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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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EcoliWiki is a community-based resource for the annotation of all non-pathogenic E. coli, its phages, plasmids, and mobile genetic elements. Users can contribute data to this wiki-style repository.
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The NINDS Human Cell and Data Repository (NHCDR) provides access to fibroblast and/or induced pluripotent stem cell (iPSC) lines for a number neurological disorders within the NINDS mission as well as healthy controls. NHCDR also supports access to unique iPSC collections from NeuroLINCS, PDBP, LEFFTDS and Target ALS with associated metadata. A GMP-grade iPSC line and corresponding research grade iPSC line are also available through the NHCDR.
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mirDNMR is a database for the collection of gene-centered background DNMRs obtained from different methods and population variation data. The database has the following functions: (i) browse and search the background DNMRs of each gene predicted by four different methods, including GC content (DNMR-GC), sequence context (DNMR-SC), multiple factors (DNMR-MF) and local DNA methylation level (DNMR-DM); (ii) search variant frequencies in publicly available databases, including ExAC, ESP6500, UK10K, 1000G and dbSNP and (iii) investigate the DNM burden to prioritize candidate genes based on the four background DNMRs using three statistical methods (TADA, Binomial and Poisson test). In conclusion, mirDNMR can be widely used to identify the genetic basis of sporadic genetic diseases.
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EcoliWiki is a community-based resource for the annotation of all non-pathogenic E. coli, its phages, plasmids, and mobile genetic elements. Users can contribute data to this wiki-style repository.
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The NINDS Human Cell and Data Repository (NHCDR) provides access to fibroblast and/or induced pluripotent stem cell (iPSC) lines for a number neurological disorders within the NINDS mission as well as healthy controls. NHCDR also supports access to unique iPSC collections from NeuroLINCS, PDBP, LEFFTDS and Target ALS with associated metadata. A GMP-grade iPSC line and corresponding research grade iPSC line are also available through the NHCDR.
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