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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Brigita Dalecka; Martins Strods; Talis Juhna; Gunaratna Kuttuva Rajarao;

    Discharge of organic load from treated wastewater may cause environmental eutrophication. Recently, fungi have gained much attention due to their removal of pharmaceutical substances by enzymatic degradation and adsorption. However, the fungal effect in removing nutrients is less investigated. Therefore, two fungal species, the white-rot fungus T. versicolor as a laboratory strain and the mold A. luchuensis as an environmental isolate from the municipal wastewater treatment plant, were studied to determine the fungal potential for phosphorus, nitrogen, and the total organic carbon removal from municipal wastewater, carrying out a batch scale experiment to a fluidized bed pelleted bioreactor. During the batch scale experiment, the total removal (99.9 %) of phosphorus by T. versicolor was attained after a 6 hours-long incubation period while the maximal removal efficiency (99.9 %) for phosphorus from A. luchuensis was gained after an incubation period of 24 hours. Furthermore, both fungi showed that the pH adjustment to 5.5 kept the concentration of nitrogen constant and stabilized the total organic carbon reduction process for the entire incubation period. The results from the fluidized bed bioreactor demonstrated opposite tendencies on a nutrient removal comparing to a batch experiment where no significant effect on phosphorus, nitrogen, and total organics carbon reduction was observed. The obtained results from this study of batch and fluidized bed bioreactor experiments are a promising starting point for a successful fungal treatment optimization and application to wastewater treatment. QC 20210107

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Microbiological Rese...arrow_drop_down
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    Microbiological Research
    Article . 2020 . Peer-reviewed
    License: Elsevier Non-Commercial
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Microbiological Rese...arrow_drop_down
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      Microbiological Research
      Article . 2020 . Peer-reviewed
      License: Elsevier Non-Commercial
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    Authors: Lin She; Niannian Xu; Pengfei Wang; Jiquan Zhang; +8 Authors

    This letter reports the fabrication of fiber Bragg gratings (FBGs) within in-house fabricated fluoroaluminate (AlF3) glass fibers using femtosecond (fs) laser inscription at 800 nm. The grating strength of the FBGs was investigated for different pulse energies and different orders, and a 3rd-order FBG with Bragg wavelength at 1557 nm was found to have the highest reflectivity of 99.5%. In addition, the reflectivity of the mid-IR grating peaks for different orders was also studied, and a 2nd-order FBG with a reflectivity of 98.8% was obtained at 2864 nm. Finally, the temperature characteristics of a mid-IR FBG were studied between 30 °C and 150 °C, showing a linear wavelength dependence and an excellent stability for the refractive index modulation. Such highly reflectivity FBGs in AlF3 fiber have significant potential for applications in the development of compact all-fiber mid-IR fiber lasers.

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    Arrow@TU Dublin
    Article . 2022
    Data sources: Arrow@TU Dublin
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    https://doi.org/10.1109/jphot....
    Article . 2022 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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    Article . 2022
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      Arrow@TU Dublin
      Article . 2022
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      https://doi.org/10.1109/jphot....
      Article . 2022 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
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      Article . 2022
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Rio, Maud; Reyes, Tatiana; Roucoules, Lionel;

    Lien vers la version éditeur: http://annals.fih.upt.ro/pdf-full/2011/ANNALS-2011-1-17.pdf; International audience; Integrating environmental aspects in the design process is getting more and more covered by the actual scientific research. Based on various fields such as "eco-design", "Design for sustainability", "eco-innovation", several specific software and methods have been developed to tackle this issue. Our work focuses on product designer software and eco-designer software that already exist. This research analyses product design and eco-design--considering their respective complexity--in order to determine the main difficulties to systematically integrate environmental aspects in the design process. Our observations have led us to work on three elements: information, software, and collaboration between designers and LCA expert. The principal objective is to facilitate the interface between product design and eco-design by linking the requirements and performances of both domains. It seems therefore necessary to help the collaboration between various experts and thus to develop a digital interface enabling designers to exchange data and to use their appropriate related software. The aim of this paper is to argue the need of a digital tool interfacing the actual tools of the design process and of eco-design (among the related software such as CAD, CAx, PLM, and LCA). This "digital interface" is presented at the end of the paper and will be created next year.

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    Authors: Blancher, Philippe; Lefrançois, Estelle; Rimet, Frédéric; Vasselon, Valentin; +53 Authors

    Recent advances in molecular biomonitoring open new horizons for aquatic ecosystem assessment. Rapid and cost-effective methods based on organismal DNA or environmental DNA (eDNA) now offer the opportunity to produce inventories of indicator taxa that can subsequently be used to assess biodiversity and ecological quality. However, the integration of these new DNA-based methods into current monitoring practices is not straightforward, and will require coordinated actions in the coming years at national and international levels. To plan and stimulate such an integration, the European network DNAqua-Net (COST Action CA15219) brought together international experts from academia, as well as key environmental biomonitoring stakeholders from different European countries. Together, this transdisciplinary consortium developed a roadmap for implementing DNA-based methods with a focus on inland waters assessed by the EU Water Framework Directive (2000/60/EC). This was done through a series of online workshops held in April 2020, which included fifty participants, followed by extensive synthesis work. The roadmap is organised around six objectives: 1) to highlight the effectiveness and benefits of DNA-based methods, 2) develop an adaptive approach for the implementation of new methods, 3) provide guidelines and standards for best practice, 4) engage stakeholders and ensure effective knowledge transfer, 5) support the environmental biomonitoring sector to achieve the required changes, 6) steer the process and harmonise efforts at the European level. This paper provides an overview of the forum discussions and the common European views that have emerged from them, while reflecting the diversity of situations in different countries. It highlights important actions required for a successful implementation of DNA-based biomonitoring of aquatic ecosystems by 2030.

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    Ktisis
    Article . 2022
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    Metabarcoding and Metagenomics; ZENODO
    Article . 2022 . Peer-reviewed
    License: CC BY
    Data sources: ZENODO; Crossref
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    DOAJ
    Article . 2022
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Ktisisarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      Article . 2022
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      Metabarcoding and Metagenomics; ZENODO
      Article . 2022 . Peer-reviewed
      License: CC BY
      Data sources: ZENODO; Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Ekaterini Lambrinou; Tiny Jaarsma; Ewa Piotrowicz; Petar M. Seferović; +2 Authors

    Although exercise training has been found to be beneficial for the physical capacity and exercise tolerance in heart failure (HF) patients,1 and even though exercise training is recommended as a class I non-pharmacological treatment,2 only a few patients adhere to exercise training or some fail to exercise at all.1 In a recent survey performed by the Heart Failure Association of the European Society of Cardiology in collaboration with the HF National Societies the diversity in management of HF patients in Europe was described.3 In the survey it was also noted that 25 of the 33 responding countries reported that they have HF clinics in their country and it is known that only a limited number of them include an exercise component in HF rehabilitation programmes.4.

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    Ktisis
    Article . 2014
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    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    European Journal of Cardiovascular Nursing
    Article . 2014 . Peer-reviewed
    License: SAGE TDM
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      Article . 2014
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      European Journal of Cardiovascular Nursing
      Article . 2014 . Peer-reviewed
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    Authors: Nicholas J Kassebaum; Amelia Bertozzi-Villa; Megan Coggeshall; Katya Anne Shackelford; +253 Authors

    BACKGROUND: The fifth Millennium Development Goal (MDG 5) established the goal of a 75% reduction in the maternal mortality ratio (MMR; number of maternal deaths per 100,000 livebirths) between 1990 and 2015. We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with respect to delivery.METHODS: We used robust statistical methods including the Cause of Death Ensemble model (CODEm) to analyse a database of data for 7065 site-years and estimate the number of maternal deaths from all causes in 188 countries between 1990 and 2013. We estimated the number of pregnancy-related deaths caused by HIV on the basis of a systematic review of the relative risk of dying during pregnancy for HIV-positive women compared with HIV-negative women. We also estimated the fraction of these deaths aggravated by pregnancy on the basis of a systematic review. To estimate the numbers of maternal deaths due to nine different causes, we identified 61 sources from a systematic review and 943 site-years of vital registration data. We also did a systematic review of reports about the timing of maternal death, identifying 142 sources to use in our analysis. We developed estimates for each country for 1990-2013 using Bayesian meta-regression. We estimated 95% uncertainty intervals (UIs) for all values.FINDINGS: 292,982 (95% UI 261,017-327,792) maternal deaths occurred in 2013, compared with 376,034 (343,483-407,574) in 1990. The global annual rate of change in the MMR was -0·3% (-1·1 to 0·6) from 1990 to 2003, and -2·7% (-3·9 to -1·5) from 2003 to 2013, with evidence of continued acceleration. MMRs reduced consistently in south, east, and southeast Asia between 1990 and 2013, but maternal deaths increased in much of sub-Saharan Africa during the 1990s. 2070 (1290-2866) maternal deaths were related to HIV in 2013, 0·4% (0·2-0·6) of the global total. MMR was highest in the oldest age groups in both 1990 and 2013. In 2013, most deaths occurred intrapartum or postpartum. Causes varied by region and between 1990 and 2013. We recorded substantial variation in the MMR by country in 2013, from 956·8 (685·1-1262·8) in South Sudan to 2·4 (1·6-3·6) in Iceland.INTERPRETATION: Global rates of change suggest that only 16 countries will achieve the MDG 5 target by 2015. Accelerated reductions since the Millennium Declaration in 2000 coincide with increased development assistance for maternal, newborn, and child health. Setting of targets and associated interventions for after 2015 will need careful consideration of regions that are making slow progress, such as west and central Africa.FUNDING: Bill & Melinda Gates Foundation.

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    The Lancet
    Article
    Data sources: UnpayWall
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    Europe PubMed Central
    Other literature type . 2014
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    The Lancet
    Article . 2014
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    NARCIS; Research@WUR
    Other literature type . Article . 2014
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    The Lancet
    Article . 2014 . Peer-reviewed
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    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    The Lancet
    Article . 2014
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      The Lancet
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      NARCIS; Research@WUR
      Other literature type . Article . 2014
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      The Lancet
      Article . 2014 . Peer-reviewed
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      The Lancet
      Article . 2014
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    Authors: Jose S. Cánovas; Tönu Puu; Manuel Ruiz Marín;

    This paper is devoted to the study of the dynamics of a non-autonomous affine system. We apply the results to a two-region business cycle model of the Samuelson [Interactions between the multiplier ...

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    Chaos Solitons & Fractals
    Article . 2007 . Peer-reviewed
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      Chaos Solitons & Fractals
      Article . 2007 . Peer-reviewed
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    Authors: Jinesh, Mathew; Yuliya, Semenova; Gerald, Farrell;

    We demonstrate a novel miniature optical breathing sensor based on an Agarose infiltrated photonic crystal fiber interferometer. The sensor detects the variation in relative humidity that occurs between inhaled and exhaled breath. The sensor interrogation system can determine the breathing pattern in real time and can also predict the breathing rate and the breathing status during respiration. The sensor is suitable for monitoring patients during a magnetic resonance imaging scan where use of sedatives and anesthetics necessitates breathing monitoring; electronic sensors are not suitable in such an environment and a visual observation of the patient's respiratory efforts is often difficult.

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    Biomedical Optics Express
    Article . 2012 . Peer-reviewed
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      Biomedical Optics Express
      Article . 2012 . Peer-reviewed
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    Authors: Maria A K, Westin; Mary C, Hunt; Stefan E H, Alexson;

    Phytanic acid and pristanic acid are derived from phytol, which enter the body via the diet. Phytanic acid contains a methyl group in position three and, therefore, cannot undergo beta-oxidation directly but instead must first undergo alpha-oxidation to pristanic acid, which then enters beta-oxidation. Both these pathways occur in peroxisomes, and in this study we have identified a novel peroxisomal acyl-CoA thioesterase named ACOT6, which we show is specifically involved in phytanic acid and pristanic acid metabolism. Sequence analysis of ACOT6 revealed a putative peroxisomal targeting signal at the C-terminal end, and cellular localization experiments verified it as a peroxisomal enzyme. Subcellular fractionation experiments showed that peroxisomes contain by far the highest phytanoyl-CoA/pristanoyl-CoA thioesterase activity in the cell, which could be almost completely immunoprecipitated using an ACOT6 antibody. Acot6 mRNA was mainly expressed in white adipose tissue and was co-expressed in tissues with Acox3 (the pristanoyl-CoA oxidase). Furthermore, Acot6 was identified as a target gene of the peroxisome proliferator-activated receptor alpha (PPARalpha) and is up-regulated in mouse liver in a PPARalpha-dependent manner.

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    Journal of Biological Chemistry
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    Journal of Biological Chemistry
    Article . 2007 . Peer-reviewed
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    Arrow@TU Dublin
    Article . 2007
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      Journal of Biological Chemistry
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      Journal of Biological Chemistry
      Article . 2007 . Peer-reviewed
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      Arrow@TU Dublin
      Article . 2007
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    Authors: Aigars Lavrinovičs; Fredrika Murby; Elīna Zīverte; Linda Mežule; +1 Authors

    99% within 7 days. B. braunii maintained good biomass growth rate and nutrient removal regardless of the P-starvation. All species showed 2–5 times higher alkaline phosphatase activity increase for P-starved biomass than at the reference conditions, responding to the decline of PO4 concentration in wastewater and biomass poly-P content. The overall efficiency of biomass P-starvation on enhanced phosphorus uptake was found to be dependent on the species, N/P molar ratio in the wastewater, as well as the biomass P content. Four microalgal species, Chlorella vulgaris, Botryococcus braunii, Ankistrodesmus falcatus, and Tetradesmus obliquus were studied for enhanced phosphorus removal from municipal wastewater after their exposure to phosphorus starvation. Microalgae were exposed to phosphorus starvation conditions for three and five days and then used in a batch experiment to purify an effluent from a small WWTP. After 3-day P-starvation, C. vulgaris biomass growth rate increased by 50% and its PO4 removal rate reached >

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    Microorganisms
    Other literature type . Article . 2021 . Peer-reviewed
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    Microorganisms
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    Microorganisms
    Article . 2021
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    Article . 2021
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      Microorganisms
      Other literature type . Article . 2021 . Peer-reviewed
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      Microorganisms
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      Microorganisms
      Article . 2021
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Brigita Dalecka; Martins Strods; Talis Juhna; Gunaratna Kuttuva Rajarao;

    Discharge of organic load from treated wastewater may cause environmental eutrophication. Recently, fungi have gained much attention due to their removal of pharmaceutical substances by enzymatic degradation and adsorption. However, the fungal effect in removing nutrients is less investigated. Therefore, two fungal species, the white-rot fungus T. versicolor as a laboratory strain and the mold A. luchuensis as an environmental isolate from the municipal wastewater treatment plant, were studied to determine the fungal potential for phosphorus, nitrogen, and the total organic carbon removal from municipal wastewater, carrying out a batch scale experiment to a fluidized bed pelleted bioreactor. During the batch scale experiment, the total removal (99.9 %) of phosphorus by T. versicolor was attained after a 6 hours-long incubation period while the maximal removal efficiency (99.9 %) for phosphorus from A. luchuensis was gained after an incubation period of 24 hours. Furthermore, both fungi showed that the pH adjustment to 5.5 kept the concentration of nitrogen constant and stabilized the total organic carbon reduction process for the entire incubation period. The results from the fluidized bed bioreactor demonstrated opposite tendencies on a nutrient removal comparing to a batch experiment where no significant effect on phosphorus, nitrogen, and total organics carbon reduction was observed. The obtained results from this study of batch and fluidized bed bioreactor experiments are a promising starting point for a successful fungal treatment optimization and application to wastewater treatment. QC 20210107

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    Microbiological Research
    Article . 2020 . Peer-reviewed
    License: Elsevier Non-Commercial
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      Microbiological Research
      Article . 2020 . Peer-reviewed
      License: Elsevier Non-Commercial
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    Authors: Lin She; Niannian Xu; Pengfei Wang; Jiquan Zhang; +8 Authors

    This letter reports the fabrication of fiber Bragg gratings (FBGs) within in-house fabricated fluoroaluminate (AlF3) glass fibers using femtosecond (fs) laser inscription at 800 nm. The grating strength of the FBGs was investigated for different pulse energies and different orders, and a 3rd-order FBG with Bragg wavelength at 1557 nm was found to have the highest reflectivity of 99.5%. In addition, the reflectivity of the mid-IR grating peaks for different orders was also studied, and a 2nd-order FBG with a reflectivity of 98.8% was obtained at 2864 nm. Finally, the temperature characteristics of a mid-IR FBG were studied between 30 °C and 150 °C, showing a linear wavelength dependence and an excellent stability for the refractive index modulation. Such highly reflectivity FBGs in AlF3 fiber have significant potential for applications in the development of compact all-fiber mid-IR fiber lasers.

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    Arrow@TU Dublin
    Article . 2022
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    https://doi.org/10.1109/jphot....
    Article . 2022 . Peer-reviewed
    License: CC BY
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      Arrow@TU Dublin
      Article . 2022
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      https://doi.org/10.1109/jphot....
      Article . 2022 . Peer-reviewed
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Rio, Maud; Reyes, Tatiana; Roucoules, Lionel;

    Lien vers la version éditeur: http://annals.fih.upt.ro/pdf-full/2011/ANNALS-2011-1-17.pdf; International audience; Integrating environmental aspects in the design process is getting more and more covered by the actual scientific research. Based on various fields such as "eco-design", "Design for sustainability", "eco-innovation", several specific software and methods have been developed to tackle this issue. Our work focuses on product designer software and eco-designer software that already exist. This research analyses product design and eco-design--considering their respective complexity--in order to determine the main difficulties to systematically integrate environmental aspects in the design process. Our observations have led us to work on three elements: information, software, and collaboration between designers and LCA expert. The principal objective is to facilitate the interface between product design and eco-design by linking the requirements and performances of both domains. It seems therefore necessary to help the collaboration between various experts and thus to develop a digital interface enabling designers to exchange data and to use their appropriate related software. The aim of this paper is to argue the need of a digital tool interfacing the actual tools of the design process and of eco-design (among the related software such as CAD, CAx, PLM, and LCA). This "digital interface" is presented at the end of the paper and will be created next year.

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    Authors: Blancher, Philippe; Lefrançois, Estelle; Rimet, Frédéric; Vasselon, Valentin; +53 Authors

    Recent advances in molecular biomonitoring open new horizons for aquatic ecosystem assessment. Rapid and cost-effective methods based on organismal DNA or environmental DNA (eDNA) now offer the opportunity to produce inventories of indicator taxa that can subsequently be used to assess biodiversity and ecological quality. However, the integration of these new DNA-based methods into current monitoring practices is not straightforward, and will require coordinated actions in the coming years at national and international levels. To plan and stimulate such an integration, the European network DNAqua-Net (COST Action CA15219) brought together international experts from academia, as well as key environmental biomonitoring stakeholders from different European countries. Together, this transdisciplinary consortium developed a roadmap for implementing DNA-based methods with a focus on inland waters assessed by the EU Water Framework Directive (2000/60/EC). This was done through a series of online workshops held in April 2020, which included fifty participants, followed by extensive synthesis work. The roadmap is organised around six objectives: 1) to highlight the effectiveness and benefits of DNA-based methods, 2) develop an adaptive approach for the implementation of new methods, 3) provide guidelines and standards for best practice, 4) engage stakeholders and ensure effective knowledge transfer, 5) support the environmental biomonitoring sector to achieve the required changes, 6) steer the process and harmonise efforts at the European level. This paper provides an overview of the forum discussions and the common European views that have emerged from them, while reflecting the diversity of situations in different countries. It highlights important actions required for a successful implementation of DNA-based biomonitoring of aquatic ecosystems by 2030.

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    Ktisis
    Article . 2022
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    Metabarcoding and Metagenomics; ZENODO
    Article . 2022 . Peer-reviewed
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      Metabarcoding and Metagenomics; ZENODO
      Article . 2022 . Peer-reviewed
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    Authors: Ekaterini Lambrinou; Tiny Jaarsma; Ewa Piotrowicz; Petar M. Seferović; +2 Authors

    Although exercise training has been found to be beneficial for the physical capacity and exercise tolerance in heart failure (HF) patients,1 and even though exercise training is recommended as a class I non-pharmacological treatment,2 only a few patients adhere to exercise training or some fail to exercise at all.1 In a recent survey performed by the Heart Failure Association of the European Society of Cardiology in collaboration with the HF National Societies the diversity in management of HF patients in Europe was described.3 In the survey it was also noted that 25 of the 33 responding countries reported that they have HF clinics in their country and it is known that only a limited number of them include an exercise component in HF rehabilitation programmes.4.

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    Article . 2014
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    European Journal of Cardiovascular Nursing
    Article . 2014 . Peer-reviewed
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      European Journal of Cardiovascular Nursing
      Article . 2014 . Peer-reviewed
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    Authors: Nicholas J Kassebaum; Amelia Bertozzi-Villa; Megan Coggeshall; Katya Anne Shackelford; +253 Authors

    BACKGROUND: The fifth Millennium Development Goal (MDG 5) established the goal of a 75% reduction in the maternal mortality ratio (MMR; number of maternal deaths per 100,000 livebirths) between 1990 and 2015. We aimed to measure levels and track trends in maternal mortality, the key causes contributing to maternal death, and timing of maternal death with respect to delivery.METHODS: We used robust statistical methods including the Cause of Death Ensemble model (CODEm) to analyse a database of data for 7065 site-years and estimate the number of maternal deaths from all causes in 188 countries between 1990 and 2013. We estimated the number of pregnancy-related deaths caused by HIV on the basis of a systematic review of the relative risk of dying during pregnancy for HIV-positive women compared with HIV-negative women. We also estimated the fraction of these deaths aggravated by pregnancy on the basis of a systematic review. To estimate the numbers of maternal deaths due to nine different causes, we identified 61 sources from a systematic review and 943 site-years of vital registration data. We also did a systematic review of reports about the timing of maternal death, identifying 142 sources to use in our analysis. We developed estimates for each country for 1990-2013 using Bayesian meta-regression. We estimated 95% uncertainty intervals (UIs) for all values.FINDINGS: 292,982 (95% UI 261,017-327,792) maternal deaths occurred in 2013, compared with 376,034 (343,483-407,574) in 1990. The global annual rate of change in the MMR was -0·3% (-1·1 to 0·6) from 1990 to 2003, and -2·7% (-3·9 to -1·5) from 2003 to 2013, with evidence of continued acceleration. MMRs reduced consistently in south, east, and southeast Asia between 1990 and 2013, but maternal deaths increased in much of sub-Saharan Africa during the 1990s. 2070 (1290-2866) maternal deaths were related to HIV in 2013, 0·4% (0·2-0·6) of the global total. MMR was highest in the oldest age groups in both 1990 and 2013. In 2013, most deaths occurred intrapartum or postpartum. Causes varied by region and between 1990 and 2013. We recorded substantial variation in the MMR by country in 2013, from 956·8 (685·1-1262·8) in South Sudan to 2·4 (1·6-3·6) in Iceland.INTERPRETATION: Global rates of change suggest that only 16 countries will achieve the MDG 5 target by 2015. Accelerated reductions since the Millennium Declaration in 2000 coincide with increased development assistance for maternal, newborn, and child health. Setting of targets and associated interventions for after 2015 will need careful consideration of regions that are making slow progress, such as west and central Africa.FUNDING: Bill & Melinda Gates Foundation.

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    The Lancet
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    The Lancet
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    NARCIS; Research@WUR
    Other literature type . Article . 2014
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    The Lancet
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    The Lancet
    Article . 2014
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      The Lancet
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      The Lancet
      Article . 2014
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    Authors: Jose S. Cánovas; Tönu Puu; Manuel Ruiz Marín;

    This paper is devoted to the study of the dynamics of a non-autonomous affine system. We apply the results to a two-region business cycle model of the Samuelson [Interactions between the multiplier ...

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    Chaos Solitons & Fractals
    Article . 2007 . Peer-reviewed
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      Chaos Solitons & Fractals
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    Authors: Jinesh, Mathew; Yuliya, Semenova; Gerald, Farrell;

    We demonstrate a novel miniature optical breathing sensor based on an Agarose infiltrated photonic crystal fiber interferometer. The sensor detects the variation in relative humidity that occurs between inhaled and exhaled breath. The sensor interrogation system can determine the breathing pattern in real time and can also predict the breathing rate and the breathing status during respiration. The sensor is suitable for monitoring patients during a magnetic resonance imaging scan where use of sedatives and anesthetics necessitates breathing monitoring; electronic sensors are not suitable in such an environment and a visual observation of the patient's respiratory efforts is often difficult.

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    Biomedical Optics Express
    Article . 2012 . Peer-reviewed
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      Biomedical Optics Express
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    Authors: Maria A K, Westin; Mary C, Hunt; Stefan E H, Alexson;

    Phytanic acid and pristanic acid are derived from phytol, which enter the body via the diet. Phytanic acid contains a methyl group in position three and, therefore, cannot undergo beta-oxidation directly but instead must first undergo alpha-oxidation to pristanic acid, which then enters beta-oxidation. Both these pathways occur in peroxisomes, and in this study we have identified a novel peroxisomal acyl-CoA thioesterase named ACOT6, which we show is specifically involved in phytanic acid and pristanic acid metabolism. Sequence analysis of ACOT6 revealed a putative peroxisomal targeting signal at the C-terminal end, and cellular localization experiments verified it as a peroxisomal enzyme. Subcellular fractionation experiments showed that peroxisomes contain by far the highest phytanoyl-CoA/pristanoyl-CoA thioesterase activity in the cell, which could be almost completely immunoprecipitated using an ACOT6 antibody. Acot6 mRNA was mainly expressed in white adipose tissue and was co-expressed in tissues with Acox3 (the pristanoyl-CoA oxidase). Furthermore, Acot6 was identified as a target gene of the peroxisome proliferator-activated receptor alpha (PPARalpha) and is up-regulated in mouse liver in a PPARalpha-dependent manner.

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    Journal of Biological Chemistry
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    Journal of Biological Chemistry
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    Arrow@TU Dublin
    Article . 2007
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      Journal of Biological Chemistry
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      Arrow@TU Dublin
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    Authors: Aigars Lavrinovičs; Fredrika Murby; Elīna Zīverte; Linda Mežule; +1 Authors

    99% within 7 days. B. braunii maintained good biomass growth rate and nutrient removal regardless of the P-starvation. All species showed 2–5 times higher alkaline phosphatase activity increase for P-starved biomass than at the reference conditions, responding to the decline of PO4 concentration in wastewater and biomass poly-P content. The overall efficiency of biomass P-starvation on enhanced phosphorus uptake was found to be dependent on the species, N/P molar ratio in the wastewater, as well as the biomass P content. Four microalgal species, Chlorella vulgaris, Botryococcus braunii, Ankistrodesmus falcatus, and Tetradesmus obliquus were studied for enhanced phosphorus removal from municipal wastewater after their exposure to phosphorus starvation. Microalgae were exposed to phosphorus starvation conditions for three and five days and then used in a batch experiment to purify an effluent from a small WWTP. After 3-day P-starvation, C. vulgaris biomass growth rate increased by 50% and its PO4 removal rate reached >

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    Microorganisms
    Other literature type . Article . 2021 . Peer-reviewed
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    Microorganisms
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    Microorganisms
    Article . 2021
    Data sources: DOAJ-Articles
    DOAJ
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Europe PubMed Centra...arrow_drop_down
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      Microorganisms
      Other literature type . Article . 2021 . Peer-reviewed
      License: CC BY
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Microorganisms
      Article
      License: CC BY
      Data sources: UnpayWall
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      Microorganisms
      Article . 2021
      Data sources: DOAJ-Articles
      DOAJ
      Article . 2021
      Data sources: DOAJ
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