations 9 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Geophysical Journal ... arrow_drop_down Geophysical Journal InternationalArticle . 2021 . Peer-reviewedLicense: OUP Standard Publication ReuseData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Other literature type , Article , Preprint 2021 France, Germany, France, FrancePublisher:Copernicus GmbH Funded by:NSF | Collaborative Research: C..., EC | CRESCENDO, NSERC +1 projectsNSF| Collaborative Research: Carbon, Water, and Energy Balance of the Arctic Landscape at Flagship Observatories in Alaska and Siberia ,EC| CRESCENDO ,NSERC ,NSF| Collaborative Research on Carbon, Water, and Energy Balance of the Arctic Landscape at Flagship Observatories in Alaska and SiberiaElodie Salmon; Fabrice Jégou; Bertrand Guenet; Line Jourdain; Chunjing Qiu; Vladislav Bastrikov; Christophe Guimbaud; Dan Zhu; Philippe Ciais; Philippe Peylin; Sébastien Gogo; Fatima Laggoun-Défarge; Mika Aurela; M. Syndonia Bret-Harte; Jiquan Chen; Bogdan H. Chojnicki; Housen Chu; C. Edgar; Eugénie S. Euskirchen; Lawrence B. Flanagan; Krzysztof Fortuniak; David Holl; Janina Klatt; Olaf Kolle; Natalia Kowalska; Lars Kutzbach; Annalea Lohila; Lutz Merbold; Włodzimierz Pawlak; Torsten Sachs; Klaudia Ziemblińska;In the global methane budget, the largest natural source is attributed to wetlands, which encompass all ecosystems composed of waterlogged or inundated ground, capable of methane production. Among them, northern peatlands that store large amounts of soil organic carbon have been functioning, since the end of the last glaciation period, as long-term sources of methane (CH4) and are one of the most significant methane sources among wetlands. To reduce uncertainty of quantifying methane flux in the global methane budget, it is of significance to understand the underlying processes for methane production and fluxes in northern peatlands. A methane model that features methane production and transport by plants, ebullition process and diffusion in soil, oxidation to CO2, and CH4 fluxes to the atmosphere has been embedded in the ORCHIDEE-PEAT land surface model that includes an explicit representation of northern peatlands. ORCHIDEE-PCH4 was calibrated and evaluated on 14 peatland sites distributed on both the Eurasian and American continents in the northern boreal and temperate regions. Data assimilation approaches were employed to optimized parameters at each site and at all sites simultaneously. Results show that methanogenesis is sensitive to temperature and substrate availability over the top 75 cm of soil depth. Methane emissions estimated using single site optimization (SSO) of model parameters are underestimated by 9 g CH4 m−2 yr−1 on average (i.e., 50 % higher than the site average of yearly methane emissions). While using the multi-site optimization (MSO), methane emissions are overestimated by 5 g CH4 m−2 yr−1 on average across all investigated sites (i.e., 37 % lower than the site average of yearly methane emissions).
Geoscientific Model ... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2021Data sources: Copernicus PublicationsGFZ German Research Centre for GeosciencesArticle . 2022License: CC BYData sources: GFZ German Research Centre for GeosciencesGeoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus Publicationshttps://doi.org/10.5194/gmd-20...Preprint . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefHAL Descartes; Mémoires en Sciences de l'Information et de la Communication; HAL-CEAArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 7 citations 7 popularity Top 10% influence Average impulse Top 10% Powered by BIP!more_vert Geoscientific Model ... arrow_drop_down Geoscientific Model Development (GMD)Other literature type . 2021Data sources: Copernicus PublicationsGFZ German Research Centre for GeosciencesArticle . 2022License: CC BYData sources: GFZ German Research Centre for GeosciencesGeoscientific Model Development (GMD)Other literature type . 2022Data sources: Copernicus Publicationshttps://doi.org/10.5194/gmd-20...Preprint . 2021 . Peer-reviewedLicense: CC BYData sources: CrossrefHAL Descartes; Mémoires en Sciences de l'Information et de la Communication; HAL-CEAArticle . 2022License: CC BYadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Preprint 2021 Italy, France, Belgium, ItalyPublisher:American Astronomical Society Funded by:ANR | e-PYTHEAS, EC | ExoAI, EC | ExoMAC +5 projectsANR| e-PYTHEAS ,EC| ExoAI ,EC| ExoMAC ,EC| ATMO ,UKRI| ARIEL SCIENCE ADVISORY TEAM UK ACTIVITIES ,UKRI| UCL Centre for Doctoral Training in Data Intensive Science and Technologies ,EC| WHIPLASH ,EC| ExoplANETS ALorenzo V. Mugnai; Darius Modirrousta-Galian; Billy Edwards; Quentin Changeat; Jeroen Bouwman; Giuseppe Morello; Ahmed Al-Refaie; Robin Baeyens; Michelle Fabienne Bieger; Doriann Blain; Amélie Gressier; Gloria Guilluy; Yassin Jaziri; Flavien Kiefer; Mario Morvan; William Pluriel; Mathilde Poveda; Nour Skaf; Niall Whiteford; Sam Wright; Kai Hou Yip; Tiziano Zingales; Benjamin Charnay; Pierre Drossart; Jérémy Leconte; Olivia Venot; Ingo Waldmann; Jean-Philippe Beaulieu;handle: 11577/3415977 , 11573/1549763
We present a study on the spatially scanned spectroscopic observations of the transit of GJ 1132 b, a warm ($\sim$500 K) Super-Earth (1.13 R$_\oplus$) that was obtained with the G141 grism (1.125 - 1.650 $\mu$m) of the Wide Field Camera 3 (WFC3) onboard the Hubble Space Telescope. We used the publicly available Iraclis pipeline to extract the planetary transmission spectra from the five visits and produce a precise transmission spectrum. We analysed the spectrum using the TauREx3 atmospheric retrieval code with which we show that the measurements do not contain molecular signatures in the investigated wavelength range and are best-fit with a flat-line model. Our results suggest that the planet does not have a clear primordial, hydrogen-dominated atmosphere. Instead, GJ 1132 b could have a cloudy hydrogen-dominated envelope, a very enriched secondary atmosphere, be airless, or have a tenuous atmosphere that has not been detected. Due to the narrow wavelength coverage of WFC3, these scenarios cannot be distinguished yet but the James Webb Space Telescope may be capable of detecting atmospheric features, although several observations may be required to provide useful constraints. Comment: 17 pages, 11 figures. Accepted for publication in AJ
Archivio della ricer... arrow_drop_down Archivio istituzionale della ricerca - Università di Padova; The Astronomical JournalOther literature type . Article . 2021 . Peer-reviewedLicense: IOP Copyright PoliciesArchivio della ricerca- Università di Roma La SapienzaArticle . 2021Data sources: Archivio della ricerca- Università di Roma La SapienzaHAL - UPEC / UPEM; Hal-DiderotArticle . 2021add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.euAccess RoutesGreen gold 38 citations 38 popularity Top 1% influence Average impulse Top 1% Powered by BIP!visibility 25visibility views 25 Powered bymore_vert Archivio della ricer... arrow_drop_down Archivio istituzionale della ricerca - Università di Padova; The Astronomical JournalOther literature type . Article . 2021 . Peer-reviewedLicense: IOP Copyright PoliciesArchivio della ricerca- Università di Roma La SapienzaArticle . 2021Data sources: Archivio della ricerca- Università di Roma La SapienzaHAL - UPEC / UPEM; Hal-DiderotArticle . 2021add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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