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  • 2013-2022
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  • Publication . Other literature type . Article . 2021
    Open Access English

    Someone who is unable or unwilling to return to their country of origin owing to a well-founded fear of being persecuted for reasons of race, religion, nationality, membership of a particular social group, or political opinion is known as Refugee. And an asylum seeker is someone whose request for sanctuary has yet to be processed. In Today's world, the rights of Rohingya refugees are very debatable. Our topic is The Educational rights of Rohingya Refugees Children in Bangladesh (an analysis). There are some social, cultural, and language barriers to providing education rights to Rohingya children and Bangladesh is not also under an obligation to do so as Bangladesh hasn’t signed the 1951 convention of refugees. So basically the research is based on how to ensure the right of Rohingya children otherwise in its absence. We also tried to understand the problems, the gaps, the Bangladesh situation, and international instruments. A big question is Bangladesh has been under the duty to secure the interest of refugee education and the explanation on that by which law and convention are labile or not for refugee children's education. Bangladesh has not signed the Refugee Convention. So that, Bangladesh is not legally bound to ensure that right and no law regulates and for the administration of refugee affairs in Bangladesh or guarantees the rights of refugees. There are a lot of Refugees in Bangladesh but because Bangladesh is not a signatory state of the 1951 convention, that's why they are known as Asylum Seekers. Though Education is a very important and basic entitlement for humans still there is some debate. Being born as human refugees are entitled to have some rights and education is one of them. But now there is a lot of debate on that ground. {"references": ["Alif Ovi D, and Mridha T, 'Education Rights Of Rohingya Refugees Children In Bangladesh: An Analysis' (2021) 2 Jus Corpus Law Journal ", "Alif Ovi, D., & Mridha, T. (2021). Education Rights of Rohingya Refugees Children in Bangladesh: An Analysis. Jus Corpus Law Journal, 2(2), 26-47. from", "Alif Ovi, D. and Mridha, T., 2021. Education Rights of Rohingya Refugees Children in Bangladesh: An Analysis. Jus Corpus Law Journal, [online] 2(2), pp.26-47. Available at: "]}

  • Open Access English
    Frank Lehrbass;
    Publisher: Zenodo

    The European Markets Infrastructure Regulation (EMIR) allows burdening a clearing obligation on non-financial corporations, which formerly did not necessarily clear their business. We give 10 recommendations on how to cope with this obligation. These are motivated by a case study for which we consider a stylized German power producer. For this entity, we derive optimal levels of planned production and forward sales of power using microeconomic theory. Since this results in a significant short position in the German power forward market, we investigate the resulting variation margin call dynamics with a special interest in the ability to forecast worst-case price up moves. We compare different models for the forward log-returns and their performance in 99% quantile forecasting. A GARCH model with Student-t distribution emerges as the most suitable model. This is used in the case study, which is inspired by data published by the power producer E.ON. Using recent material from the Basel Committee on Banking Supervision we distill the reliable liquidity buffer from an allegedly rich liquidity position and show how suddenly it can be eroded. We point to feedback loops, which make the challenges—posed by the clearing obligation—even more severe. We also spend some thoughts on how to cope with the crisis caused by Corona.

  • German
    Bala, Mehmet Murat; Bala, Keziban Aslı; Hancı, Fatma; Bayraktar, Zehra; Kabakuş, Nimet;
    Publisher: Unpublished
  • English
    Edmond, Jennifer; Basaraba, Nicole; Doran, Michelle; Garnett, Vicky; Grile, Courtney Helen; Papaki, Eliza; Tóth-Czifra, Erzsébet;
    Publisher: HAL CCSD
    Country: France
  • Open Access
    BALA, Mehmet Murat; BALA, Keziban Aslı;
    Publisher: Wroclaw Medical University

    BACKGROUND Osteogenesis imperfecta (OI) is a genetic disorder that causes skeletal fragility, multiple fractures and several extraskeletal disorders. Most cases of OI are caused by mutations in COL1A1/A2. Osteogenesis imperfecta type VIII typically causes a severe and fatal phenotype that presents at birth with severe osteopenia, congenital fractures and other clinical manifestations. OBJECTIVES We describe the cases of an 11-year-old female and a 9-year-old male with homozygous truncating mutations in P3H1. Both cases were born with intrauterine fractures and suffered multiple fractures shortly after birth, requiring multiple operations to correct both fractures and severe scoliosis. The patients have been treated with pamidronate since the age of 2. MATERIAL AND METHODS Whole exome sequencing (WES) was performed by Gene by Gene using Twist Bioscience technology. Initially, ~36.5 Mb of consensus coding sequences (targeting >98% of RefSeq and Gencode v. 28 regions obtained from the human genome) was replicated from fragmented genomic DNA using the Twist Human Core Exome Plus kit. The subsequent library was sequenced on the Illumina Novaseq Next Generation Sequencing platform to achieve at least ×20 reading depth for >98% of the targeted bases. Variant annotations and filtering was performed using Ingenuity Variant Analysis software. RESULTS We identified a homozygous mutation in the 3rd exon of P3H1 (c.628C>T/p.Arg210 Ter). Our cases broaden the phenotypic spectrum of OI type VIII as, to the best of our knowledge, these are the first postnatal cases with P3H1 (c.628C>T/p.Arg210 Ter) mutations published in the literature. CONCLUSIONS We present the first recorded postnatal cases from unrelated families of OI type VIII, broadening our understanding of the severe, but nonfatal spectrum of clinical phenotype of this recessive form of OI.

  • Open Access English
    Ovi, Dewan Alif; Reza, Tanvir;
    Publisher: Mr. Arvind Sharma

    ABSTRACT Custodial death is the most ominous indicator in our country's capture, detention, and remand. It has now become all the rage across the country. Deaths in police custody usually generate a great deal of public attention and are frequently coupled with causality disputes. Accused individuals frequently come into encounter with the criminal justice system, with those suffering from mental illnesses over-represented in police custody. As a result, identifying vulnerability is critical in order to guarantee that proper precautions may be put in place. This research is helping to show that to prevent such a curse from afflicting society, the country has some existing legislation, directions, guidelines, and precedents that are constantly derived from court decisions of other nations. The judicial system in Bangladesh is no exception. In context of this, the research examined, with the goal of emphasizing on judicial reforms, applicable legislation and their implementation, national legislative framework, and court precedents on the banning of inhumane custodial torture, including arrest, custody, and remand by police. Finding of the research particularly concentrate upon irregularities of provision to safeguarding accused right in the jail. The lack of sanitation, healthcare, standard food quality also found as errors of concern authorities. Beside these normal and natural death also counted as death in custody but not due to torture by police. The political believes and support nurture by police is also one of the key reasons to increasing torture and deaths. To solve these problems state should amend existing provision which is contradictory related to custodial torture, Increase the circumference of Human Rights Commission and give them power to investigate these properly and follow the guidelines given by courts. This research demonstrated a real-life scenario of custodial torture and critically analyzed national mechanisms that directly contradict custodial deaths and brutal punishment. {"references": ["'Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability' (2022) IV Indian Journal of Law and Legal Research", "Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability. (2022), IV(III), 1266-1287", "Indian Journal of Law and Legal Research, 2022. Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability. IV(III), pp.1266-1287", "\"Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability.\". IV, no. III, 2022, pp. 1266-1287", "\"Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability\" (2022) IV(III)", "\"Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability\". Indian Journal Of Law And Legal Research no. (2022): 1266-1287. doi:", "\"Police Custody Deaths In Bangladesh: An Analysis Of Legal Liability\", (2022) IV Indian Journal of Law and Legal Research 1266-1287."]}

  • Closed Access
    Durukan, Yasin; Bala, Mehmet Murat; Şahin, Abdullah Alper; Fırat, Tülin; Buğdaycı, Güler; Özturan, Kutay Engin;
    Publisher: Elsevier BV

    Abstract Background We aimed to compare biochemical and histopathological findings of astaxanthin's potential effects on oxidative stress in ischemia/reperfusion damage (I/R). Methods Thirty-two rats were randomly divided into four groups: control group; I/R group; I/R + treatment group; drug group. Astaxanthin was orally administered to groups C and D for 14 days. In groups B and C, the femoral artery was clamped for 2 h to form ischemia. The clamp was opened, and reperfusion was performed for 1 h. In all groups, 4 ml of blood sample through intracardiac puncture and gastrocnemius muscle tissue samples were collected. Serum and tissue samples were analyzed by measuring malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (TAC), and total oxidative level (TOL). Necrosis, inflammation, and caspase-3 in muscle tissue collected for histopathological examination were evaluated. Results Tissue MDA, SOD and TOL values significantly differed between groups. Serum MDA, SOD, TOL and TAC values significantly differed between groups. On necrosis examination, there was a significant difference between groups B and C. Although signs of inflammation significantly differed between groups, there was no significant difference between groups A and C and groups A and D. Although there was a significant difference in caspase-3 results between groups, there was no significant difference between groups A and C. Conclusions The use of astaxanthin before and after surgery showed preventive or therapeutic effects against I/R damage.

  • Open Access English
    Mehmet Akif Boz; Husamettin Cakici; M. Pakdil; Abdullah Alper Şahin; Selma Erdogan Duzcu; Mehmet Murat Bala; Metin Celik;
    Publisher: Turkish Joint Diseases Foundation
    Country: Turkey

    WOS:000545984600012 PubMed: 32584721 Objectives: This study aims to biomechanically and histopathologically investigate the effects of methylene blue (MB) on preventing postoperative adhesion in chickens undergoing full - thickness flexor tendon incision. Materials and methods: This study was performed between June 2017 and June 2018 on Hubbard JA 57 type chickens (age, 6 months; weight, 2.2?0.3 kg). Sixty-four tendons were studied in 32 chickens, including 16 in the control group and 16 in the experimental group. The second and third finger flexor digitorum profundus tendons of the left foot of each chicken were repaired primarily after a full -thickness incision approximately 1 cm proximal to the distal adhesion area. In the control (n=32) and experimental groups (n=32), 0.25 mL of normal saline and 0.25 mL of 1% MB solutions were applied locally to the surgical site, respectively. The operated limb was immobilized using a circular cast. 16 chickens were randomly selected in each group and examined at the fourth week, and the remaining 16 chickens were examined at the sixth week. Thirty-two of these tendons were evaluated using the Tang histopathological adhesion classification system, and the other 32 were evaluated with a biomechanical pull system. Results: Adhesion was found to be less in the experimental group compared to the control group at the end of the fourth and sixth weeks both histopathologically and biomechanically. Furthermore, adhesion was significantly less in the experimental group at the end of the sixth week compared to the fourth week both histopathologically and biomechanically. Conclusion: Histopathological and biomechanical results show that MB, which has anti-inflammatory, antiseptic, antimicrobial and antioxidant effects, reduces adhesion during the healing process after tendon repair. We think that local MB application, particularly in surgeries performed after this type of injury, will be beneficial on early rehabilitation and functional results.

  • Open Access
    Mehmet Murat Bala; Abdullah Alper Şahin; Mehmet Akif Boz; Yasin Durukan; Tulin Firat; M. Pakdil; Kutay Engin Ozturan;
    Publisher: International Scientific Information, Inc.

    BACKGROUND In this study, we aimed to investigate the effects of N-butyl-2-cyanoacrylate (cyanoacrylate) on the biomechanical and histopathological aspects of tendon healing in a rabbit model of Achilles tendon injury. MATERIAL AND METHODS In total, 36 rabbits were randomized to experimental (cyanoacrylate) and control groups (n=36 tendons in each group). A simple suture was used in the control group and a simple suture plus cyanoacrylate was used in the experimental group. Nine rabbits from each group were euthanized at week 4 and week 6 after surgery for histopathological and biomechanical testing. RESULTS Granulation tissue formation was significantly greater in the experimental group in week 4 and week 6 than in the control group. Foreign body giant cell formation was significantly higher in the experimental group in week 4 and week 6. The maximum rupture force was significantly higher in the experimental group in week 4 and week 6 than in the control group. Elasticity and stiffness were comparable between groups in week 4; however, stiffness, but not elasticity, was significantly higher in the experimental group in week 6. CONCLUSIONS In the short term, cyanoacrylate enhanced tendon endurance in both a histopathological and biomechanical manner. We conclude that the early initiation of rehabilitation in patients may be safe in cases of cyanoacrylate use for surgical repair of tendon injury.