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9 Research products, page 1 of 1

  • DARIAH EU
  • Publications
  • Research data
  • 2018-2022
  • Open Access
  • DARIAH EU
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  • Open Access
    Authors: 
    Olusoji Akinola;
    Publisher: Elsevier BV

    This paper centers on assessing the socio-economic impact of electronic banking business in Sub-Saharan Africa, while critically observing the role that emerging FinTech ecosystems play in deepening economic inclusion and access in developing countries. Extensive related literatures were consulted which were integrated into this new body of knowledge, which has been one of the recommended areas for future research. Research hypothesis were derived to validate relevant findings. This study aim to provide transparency on whether the development of digital payments business and FinTech ecosystems are having a synergistic positive impact or otherwise, on the economic well-being of developing countries. It will also support potential foreign investors and multilateral development agencies on relevant socio-economic factors to note, while expanding into or supporting development in developing countries. The implication of this is for policyholders, multilateral development organizations, investors, donor agencies and governments to be conscious of the real impact and take perceptual measures where and when the need arises.

  • Open Access
    Authors: 
    Georgios Artopoulos; Gloria Pignatta; Mattheos Santamouris;
    Publisher: UCL Press

    Almost a century ago Modernism challenged the structure of the city and reshaped its physical space in order to, amongst other things, accommodate new transportation infrastructure and road networks proclaiming the, nowadays much-debated ‘scientificated’ pursuit of efficiency for the city. This transformation has had a great impact on the way humans still design, move in, occupy and experience the city. Today major cities in Europe, such as Paris and London, are considering banning vehicles from their historic centers. In parallel, significant effort is currently underway internationally by designers, architects, and engineers to integrate innovative technologies and sophisticated solutions for energy production, management, and storage, as well as for efficient energy consumption, into the architecture of buildings. In general, this effort seeks for new technologies and design methods (e.g., DesignBuilder with EnergyPlus simulation engine; Rhicoceros3D with Grasshopper plugin and Ecotect, Radiance and EnergyPlus tools) that would enable a holistic approach to the spatial design of Near-Zero Energy buildings, so that their ecological benefits are an added value to the architectural design and a building’s visual, and material, impact on its surrounding space. The paper inquires how the integration of such technological infrastructure and performance-orientated interfaces changes yet again the structure and form of cities, and to what extent it safeguards social rights and enables equal access to common resources. Drawing from preliminary results and initial considerations of ongoing research that involve the construction of four innovative NZE settlements across Europe, in the context of the EU-funded ZERO-PLUS project, this paper discusses the integration of novel infrastructure in communal spaces of these settlements. In doing so, it contributes to the debate about smart communities and their role in the sustainable management of housing developments and settlements that are designed and developed with the concept of smart territories.

  • Open Access Arabic
    Authors: 
    Ali Saeed Hammoodi Al-Chalabi; Rana A. Asim; Hasliza A. Rahim; Mohamed Fareq Abdul Malek;
    Publisher: University of Mosul, College of Veterinary Medicine

    Exposure to LTE 2600 MHz microwaves is increasing very fast as new technologies and become accessible worldwide, and the smartphones being the main source of these waves. The aim of this study is to assess the thermal effect of 4G signals on rats. Forty adult Albino rats were used throughout the study, assigned as control and exposed groups, equally. Rats were kept in Plexiglas cages with intermittent exposure to LTE mobile-phone like signals at an average of 2h/day for up to 30 continuous days with SAR value of 0.982 W/kg. Infrared images were snapped immediately after the end of the exposure time, then one hour, two hours, and four hours later at a rate one collection/week during the study. IR images were analyzed by FLIR Tools software. The results exhibited variation in reflected skin temperatures in the exposed group compared to control images. Furthermore, the analysis of collected data revealed significant variations over the course of the study compared to the first week. The rise in skin temperature observed in response to exposure in the first week, which decreased gradually increased exposure and this drop in reflected skin temperature was significantly related to amount of exposure. The study concludes that the LTE 2600 MHz exposure under controlled laboratory conditions has a thermal effect on the rats.

  • Open Access
    Authors: 
    Mehmet Murat BALA; Keziban Aslı BALA;
    Publisher: Wroclaw Medical University

    BACKGROUND Osteogenesis imperfecta (OI) is a genetic disorder that causes skeletal fragility, multiple fractures and several extraskeletal disorders. Most cases of OI are caused by mutations in COL1A1/A2. Osteogenesis imperfecta type VIII typically causes a severe and fatal phenotype that presents at birth with severe osteopenia, congenital fractures and other clinical manifestations. OBJECTIVES We describe the cases of an 11-year-old female and a 9-year-old male with homozygous truncating mutations in P3H1. Both cases were born with intrauterine fractures and suffered multiple fractures shortly after birth, requiring multiple operations to correct both fractures and severe scoliosis. The patients have been treated with pamidronate since the age of 2. MATERIAL AND METHODS Whole exome sequencing (WES) was performed by Gene by Gene using Twist Bioscience technology. Initially, ~36.5 Mb of consensus coding sequences (targeting >98% of RefSeq and Gencode v. 28 regions obtained from the human genome) was replicated from fragmented genomic DNA using the Twist Human Core Exome Plus kit. The subsequent library was sequenced on the Illumina Novaseq Next Generation Sequencing platform to achieve at least ×20 reading depth for >98% of the targeted bases. Variant annotations and filtering was performed using Ingenuity Variant Analysis software. RESULTS We identified a homozygous mutation in the 3rd exon of P3H1 (c.628C>T/p.Arg210 Ter). Our cases broaden the phenotypic spectrum of OI type VIII as, to the best of our knowledge, these are the first postnatal cases with P3H1 (c.628C>T/p.Arg210 Ter) mutations published in the literature. CONCLUSIONS We present the first recorded postnatal cases from unrelated families of OI type VIII, broadening our understanding of the severe, but nonfatal spectrum of clinical phenotype of this recessive form of OI.

  • Publication . Conference object . Article . 2018
    Open Access
    Authors: 
    Elisabeth Heinemann;
    Publisher: OpenEdition Press

    International audience; This paper develops the concept of network sustainability. To become and stay sustainable, distributed research infrastructures must satisfy present needs while at the same time be flexible and resilient to meet future requirements. For this it is not enough to merely build a resilient economic model and be technically viable. Research infrastructures that can understand, address and shape future needs have a sustainable community network. Clear characteristics of a research infrastructure with a sustainable network are that partners gain access to other networks and interest groups, that knowledge, information and expertise is shared freely among partners, that the infrastructure increases partners’ visibilities and vice versa, and that partners are enabled to stay current and state-of-the-art. This is shown on OPERAS (open access in the european research area through scholarly communication), a research infrastructure for open scholarly communication in the social sciences and humanities, and its partner the Max Weber Foundation, a German research institution.

  • Open Access English
    Authors: 
    Mehmet Akif Boz; Husamettin Cakici; M. Pakdil; Abdullah Alper Şahin; Selma Erdogan Duzcu; Mehmet Murat Bala; Metin Celik;
    Publisher: Turkish Joint Diseases Foundation
    Country: Turkey

    WOS:000545984600012 PubMed: 32584721 Objectives: This study aims to biomechanically and histopathologically investigate the effects of methylene blue (MB) on preventing postoperative adhesion in chickens undergoing full - thickness flexor tendon incision. Materials and methods: This study was performed between June 2017 and June 2018 on Hubbard JA 57 type chickens (age, 6 months; weight, 2.2?0.3 kg). Sixty-four tendons were studied in 32 chickens, including 16 in the control group and 16 in the experimental group. The second and third finger flexor digitorum profundus tendons of the left foot of each chicken were repaired primarily after a full -thickness incision approximately 1 cm proximal to the distal adhesion area. In the control (n=32) and experimental groups (n=32), 0.25 mL of normal saline and 0.25 mL of 1% MB solutions were applied locally to the surgical site, respectively. The operated limb was immobilized using a circular cast. 16 chickens were randomly selected in each group and examined at the fourth week, and the remaining 16 chickens were examined at the sixth week. Thirty-two of these tendons were evaluated using the Tang histopathological adhesion classification system, and the other 32 were evaluated with a biomechanical pull system. Results: Adhesion was found to be less in the experimental group compared to the control group at the end of the fourth and sixth weeks both histopathologically and biomechanically. Furthermore, adhesion was significantly less in the experimental group at the end of the sixth week compared to the fourth week both histopathologically and biomechanically. Conclusion: Histopathological and biomechanical results show that MB, which has anti-inflammatory, antiseptic, antimicrobial and antioxidant effects, reduces adhesion during the healing process after tendon repair. We think that local MB application, particularly in surgeries performed after this type of injury, will be beneficial on early rehabilitation and functional results.

  • Open Access
    Authors: 
    Mehmet Murat Bala; Abdullah Alper Şahin; Mehmet Akif Boz; Yasin Durukan; Tulin Firat; M. Pakdil; Kutay Engin Ozturan;
    Publisher: International Scientific Information, Inc.

    BACKGROUND In this study, we aimed to investigate the effects of N-butyl-2-cyanoacrylate (cyanoacrylate) on the biomechanical and histopathological aspects of tendon healing in a rabbit model of Achilles tendon injury. MATERIAL AND METHODS In total, 36 rabbits were randomized to experimental (cyanoacrylate) and control groups (n=36 tendons in each group). A simple suture was used in the control group and a simple suture plus cyanoacrylate was used in the experimental group. Nine rabbits from each group were euthanized at week 4 and week 6 after surgery for histopathological and biomechanical testing. RESULTS Granulation tissue formation was significantly greater in the experimental group in week 4 and week 6 than in the control group. Foreign body giant cell formation was significantly higher in the experimental group in week 4 and week 6. The maximum rupture force was significantly higher in the experimental group in week 4 and week 6 than in the control group. Elasticity and stiffness were comparable between groups in week 4; however, stiffness, but not elasticity, was significantly higher in the experimental group in week 6. CONCLUSIONS In the short term, cyanoacrylate enhanced tendon endurance in both a histopathological and biomechanical manner. We conclude that the early initiation of rehabilitation in patients may be safe in cases of cyanoacrylate use for surgical repair of tendon injury.

  • Publication . Other literature type . Conference object . Article . 2018
    Open Access English
    Authors: 
    Nathalie Fargier;
    Publisher: HAL CCSD
    Country: France

    International audience; A wide range of initiatives for developing research and data infrastructures have been funded in recent years. There is a growing concern amongst the academic community to maintain the resources invested beyond the period of the original research funding. If technical progress has been made to preserve the data themselves, few thinking and operational solutions exist for the institutions that create, disseminate, curate and preserve the data. How to ensure their existence over the medium or the long-term? This paper is a case study: it addresses the sustainability issues faced by Persée, a French platform dedicated to digitized documentary heritage that was launched in 2003. Through this example, the aim is to present, in practical terms, how an organization has to adapt and to change to sustain over time. Persée tested and combined various mechanisms (technical actions, users’ involvement, organizational evolution, marketing, funding models) with reciprocal influence, to achieve sustainability. Rather than a steady state, ensuring the long term existence of a data infrastructure is an ongoing and resource intensive process.

  • Open Access
    Authors: 
    Jennifer Edmond; Francesca Morselli;
    Publisher: Emerald
    Country: Netherlands

    PurposeThis paper proposes a new perspective on the enormous and unresolved challenge to existing practices of publication and documentation posed by the outputs of digital research projects in the humanities, where much good work is being lost due to resource or technical challenges.Design/methodology/approachThe paper documents and analyses both the existing literature on promoting sustainability for the outputs of digital humanities projects and the innovative approach of a single large-scale project.FindingsThe findings of the research presented show that sustainability planning for large-scale research projects needs to consider data and technology but also community, communications and process knowledge simultaneously. In addition, it should focus not only on a project as a collection of tangible and intangible assets, but also on the potential user base for these assets and what these users consider valuable about them.Research limitations/implicationsThe conclusions of the paper have been formulated in the context of one specific project. As such, it may amplify the specificities of this project in its results.Practical implicationsAn approach to project sustainability following the recommendations outlined in this paper would include a number of uncommon features, such as a longer development horizon, wider perspective on project results, and an audit of tacit and explicit knowledge.Social ImplicationsThese results can ultimately preserve public investment in projects.Originality/valueThis paper supplements more reductive models for project sustainability with a more holistic approach that others may learn from in mapping and sustaining user value for their projects for the medium to long terms.

Advanced search in Research products
Research products
arrow_drop_down
Searching FieldsTerms
Any field
arrow_drop_down
includes
arrow_drop_down
Include:
The following results are related to DARIAH EU. Are you interested to view more results? Visit OpenAIRE - Explore.
9 Research products, page 1 of 1
  • Open Access
    Authors: 
    Olusoji Akinola;
    Publisher: Elsevier BV

    This paper centers on assessing the socio-economic impact of electronic banking business in Sub-Saharan Africa, while critically observing the role that emerging FinTech ecosystems play in deepening economic inclusion and access in developing countries. Extensive related literatures were consulted which were integrated into this new body of knowledge, which has been one of the recommended areas for future research. Research hypothesis were derived to validate relevant findings. This study aim to provide transparency on whether the development of digital payments business and FinTech ecosystems are having a synergistic positive impact or otherwise, on the economic well-being of developing countries. It will also support potential foreign investors and multilateral development agencies on relevant socio-economic factors to note, while expanding into or supporting development in developing countries. The implication of this is for policyholders, multilateral development organizations, investors, donor agencies and governments to be conscious of the real impact and take perceptual measures where and when the need arises.

  • Open Access
    Authors: 
    Georgios Artopoulos; Gloria Pignatta; Mattheos Santamouris;
    Publisher: UCL Press

    Almost a century ago Modernism challenged the structure of the city and reshaped its physical space in order to, amongst other things, accommodate new transportation infrastructure and road networks proclaiming the, nowadays much-debated ‘scientificated’ pursuit of efficiency for the city. This transformation has had a great impact on the way humans still design, move in, occupy and experience the city. Today major cities in Europe, such as Paris and London, are considering banning vehicles from their historic centers. In parallel, significant effort is currently underway internationally by designers, architects, and engineers to integrate innovative technologies and sophisticated solutions for energy production, management, and storage, as well as for efficient energy consumption, into the architecture of buildings. In general, this effort seeks for new technologies and design methods (e.g., DesignBuilder with EnergyPlus simulation engine; Rhicoceros3D with Grasshopper plugin and Ecotect, Radiance and EnergyPlus tools) that would enable a holistic approach to the spatial design of Near-Zero Energy buildings, so that their ecological benefits are an added value to the architectural design and a building’s visual, and material, impact on its surrounding space. The paper inquires how the integration of such technological infrastructure and performance-orientated interfaces changes yet again the structure and form of cities, and to what extent it safeguards social rights and enables equal access to common resources. Drawing from preliminary results and initial considerations of ongoing research that involve the construction of four innovative NZE settlements across Europe, in the context of the EU-funded ZERO-PLUS project, this paper discusses the integration of novel infrastructure in communal spaces of these settlements. In doing so, it contributes to the debate about smart communities and their role in the sustainable management of housing developments and settlements that are designed and developed with the concept of smart territories.

  • Open Access Arabic
    Authors: 
    Ali Saeed Hammoodi Al-Chalabi; Rana A. Asim; Hasliza A. Rahim; Mohamed Fareq Abdul Malek;
    Publisher: University of Mosul, College of Veterinary Medicine

    Exposure to LTE 2600 MHz microwaves is increasing very fast as new technologies and become accessible worldwide, and the smartphones being the main source of these waves. The aim of this study is to assess the thermal effect of 4G signals on rats. Forty adult Albino rats were used throughout the study, assigned as control and exposed groups, equally. Rats were kept in Plexiglas cages with intermittent exposure to LTE mobile-phone like signals at an average of 2h/day for up to 30 continuous days with SAR value of 0.982 W/kg. Infrared images were snapped immediately after the end of the exposure time, then one hour, two hours, and four hours later at a rate one collection/week during the study. IR images were analyzed by FLIR Tools software. The results exhibited variation in reflected skin temperatures in the exposed group compared to control images. Furthermore, the analysis of collected data revealed significant variations over the course of the study compared to the first week. The rise in skin temperature observed in response to exposure in the first week, which decreased gradually increased exposure and this drop in reflected skin temperature was significantly related to amount of exposure. The study concludes that the LTE 2600 MHz exposure under controlled laboratory conditions has a thermal effect on the rats.

  • Open Access
    Authors: 
    Mehmet Murat BALA; Keziban Aslı BALA;
    Publisher: Wroclaw Medical University

    BACKGROUND Osteogenesis imperfecta (OI) is a genetic disorder that causes skeletal fragility, multiple fractures and several extraskeletal disorders. Most cases of OI are caused by mutations in COL1A1/A2. Osteogenesis imperfecta type VIII typically causes a severe and fatal phenotype that presents at birth with severe osteopenia, congenital fractures and other clinical manifestations. OBJECTIVES We describe the cases of an 11-year-old female and a 9-year-old male with homozygous truncating mutations in P3H1. Both cases were born with intrauterine fractures and suffered multiple fractures shortly after birth, requiring multiple operations to correct both fractures and severe scoliosis. The patients have been treated with pamidronate since the age of 2. MATERIAL AND METHODS Whole exome sequencing (WES) was performed by Gene by Gene using Twist Bioscience technology. Initially, ~36.5 Mb of consensus coding sequences (targeting >98% of RefSeq and Gencode v. 28 regions obtained from the human genome) was replicated from fragmented genomic DNA using the Twist Human Core Exome Plus kit. The subsequent library was sequenced on the Illumina Novaseq Next Generation Sequencing platform to achieve at least ×20 reading depth for >98% of the targeted bases. Variant annotations and filtering was performed using Ingenuity Variant Analysis software. RESULTS We identified a homozygous mutation in the 3rd exon of P3H1 (c.628C>T/p.Arg210 Ter). Our cases broaden the phenotypic spectrum of OI type VIII as, to the best of our knowledge, these are the first postnatal cases with P3H1 (c.628C>T/p.Arg210 Ter) mutations published in the literature. CONCLUSIONS We present the first recorded postnatal cases from unrelated families of OI type VIII, broadening our understanding of the severe, but nonfatal spectrum of clinical phenotype of this recessive form of OI.

  • Publication . Conference object . Article . 2018
    Open Access
    Authors: 
    Elisabeth Heinemann;
    Publisher: OpenEdition Press

    International audience; This paper develops the concept of network sustainability. To become and stay sustainable, distributed research infrastructures must satisfy present needs while at the same time be flexible and resilient to meet future requirements. For this it is not enough to merely build a resilient economic model and be technically viable. Research infrastructures that can understand, address and shape future needs have a sustainable community network. Clear characteristics of a research infrastructure with a sustainable network are that partners gain access to other networks and interest groups, that knowledge, information and expertise is shared freely among partners, that the infrastructure increases partners’ visibilities and vice versa, and that partners are enabled to stay current and state-of-the-art. This is shown on OPERAS (open access in the european research area through scholarly communication), a research infrastructure for open scholarly communication in the social sciences and humanities, and its partner the Max Weber Foundation, a German research institution.

  • Open Access English
    Authors: 
    Mehmet Akif Boz; Husamettin Cakici; M. Pakdil; Abdullah Alper Şahin; Selma Erdogan Duzcu; Mehmet Murat Bala; Metin Celik;
    Publisher: Turkish Joint Diseases Foundation
    Country: Turkey

    WOS:000545984600012 PubMed: 32584721 Objectives: This study aims to biomechanically and histopathologically investigate the effects of methylene blue (MB) on preventing postoperative adhesion in chickens undergoing full - thickness flexor tendon incision. Materials and methods: This study was performed between June 2017 and June 2018 on Hubbard JA 57 type chickens (age, 6 months; weight, 2.2?0.3 kg). Sixty-four tendons were studied in 32 chickens, including 16 in the control group and 16 in the experimental group. The second and third finger flexor digitorum profundus tendons of the left foot of each chicken were repaired primarily after a full -thickness incision approximately 1 cm proximal to the distal adhesion area. In the control (n=32) and experimental groups (n=32), 0.25 mL of normal saline and 0.25 mL of 1% MB solutions were applied locally to the surgical site, respectively. The operated limb was immobilized using a circular cast. 16 chickens were randomly selected in each group and examined at the fourth week, and the remaining 16 chickens were examined at the sixth week. Thirty-two of these tendons were evaluated using the Tang histopathological adhesion classification system, and the other 32 were evaluated with a biomechanical pull system. Results: Adhesion was found to be less in the experimental group compared to the control group at the end of the fourth and sixth weeks both histopathologically and biomechanically. Furthermore, adhesion was significantly less in the experimental group at the end of the sixth week compared to the fourth week both histopathologically and biomechanically. Conclusion: Histopathological and biomechanical results show that MB, which has anti-inflammatory, antiseptic, antimicrobial and antioxidant effects, reduces adhesion during the healing process after tendon repair. We think that local MB application, particularly in surgeries performed after this type of injury, will be beneficial on early rehabilitation and functional results.

  • Open Access
    Authors: 
    Mehmet Murat Bala; Abdullah Alper Şahin; Mehmet Akif Boz; Yasin Durukan; Tulin Firat; M. Pakdil; Kutay Engin Ozturan;
    Publisher: International Scientific Information, Inc.

    BACKGROUND In this study, we aimed to investigate the effects of N-butyl-2-cyanoacrylate (cyanoacrylate) on the biomechanical and histopathological aspects of tendon healing in a rabbit model of Achilles tendon injury. MATERIAL AND METHODS In total, 36 rabbits were randomized to experimental (cyanoacrylate) and control groups (n=36 tendons in each group). A simple suture was used in the control group and a simple suture plus cyanoacrylate was used in the experimental group. Nine rabbits from each group were euthanized at week 4 and week 6 after surgery for histopathological and biomechanical testing. RESULTS Granulation tissue formation was significantly greater in the experimental group in week 4 and week 6 than in the control group. Foreign body giant cell formation was significantly higher in the experimental group in week 4 and week 6. The maximum rupture force was significantly higher in the experimental group in week 4 and week 6 than in the control group. Elasticity and stiffness were comparable between groups in week 4; however, stiffness, but not elasticity, was significantly higher in the experimental group in week 6. CONCLUSIONS In the short term, cyanoacrylate enhanced tendon endurance in both a histopathological and biomechanical manner. We conclude that the early initiation of rehabilitation in patients may be safe in cases of cyanoacrylate use for surgical repair of tendon injury.

  • Publication . Other literature type . Conference object . Article . 2018
    Open Access English
    Authors: 
    Nathalie Fargier;
    Publisher: HAL CCSD
    Country: France

    International audience; A wide range of initiatives for developing research and data infrastructures have been funded in recent years. There is a growing concern amongst the academic community to maintain the resources invested beyond the period of the original research funding. If technical progress has been made to preserve the data themselves, few thinking and operational solutions exist for the institutions that create, disseminate, curate and preserve the data. How to ensure their existence over the medium or the long-term? This paper is a case study: it addresses the sustainability issues faced by Persée, a French platform dedicated to digitized documentary heritage that was launched in 2003. Through this example, the aim is to present, in practical terms, how an organization has to adapt and to change to sustain over time. Persée tested and combined various mechanisms (technical actions, users’ involvement, organizational evolution, marketing, funding models) with reciprocal influence, to achieve sustainability. Rather than a steady state, ensuring the long term existence of a data infrastructure is an ongoing and resource intensive process.

  • Open Access
    Authors: 
    Jennifer Edmond; Francesca Morselli;
    Publisher: Emerald
    Country: Netherlands

    PurposeThis paper proposes a new perspective on the enormous and unresolved challenge to existing practices of publication and documentation posed by the outputs of digital research projects in the humanities, where much good work is being lost due to resource or technical challenges.Design/methodology/approachThe paper documents and analyses both the existing literature on promoting sustainability for the outputs of digital humanities projects and the innovative approach of a single large-scale project.FindingsThe findings of the research presented show that sustainability planning for large-scale research projects needs to consider data and technology but also community, communications and process knowledge simultaneously. In addition, it should focus not only on a project as a collection of tangible and intangible assets, but also on the potential user base for these assets and what these users consider valuable about them.Research limitations/implicationsThe conclusions of the paper have been formulated in the context of one specific project. As such, it may amplify the specificities of this project in its results.Practical implicationsAn approach to project sustainability following the recommendations outlined in this paper would include a number of uncommon features, such as a longer development horizon, wider perspective on project results, and an audit of tacit and explicit knowledge.Social ImplicationsThese results can ultimately preserve public investment in projects.Originality/valueThis paper supplements more reductive models for project sustainability with a more holistic approach that others may learn from in mapping and sustaining user value for their projects for the medium to long terms.